Binding Mode and Potency of N-Indolyloxopyridinyl-4-aminopropanyl-Based Inhibitors Targeting Trypanosoma cruzi CYP51

por Vieira, Debora F., Choi, Jun Yong, Calvet, Claudia M., Siqueira-Neto, Jair Lage, Johnston, Jonathan B., Kellar, Danielle, Gut, Jiri, Cameron, Michael D., McKerrow, James H., Roush, William R., Podust, Larissa M.
Publicado 2014

Machine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug Discovery

por Ekins, Sean, Lage de Siqueira-Neto, Jair, McCall, Laura-Isobel, Sarker, Malabika, Yadav, Maneesh, Ponder, Elizabeth L., Kallel, E. Adam, Kellar, Danielle, Chen, Steven, Arkin, Michelle, Bunin, Barry A., McKerrow, James H., Talcott, Carolyn
Publicado 2015

4-Aminopyridyl-Based CYP51 Inhibitors as Anti-Trypanosoma cruzi Drug Leads with Improved Pharmacokinetic Profile and in Vivo Potency

por Calvet, Claudia M., Vieira, Debora F., Choi, Jun Yong, Kellar, Danielle, Cameron, Michael D., Siqueira-Neto, Jair Lage, Gut, Jiri, Johnston, Jonathan B., Lin, Li, Khan, Susan, McKerrow, James H., Roush, William R., Podust, Larissa M.
Publicado 2014

Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase

por McCall, Laura-Isobel, El Aroussi, Amale, Choi, Jun Yong, Vieira, Debora F., De Muylder, Geraldine, Johnston, Jonathan B., Chen, Steven, Kellar, Danielle, Siqueira-Neto, Jair L., Roush, William R., Podust, Larissa M., McKerrow, James H.
Publicado 2015