Towards Development of a Non-Toxigenic Clostridioides difficile Oral Spore Vaccine against Toxigenic C. difficile

por Hughes, Jaime, Aston, Carl, Kelly, Michelle L., Griffin, Ruth
Publicado 2022

Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain

por Kuehne, Sarah A., Collery, Mark M., Kelly, Michelle L., Cartman, Stephen T., Cockayne, Alan, Minton, Nigel P.
Publicado 2014

Improving the reproducibility of the NAP1/B1/027 epidemic strain R20291 in the hamster model of infection

por Kelly, Michelle L., Ng, Yen Kuan, Cartman, Stephen T., Collery, Mark M., Cockayne, Alan, Minton, Nigel P.
Publicado 2016

Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against Clostridioides difficile

por Karyal, Cansu, Hughes, Jaime, Kelly, Michelle L., Luckett, Jeni C., Kaye, Philip V., Cockayne, Alan, Minton, Nigel P., Griffin, Ruth
Publicado 2021

What's a SNP between friends: The influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives

por Collery, Mark M., Kuehne, Sarah A., McBride, Shonna M., Kelly, Michelle L., Monot, Marc, Cockayne, Alan, Dupuy, Bruno, Minton, Nigel P.
Publicado 2016

The Role of Flagella in Clostridium difficile Pathogenesis: Comparison between a Non-Epidemic and an Epidemic Strain

por Baban, Soza T., Kuehne, Sarah A., Barketi-Klai, Amira, Cartman, Stephen T., Kelly, Michelle L., Hardie, Kim R., Kansau, Imad, Collignon, Anne, Minton, Nigel P.
Publicado 2013

Characterization of the impact of rpoB mutations on the in vitro and in vivo competitive fitness of Clostridium difficile and susceptibility to fidaxomicin

por Kuehne, Sarah A, Dempster, Andrew W, Collery, Mark M, Joshi, Nimitray, Jowett, Jamie, Kelly, Michelle L, Cave, Rory, Longshaw, Chris M, Minton, Nigel P
Publicado 2018

A roadmap for gene system development in Clostridium

por Minton, Nigel P., Ehsaan, Muhammad, Humphreys, Christopher M., Little, Gareth T., Baker, Jonathan, Henstra, Anne M., Liew, Fungmin, Kelly, Michelle L., Sheng, Lili, Schwarz, Katrin, Zhang, Ying
Publicado 2016

The glucosyltransferase activity of C. difficile Toxin B is required for disease pathogenesis

por Bilverstone, Terry W., Garland, Megan, Cave, Rory J., Kelly, Michelle L., Tholen, Martina, Bouley, Donna M., Kaye, Philip, Minton, Nigel P., Bogyo, Matthew, Kuehne, Sarah A., Melnyk, Roman A.
Publicado 2020

Gene Dosage Effects at the Imprinted Gnas Cluster

por Ball, Simon T., Kelly, Michelle L., Robson, Joan E., Turner, Martin D., Harrison, Jackie, Jones, Lynn, Napper, Diane, Beechey, Colin V., Hough, Tertius, Plagge, Antonius, Cattanach, Bruce M., Cox, Roger D., Peters, Jo
Publicado 2013