PEAK1, a Novel Kinase Target in the Fight Against Cancer

por Kelber, Jonathan A., Klemke, Richard L.
Publicado 2010

Ascending the PEAK1 toward targeting TGFβ during cancer progression: Recent advances and future perspectives

por Runa, Farhana, Adamian, Yvess, Kelber, Jonathan A.
Publicado 2016

Designer TGFβ Superfamily Ligands with Diversified Functionality

por Allendorph, George P., Read, Jessica D., Kawakami, Yasuhiko, Kelber, Jonathan A., Isaacs, Michael J., Choe, Senyon
Publicado 2011

PEAK1 Acts as a Molecular Switch to Regulate Context-Dependent TGFβ Responses in Breast Cancer

por Agajanian, Megan, Campeau, Anaamika, Hoover, Malachia, Hou, Alexander, Brambilla, Daniel, Kim, Sa La, Klemke, Richard L., Kelber, Jonathan A.
Publicado 2015

Secretomes from metastatic breast cancer cells, enriched for a prognostically unfavorable LCN2 axis, induce anti-inflammatory MSC actions and a tumor-supportive premetastatic lung

por Meade, Kayla J., Sanchez, Francesca, Aguayo, Analine, Nadales, Nathalie, Hamalian, Sarkis G., Uhlendorf, Toni L., Banner, Lisa R., Kelber, Jonathan A.
Publicado 2019

Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor Resistance

por Geller, Cameron, Maddela, Joanna, Tuplano, Ranel, Runa, Farhana, Adamian, Yvess, Güth, Robert, Ortiz Soto, Gabriela, Tomaneng, Luke, Cantor, Joseph, Kelber, Jonathan A.
Publicado 2023

ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer

por Gharibi, Armen, La Kim, Sa, Molnar, Justin, Brambilla, Daniel, Adamian, Yvess, Hoover, Malachia, Hong, Julie, Lin, Joy, Wolfenden, Laurelin, Kelber, Jonathan A.
Publicado 2017

Fibrillin-1 mutant mouse captures defining features of human primary open glaucoma including anomalous aqueous humor TGF beta-2

por Ko, MinHee K., Woo, Jeong-Im, Gonzalez, Jose M., Kim, Gayeoun, Sakai, Lynn, Peti-Peterdi, Janos, Kelber, Jonathan A., Hong, Young-Kwon, Tan, James C.
Publicado 2022

CRIPTO/GRP78 Signaling Maintains Fetal and Adult Mammary Stem Cells Ex Vivo

por Spike, Benjamin T., Kelber, Jonathan A., Booker, Evan, Kalathur, Madhuri, Rodewald, Rose, Lipianskaya, Julia, La, Justin, He, Marielle, Wright, Tracy, Klemke, Richard, Wahl, Geoffrey M., Gray, Peter C.
Publicado 2014

A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xe...

por Hoover, Malachia, Adamian, Yvess, Brown, Mark, Maawy, Ali, Chang, Alexander, Lee, Jacqueline, Gharibi, Armen, Katz, Matthew H, Fleming, Jason, Hoffman, Robert M, Bouvet, Michael, Doebler, Robert, Kelber, Jonathan A
Publicado 2016

A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic a...

por Hamalian, Sarkis, Güth, Robert, Runa, Farhana, Sanchez, Francesca, Vickers, Eric, Agajanian, Megan, Molnar, Justin, Nguyen, Tuan, Gamez, Joshua, Humphries, Jonathan D., Nayak, Anupma, Humphries, Martin J., Tchou, Julia, Zervantonakis, Ioannis K., Kelber, Jonathan A.
Publicado 2021

Cell surface GRP78 promotes stemness in normal and neoplastic cells

por Conner, Clay, Lager, Tyson W., Guldner, Ian H., Wu, Min-Zu, Hishida, Yuriko, Hishida, Tomoaki, Ruiz, Sergio, Yamasaki, Amanda E., Gilson, Robert C., Belmonte, Juan Carlos Izpisua, Gray, Peter C., Kelber, Jonathan A., Zhang, Siyuan, Panopoulos, Athanasia D.
Publicado 2020