Mechanistic Study of the Spiroindolones: A New Class of Antimalarials

por Zou, Bin, Yap, Peiling, Sonntag, Louis-Sebastian, Leong, Seh Yong, Yeung, Bryan K. S., Keller, Thomas H.
Publicado 2012

Discovery of a Non-Peptidic Inhibitor of West Nile Virus NS3 Protease by High-Throughput Docking

por Ekonomiuk, Dariusz, Su, Xun-Cheng, Ozawa, Kiyoshi, Bodenreider, Christophe, Lim, Siew Pheng, Yin, Zheng, Keller, Thomas H., Beer, David, Patel, Viral, Otting, Gottfried, Caflisch, Amedeo, Huang, Danzhi
Publicado 2009

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

por Yeung, Bryan K. S., Zou, Bin, Rottmann, Matthias, Lakshminarayana, Suresh B., Ang, Shi Hua, Leong, Seh Yong, Tan, Jocelyn, Wong, Josephine, Keller-Maerki, Sonja, Fischli, Christoph, Goh, Anne, Schmitt, Esther K., Krastel, Philipp, Francotte, Eric, Kuhen, Kelli, Plouffe, David, Henson, Kerstin, Wagner, Trixie, Winzeler, Elizabeth A., Petersen, Frank, Brun, Reto, Dartois, Veronique, Diagana, Thierry T., Keller, Thomas H.
Publicado 2010

Targeting EYA2 tyrosine phosphatase activity in glioblastoma stem cells induces mitotic catastrophe

por Zhang, Guoxin, Dong, Zhen, Gimple, Ryan C., Wolin, Arthur, Wu, Qiulian, Qiu, Zhixin, Wood, Lisa M., Shen, Jia Z., Jiang, Li, Zhao, Linjie, Lv, Deguan, Prager, Briana C., Kim, Leo J.Y., Wang, Xiuxing, Zhang, Lingdi, Anderson, Ryan L., Moore, Jeffrey K., Bao, Shideng, Keller, Thomas H., Lin, Grace, Kang, Congbao, Hamerlik, Petra, Zhao, Rui, Ford, Heide L., Rich, Jeremy N.
Publicado 2021

A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

por Pethe, Kevin, Sequeira, Patricia C., Agarwalla, Sanjay, Rhee, Kyu, Kuhen, Kelli, Phong, Wai Yee, Patel, Viral, Beer, David, Walker, John R., Duraiswamy, Jeyaraj, Jiricek, Jan, Keller, Thomas H., Chatterjee, Arnab, Tan, Mai Ping, Ujjini, Manjunatha, Rao, Srinivasa P.S., Camacho, Luis, Bifani, Pablo, Mak, Puiying A., Ma, Ida, Barnes, S. Whitney, Chen, Zhong, Plouffe, David, Thayalan, Pamela, Ng, Seow Hwee, Au, Melvin, Lee, Boon Heng, Tan, Bee Huat, Ravindran, Sindhu, Nanjundappa, Mahesh, Lin, Xiuhua, Goh, Anne, Lakshminarayana, Suresh B., Shoen, Carolyn, Cynamon, Michael, Kreiswirth, Barry, Dartois, Veronique, Peters, Eric C., Glynne, Richard, Brenner, Sydney, Dick, Thomas
Publicado 2010