CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

por Wegmann, Rebekka, Neri, Marilisa, Schuierer, Sven, Bilican, Bilada, Hartkopf, Huyen, Nigsch, Florian, Mapa, Felipa, Waldt, Annick, Cuttat, Rachel, Salick, Max R., Raymond, Joe, Kaykas, Ajamete, Roma, Guglielmo, Keller, Caroline Gubser
Publicado 2019

DRUG-seq for miniaturized high-throughput transcriptome profiling in drug discovery

por Ye, Chaoyang, Ho, Daniel J., Neri, Marilisa, Yang, Chian, Kulkarni, Tripti, Randhawa, Ranjit, Henault, Martin, Mostacci, Nadezda, Farmer, Pierre, Renner, Steffen, Ihry, Robert, Mansur, Leandra, Keller, Caroline Gubser, McAllister, Gregory, Hild, Marc, Jenkins, Jeremy, Kaykas, Ajamete
Publicado 2018

Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization

por Surdziel, Ewa, Clay, Ieuan, Nigsch, Florian, Thiemeyer, Anke, Allard, Cyril, Hoffman, Gregory, Reece-Hoyes, John S., Phadke, Tanushree, Gambert, Romain, Keller, Caroline Gubser, Ludwig, Marie-Gabrielle, Baumgarten, Birgit, Frederiksen, Mathias, Schübeler, Dirk, Seuwen, Klaus, Bouwmeester, Tewis, Fodor, Barna D.
Publicado 2017

An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion

por Keller, Caroline Gubser, Shin, Youngah, Monteys, Alex Mas, Renaud, Nicole, Beibel, Martin, Teider, Natalia, Peters, Thomas, Faller, Thomas, St-Cyr, Sophie, Knehr, Judith, Roma, Guglielmo, Reyes, Alejandro, Hild, Marc, Lukashev, Dmitriy, Theil, Diethilde, Dales, Natalie, Cha, Jang-Ho, Borowsky, Beth, Dolmetsch, Ricardo, Davidson, Beverly L., Sivasankaran, Rajeev
Publicado 2022

STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia

por Morozzi, Giulio, Rothen, Julian, Toussaint, Gauthier, De Lange, Katrina, Westritschnig, Katrin, Doelemeyer, Arno, Ueberschlag, Vanessa Pitiot, Kahle, Peter, Lambert, Christian, Obrecht, Michael, Beckmann, Nicolau, Ritter, Veronique, Panesar, Moh, Stauffer, Daniela, Garnier, Isabelle, Mueller, Matthias, Guerini, Danilo, Keller, Caroline Gubser, Knehr, Judith, Roma, Guglielmo, Bidinosti, Michael, Brachat, Sophie, Morvan, Frederic, Fornaro, Mara
Publicado 2021