RUNX1-EVI1 disrupts lineage determination and the cell cycle by interfering with RUNX1 and EVI1 driven gene regulatory networks

por Kellaway, Sophie G., Keane, Peter, Kennett, Ella, Bonifer, Constanze
Publicado 2020

Different mutant RUNX1 oncoproteins program alternate haematopoietic differentiation trajectories

por Kellaway, Sophie G, Keane, Peter, Edginton-White, Benjamin, Regha, Kakkad, Kennett, Ella, Bonifer, Constanze
Publicado 2021

Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism

por Kellaway, Sophie G., Mosinska, Karolina, Mohamed, Zainaba, Ryan, Alexander, Richardson, Stephen, Newbould, Melanie, Banerjee, Indraneel, Dunne, Mark J., Cosgrove, Karen E.
Publicado 2019

Correction: Increased proliferation and altered cell cycle regulation in pancreatic stem cells derived from patients with congenital hyperinsulinism

por Kellaway, Sophie G., Mosinska, Karolina, Mohamed, Zainaba, Ryan, Alexander, Richardson, Stephen, Newbould, Melanie, Banerjee, Indraneel, Dunne, Mark J., Cosgrove, Karen E.
Publicado 2019

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia

por Adamo, Assunta, Chin, Paulynn, Keane, Peter, Assi, Salam A., Potluri, Sandeep, Kellaway, Sophie G., Coleman, Daniel, Ames, Luke, Ptasinska, Anetta, Delwel, H. Ruud, Cockerill, Peter N., Bonifer, Constanze
Publicado 2022

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

por Coleman, Daniel J.L., Keane, Peter, Luque-Martin, Rosario, Chin, Paulynn S, Blair, Helen, Ames, Luke, Kellaway, Sophie G., Griffin, James, Holmes, Elizabeth, Potluri, Sandeep, Assi, Salam A., Bushweller, John, Heidenreich, Olaf, Cockerill, Peter N., Bonifer, Constanze
Publicado 2023

Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia

por Tirtakusuma, Ricky, Szoltysek, Katarzyna, Milne, Paul, Grinev, Vasily V., Ptasinska, Anetta, Chin, Paulynn S., Meyer, Claus, Nakjang, Sirintra, Hehir-Kwa, Jayne Y., Williamson, Daniel, Cauchy, Pierre, Keane, Peter, Assi, Salam A., Ashtiani, Minoo, Kellaway, Sophie G., Imperato, Maria R., Vogiatzi, Fotini, Schweighart, Elizabeth K., Lin, Shan, Wunderlich, Mark, Stutterheim, Janine, Komkov, Alexander, Zerkalenkova, Elena, Evans, Paul, McNeill, Hesta, Elder, Alex, Martinez-Soria, Natalia, Fordham, Sarah E., Shi, Yuzhe, Russell, Lisa J., Pal, Deepali, Smith, Alex, Kingsbury, Zoya, Becq, Jennifer, Eckert, Cornelia, Haas, Oskar A., Carey, Peter, Bailey, Simon, Skinner, Roderick, Miakova, Natalia, Collin, Matthew, Bigley, Venetia, Haniffa, Muzlifah, Marschalek, Rolf, Harrison, Christine J., Cargo, Catherine A., Schewe, Denis, Olshanskaya, Yulia, Thirman, Michael J., Cockerill, Peter N., Mulloy, James C., Blair, Helen J., Vormoor, Josef, Allan, James M., Bonifer, Constanze, Heidenreich, Olaf, Bomken, Simon
Publicado 2022