The Urokinase Plasminogen Activation System in Rheumatoid Arthritis: Pathophysiological Roles and Prospective Therapeutic Targets

por Buckley, Benjamin J., Ali, Umar, Kelso, Michael J., Ranson, Marie
Publicado 2019

Antifungal activity of 6-substituted amiloride and hexamethylene amiloride (HMA) analogs

por Vu, Kiem, Buckley, Benjamin J., Bujaroski, Richard S., Blumwald, Eduardo, Kelso, Michael J., Gelli, Angie
Publicado 2023

Characterization of Five Novel Anti-MRSA Compounds Identified Using a Whole-Animal Caenorhabditis elegans/Galleria mellonella Sequential-Screening Approach

por Khader, Rajamohammed, Tharmalingam, Nagendran, Mishra, Biswajit, Felix, LewisOscar, Ausubel, Frederick M., Kelso, Michael J., Mylonakis, Eleftherios
Publicado 2020

Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

por Serafini, Paolo, Meckel, Kristen, Kelso, Michael, Noonan, Kimberly, Califano, Joseph, Koch, Wayne, Dolcetti, Luigi, Bronte, Vincenzo, Borrello, Ivan
Publicado 2006

Propyl-5-hydroxy-3-methyl-1-phenyl-1H-pyrazole-4-carbodithioate (HMPC): a new bacteriostatic agent against methicillin—resistant Staphylococcus aureus

por Johnston, Tatiana, Van Tyne, Daria, Chen, Roy F., Fawzi, Nicolas L., Kwon, Bumsup, Kelso, Michael J., Gilmore, Michael S., Mylonakis, Eleftherios
Publicado 2018

Screening of 5- and 6-Substituted Amiloride Libraries Identifies Dual-uPA/NHE1 Active and Single Target-Selective Inhibitors

por Buckley, Benjamin J., Kumar, Ashna, Aboelela, Ashraf, Bujaroski, Richard S., Li, Xiuju, Majed, Hiwa, Fliegel, Larry, Ranson, Marie, Kelso, Michael J.
Publicado 2021

Cephalosporin nitric oxide-donor prodrug DEA-C3D disperses biofilms formed by clinical cystic fibrosis isolates of Pseudomonas aeruginosa

por Soren, Odel, Rineh, Ardeshir, Silva, Diogo G, Cai, Yuming, Howlin, Robert P, Allan, Raymond N, Feelisch, Martin, Davies, Jane C, Connett, Gary J, Faust, Saul N, Kelso, Michael J, Webb, Jeremy S
Publicado 2020

6-Furopyridine Hexamethylene Amiloride Is a Non-Selective P2X7 Receptor Antagonist

por Cuthbertson, Peter, Elhage, Amal, Al-Rifai, Dena, Sophocleous, Reece A., Turner, Ross J., Aboelela, Ashraf, Majed, Hiwa, Bujaroski, Richard S., Jalilian, Iman, Kelso, Michael J., Watson, Debbie, Buckley, Benjamin J., Sluyter, Ronald
Publicado 2022

An amiloride derivative is active against the F(1)F(o)-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis

por Hards, Kiel, Cheung, Chen-Yi, Waller, Natalie, Adolph, Cara, Keighley, Laura, Tee, Zhi Shean, Harold, Liam K., Menorca, Ayana, Bujaroski, Richard S., Buckley, Benjamin J., Tyndall, Joel D. A., McNeil, Matthew B., Rhee, Kyu Y., Opel-Reading, Helen K., Krause, Kurt, Preiss, Laura, Langer, Julian D., Meier, Thomas, Hasenoehrl, Erik J., Berney, Michael, Kelso, Michael J., Cook, Gregory M.
Publicado 2022

Low-Dose Nitric Oxide as Targeted Anti-biofilm Adjunctive Therapy to Treat Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis

por Howlin, Robert P., Cathie, Katrina, Hall-Stoodley, Luanne, Cornelius, Victoria, Duignan, Caroline, Allan, Raymond N., Fernandez, Bernadette O., Barraud, Nicolas, Bruce, Ken D., Jefferies, Johanna, Kelso, Michael, Kjelleberg, Staffan, Rice, Scott A., Rogers, Geraint B., Pink, Sandra, Smith, Caroline, Sukhtankar, Priya S., Salib, Rami, Legg, Julian, Carroll, Mary, Daniels, Thomas, Feelisch, Martin, Stoodley, Paul, Clarke, Stuart C., Connett, Gary, Faust, Saul N., Webb, Jeremy S.
Publicado 2017