A Dual-Sensor-Based Screening System for In Vitro Selection of TDP1 Inhibitors

por Jakobsen, Ann-Katrine, Keller, Josephine Geertsen, Gonzalez, María, Martin-Encinas, Endika, Palacios, Francisco, Alonso, Concepcion, Knudsen, Birgitta Ruth, Stougaard, Magnus
Publicado 2021

Different Camptothecin Sensitivities in Subpopulations of Colon Cancer Cells Correlate with Expression of Different Phospho-Isoforms of Topoisomerase I with Different Activities

por Tesauro, Cinzia, Keller, Josephine Geertsen, Gromova, Irina, Gromov, Pavel, Frøhlich, Rikke, Erlandsen, Jens Uldum, Andersen, Anni H., Stougaard, Magnus, Knudsen, Birgitta R.
Publicado 2020

Topoisomerase 1 Activity Is Reduced in Response to Thermal Stress in Fruit Flies and in Human HeLa Cells

por Juul-Kristensen, Trine, Keller, Josephine Geertsen, Borg, Kathrine Nygaard, Hansen, Noriko Y., Foldager, Amalie, Ladegaard, Rasmus, Ho, Yi-Ping, Loeschcke, Volker, Knudsen, Birgitta R.
Publicado 2023

Rolling Circle Enhanced Detection of Specific Restriction Endonuclease Activities in Crude Cell Extracts

por Petersen, Kamilla Vandsø, Tesauro, Cinzia, Hede, Marianne Smedegaard, Pages, Camilla, Marcussen, Lærke Bay, Keller, Josephine Geertsen, Bugge, Magnus, Holm, Kasper, Bjergbæk, Lotte, Stougaard, Magnus, Wejse, Christian, Knudsen, Birgitta R.
Publicado 2022

Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds

por Keller, Josephine Geertsen, Petersen, Kamilla Vandsø, Mizielinski, Karol, Thiesen, Celine, Bjergbæk, Lotte, Reguera, Rosa M., Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Trejo, Angela, Masdeu, Carme, Alonso, Concepcion, Knudsen, Birgitta R., Tesauro, Cinzia
Publicado 2023

DNA flowerstructure co-localizes with human pathogens in infected macrophages

por Franch, Oskar, Gutiérrez-Corbo, Camino, Domínguez-Asenjo, Bárbara, Boesen, Thomas, Jensen, Pia Bomholt, Nejsum, Lene N, Keller, Josephine Geertsen, Nielsen, Simon Pagaard, Singh, Prakruti R, Jha, Rajiv Kumar, Nagaraja, Valakunja, Balaña-Fouce, Rafael, Ho, Yi-Ping, Reguera, Rosa María, Knudsen, Birgitta Ruth
Publicado 2020

Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation

por Keller, Josephine Geertsen, Hymøller, Kirstine Mejlstrup, Thorsager, Maria Eriksen, Hansen, Noriko Y, Erlandsen, Jens Uldum, Tesauro, Cinzia, Simonsen, Anne Katrine W, Andersen, Anne Bech, Vandsø Petersen, Kamilla, Holm, Lise Lolle, Stougaard, Magnus, Andresen, Brage Storstein, Kristensen, Peter, Frøhlich, Rikke, Knudsen, Birgitta R
Publicado 2022