Evaluation of assays for drug efficacy in a three-dimensional model of the lung

por Huber, Julia M., Amann, Arno, Koeck, Stefan, Lorenz, Edith, Kelm, Jens M., Obexer, Petra, Zwierzina, Heinz, Gamerith, Gabriele
Publicado 2016

Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model

por Kermanizadeh, Ali, Løhr, Mille, Roursgaard, Martin, Messner, Simon, Gunness, Patrina, Kelm, Jens M, Møller, Peter, Stone, Vicki, Loft, Steffen
Publicado 2014

Therapeutic protein transduction of mammalian cells and mice by nucleic acid-free lentiviral nanoparticles

por Link, Nils, Aubel, Corinne, Kelm, Jens M., Marty, René R., Greber, David, Djonov, Valentin, Bourhis, Jean, Weber, Wilfried, Fussenegger, Martin
Publicado 2006

Integrating Microtissues in Nanofiber Scaffolds for Regenerative Nanomedicine

por Keller, Laetitia, Wagner, Quentin, Offner, Damien, Eap, Sandy, Musset, Anne-Marie, Arruebo, Manuel, Kelm, Jens M., Schwinté, Pascale, Benkirane-Jessel, Nadia
Publicado 2015

Transcriptomic, Proteomic, and Functional Long-Term Characterization of Multicellular Three-Dimensional Human Liver Microtissues

por Messner, Simon, Fredriksson, Lisa, Lauschke, Volker M., Roessger, Katrin, Escher, Claudia, Bober, Magdalena, Kelm, Jens M., Ingelman-Sundberg, Magnus, Moritz, Wolfgang
Publicado 2018

A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment

por Anastasov, Nataša, Höfig, Ines, Radulović, Vanja, Ströbel, Simon, Salomon, Michael, Lichtenberg, Jan, Rothenaigner, Ina, Hadian, Kamyar, Kelm, Jens M., Thirion, Christian, Atkinson, Michael J.
Publicado 2015

Development of a 3D angiogenesis model to study tumour – endothelial cell interactions and the effects of anti-angiogenic drugs

por Amann, Arno, Zwierzina, Marit, Koeck, Stefan, Gamerith, Gabriele, Pechriggl, Elisabeth, Huber, Julia M., Lorenz, Edith, Kelm, Jens M., Hilbe, Wolfgang, Zwierzina, Heinz, Kern, Johann
Publicado 2017

3D-cultivation of NSCLC cell lines induce gene expression alterations of key cancer-associated pathways and mimic in-vivo conditions

por Gamerith, Gabriele, Rainer, Johannes, Huber, Julia M., Hackl, Hubert, Trajanoski, Zlatko, Koeck, Stefan, Lorenz, Edith, Kern, Johann, Kofler, Reinhard, Kelm, Jens M., Zwierzina, Heinz, Amann, Arno
Publicado 2017

A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents

por Herter, Sylvia, Morra, Laura, Schlenker, Ramona, Sulcova, Jitka, Fahrni, Linda, Waldhauer, Inja, Lehmann, Steffi, Reisländer, Timo, Agarkova, Irina, Kelm, Jens M., Klein, Christian, Umana, Pablo, Bacac, Marina
Publicado 2016

Development of an Innovative 3D Cell Culture System to Study Tumour - Stroma Interactions in Non-Small Cell Lung Cancer Cells

por Amann, Arno, Zwierzina, Marit, Gamerith, Gabriele, Bitsche, Mario, Huber, Julia M., Vogel, Georg F., Blumer, Michael, Koeck, Stefan, Pechriggl, Elisabeth J., Kelm, Jens M., Hilbe, Wolfgang, Zwierzina, Heinz
Publicado 2014

Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury

por Proctor, William R., Foster, Alison J., Vogt, Jennifer, Summers, Claire, Middleton, Brian, Pilling, Mark A., Shienson, Daniel, Kijanska, Monika, Ströbel, Simon, Kelm, Jens M., Morgan, Paul, Messner, Simon, Williams, Dominic
Publicado 2017

A model-based assay design to reproduce in vivo patterns of acute drug-induced toxicity

por Kuepfer, Lars, Clayton, Olivia, Thiel, Christoph, Cordes, Henrik, Nudischer, Ramona, Blank, Lars M., Baier, Vanessa, Heymans, Stephane, Caiment, Florian, Roth, Adrian, Fluri, David A., Kelm, Jens M., Castell, José, Selevsek, Nathalie, Schlapbach, Ralph, Keun, Hector, Hynes, James, Sarkans, Ugis, Gmuender, Hans, Herwig, Ralf, Niederer, Steven, Schuchhardt, Johannes, Segall, Matthew, Kleinjans, Jos
Publicado 2017

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of...

por Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S., Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M., Hengstler, Jan G.
Publicado 2013