The role of IL-22 in intestinal health and disease

por Keir, Mary E., Yi, Tangsheng, Lu, Timothy T., Ghilardi, Nico
Publicado 2020

IFN-α-Induced Upregulation of CCR5 Leads to Expanded HIV Tropism In Vivo

por Stoddart, Cheryl A., Keir, Mary E., McCune, Joseph M.
Publicado 2010

Identification of an IL-22-Dependent Gene Signature as a Pharmacodynamic Biomarker

por Rae, Julie, Hackney, Jason, Huang, Kevin, Keir, Mary, Herman, Ann
Publicado 2021

T Lymphocytes Expressing AlphaE Beta7 Integrin in Ulcerative Colitis: Associations With Cellular Lineage and Phenotype

por Lamb, Christopher A, Kirby, John A, Keir, Mary E, Mansfield, John C
Publicado 2017

The Importance of Molecular Immune Investigation in Therapeutic Clinical Development for Biomarker Assessment

por Lamb, Christopher A, Mansfield, John C, Kirby, John A, Keir, Mary E
Publicado 2019

The role of integrins in the pathogenesis of inflammatory bowel disease: Approved and investigational anti‐integrin therapies

por Dotan, Iris, Allez, Matthieu, Danese, Silvio, Keir, Mary, Tole, Swati, McBride, Jacqueline
Publicado 2019

CD28 Costimulation Regulates Genome-Wide Effects on Alternative Splicing

por Butte, Manish J., Lee, Sun Jung, Jesneck, Jonathan, Keir, Mary E., Haining, W. Nicholas, Sharpe, Arlene H.
Publicado 2012

Discrepancies between patient-reported outcomes, and endoscopic and histological appearance in UC

por Colombel, Jean-Frédéric, Keir, Mary E, Scherl, Alexis, Zhao, Rui, de Hertogh, Gert, Faubion, William A, Lu, Timothy T
Publicado 2017

Tissue expression of PD-L1 mediates peripheral T cell tolerance

por Keir, Mary E., Liang, Spencer C., Guleria, Indira, Latchman, Yvette E., Qipo, Andi, Albacker, Lee A., Koulmanda, Maria, Freeman, Gordon J., Sayegh, Mohamed H., Sharpe, Arlene H.
Publicado 2006

Dose escalation randomised study of efmarodocokin alfa in healthy volunteers and patients with ulcerative colitis

por Wagner, Frank, Mansfield, John C, Lekkerkerker, Annemarie N, Wang, Yehong, Keir, Mary, Dash, Ajit, Butcher, Brandon, Harder, Brandon, Orozco, Luz D, Mar, Jordan S, Chen, Hao, Rothenberg, Michael E
Publicado 2023

IL-22 alters gut microbiota composition and function to increase aryl hydrocarbon receptor activity in mice and humans

por Mar, Jordan S., Ota, Naruhisa, Pokorzynski, Nick D., Peng, Yutian, Jaochico, Allan, Sangaraju, Dewakar, Skippington, Elizabeth, Lekkerkerker, Annemarie N., Rothenberg, Michael E., Tan, Man-Wah, Yi, Tangsheng, Keir, Mary E.
Publicado 2023

AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation

por Ichikawa, Ryan, Lamb, Christopher A, Eastham-Anderson, Jeff, Scherl, Alexis, Raffals, Laura, Faubion, William A, Bennett, Miriam R, Long, Anna K, Mansfield, John C, Kirby, John A, Keir, Mary E
Publicado 2018

A randomised phase I study of etrolizumab (rhuMAb β7) in moderate to severe ulcerative colitis

por Rutgeerts, Paul J, Fedorak, Richard N, Hommes, Daan W, Sturm, Andreas, Baumgart, Daniel C, Bressler, Brian, Schreiber, Stefan, Mansfield, John C, Williams, Marna, Tang, Meina, Visich, Jennifer, Wei, Xiaohui, Keir, Mary, Luca, Diana, Danilenko, Dimitri, Egen, Jackson, O'Byrne, Sharon
Publicado 2013

αEβ7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis

por Lamb, Christopher A., Mansfield, John C., Tew, Gaik W., Gibbons, Deena, Long, Anna K., Irving, Peter, Diehl, Lauri, Eastham-Anderson, Jeff, Price, Maria B., O’Boyle, Graeme, Jones, David E. J., O’Byrne, Sharon, Hayday, Adrian, Keir, Mary E., Egen, Jackson G., Kirby, John A.
Publicado 2017

Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease

por Keir, Mary E., Fuh, Franklin, Ichikawa, Ryan, Acres, Meghan, Hackney, Jason A., Hulme, Gillian, Carey, Christopher D., Palmer, Jeremy, Jones, Claire J., Long, Anna K., Jiang, Jenny, Klabunde, Sha, Mansfield, John C., Looney, Cary M., Faubion, William A., Filby, Andrew, Kirby, John A., McBride, Jacqueline, Lamb, Christopher A.
Publicado 2021

Functional Consequences of the Macrophage Stimulating Protein 689C Inflammatory Bowel Disease Risk Allele

por Kauder, Steven E., Santell, Lydia, Mai, Elaine, Wright, Lilyan Y., Luis, Elizabeth, N'Diaye, Elsa N., Lutman, Jeff, Ratti, Navneet, Sa, Susan M., Maun, Henry R., Stefanich, Eric, Gonzalez, Lino C., Graham, Robert R., Diehl, Lauri, Faubion, William A., Keir, Mary E., Young, Judy, Chaudhuri, Amitabha, Lazarus, Robert A., Egen, Jackson G.
Publicado 2013

Dual targeting of lymphocyte homing and retention through α4β7 and αEβ7 inhibition in inflammatory bowel disease

por Dai, Bingbing, Hackney, Jason A., Ichikawa, Ryan, Nguyen, Allen, Elstrott, Justin, Orozco, Luz D., Sun, Kai-Hui, Modrusan, Zora, Gogineni, Alvin, Scherl, Alexis, Gubatan, John, Habtezion, Aida, Deswal, Monika, Somsouk, Ma, Faubion, William A., Chai, Akiko, Sharafali, Zaineb, Hassanali, Azra, Oh, Young S., Tole, Swati, McBride, Jacqueline, Keir, Mary E., Yi, Tangsheng
Publicado 2021

An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases

por Xie, Markus M., Dai, Bingbing, Hackney, Jason A., Sun, Tianhe, Zhang, Juan, Jackman, Janet K., Jeet, Surinder, Irizarry-Caro, Ricardo A., Fu, Yongyao, Liang, Yuxin, Bender, Hannah, Shamir, Eliah R., Keir, Mary E., Bevers, Jack, Nakamura, Gerald, Townsend, Michael J., Fox, David A., Scherl, Alexis, Lee, Wyne P., Martin, Flavius, Godowski, Paul J., Pappu, Rajita, Yi, Tangsheng
Publicado 2023

Magnetic Resonance Enterography and Histology in Patients With Fibrostenotic Crohn's Disease: A Multicenter Study

por Coimbra, Alexandre, Rimola, Jordi, Cuatrecasas, Miriam, De Hertogh, Gert, Van Assche, Gert, Vanslembrouck, Ragna, Glerup, Henning, Nielsen, Agnete Hedemann, Hagemann-Madsen, Rikke, Bouhnik, Yoram, Zappa, Magaly, Cazals-Hatem, Dominique, D'Haens, Geert, Stoker, Jaap, Meijer, Sybren, Rogler, Gerhard, Boss, Andreas, Weber, Achim, Zhao, Rui, Keir, Mary E., Scherl, Alexis, de Crespigny, Alex, Lu, Timothy T., Panés, Julián
Publicado 2022

Function of CSF1 and IL34 in Macrophage Homeostasis, Inflammation, and Cancer

por Lin, WeiYu, Xu, Daqi, Austin, Cary D., Caplazi, Patrick, Senger, Kate, Sun, Yonglian, Jeet, Surinder, Young, Judy, Delarosa, Donnie, Suto, Eric, Huang, Zhiyu, Zhang, Juan, Yan, Donghong, Corzo, Cesar, Barck, Kai, Rajan, Sharmila, Looney, Carrie, Gandham, Vineela, Lesch, Justin, Liang, Wei-Ching, Mai, Elaine, Ngu, Hai, Ratti, Navneet, Chen, Yongmei, Misner, Dinah, Lin, Tori, Danilenko, Dimitry, Katavolos, Paula, Doudemont, Estelle, Uppal, Hirdesh, Eastham, Jeffrey, Mak, Judy, de Almeida, Patricia E., Bao, Katherine, Hadadianpour, Azadeh, Keir, Mary, Carano, Richard A. D., Diehl, Lauri, Xu, Min, Wu, Yan, Weimer, Robby M., DeVoss, Jason, Lee, Wyne P., Balazs, Mercedesz, Walsh, Kevin, Alatsis, Kathila R., Martin, Flavius, Zarrin, Ali A.
Publicado 2019