Obesity-induced miR-802 directly targets AMPK and promotes nonalcoholic steatohepatitis in mice

por Sun, Hao, Seok, Sunmi, Jung, Hyunkyung, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2022

Liver ChIP-seq analysis in FGF19-treated mice reveals SHP as a global transcriptional partner of SREBP-2

por Kim, Young-Chae, Byun, Sangwon, Zhang, Yang, Seok, Sunmi, Kemper, Byron, Ma, Jian, Kemper, Jongsook Kim
Publicado 2015

Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease

por Kim, Young-Chae, Qi, Ming, Dong, Xingchen, Seok, Sunmi, Sun, Hao, Kemper, Byron, Fu, Ting, Kemper, Jongsook Kim
Publicado 2023

Intestinal FGF15/19 physiologically repress hepatic lipogenesis in the late fed-state by activating SHP and DNMT3A

por Kim, Young-Chae, Seok, Sunmi, Zhang, Yang, Ma, Jian, Kong, Bo, Guo, Grace, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2020

Feeding activates FGF15‐SHP‐TFEB‐mediated lipophagy in the gut

por Seok, Sunmi, Kim, Young‐Chae, Zhang, Yang, Kong, Bo, Guo, Grace, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2022

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis

por Kim, Dong-Hyun, Kwon, Sanghoon, Byun, Sangwon, Xiao, Zhen, Park, Sean, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2016

AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle

por Kim, Young-Chae, Seok, Sunmi, Byun, Sangwon, Kong, Bo, Zhang, Yang, Guo, Grace, Xie, Wen, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2018

BRD4 inhibition and FXR activation, individually beneficial in cholestasis, are antagonistic in combination

por Jung, Hyunkyung, Chen, Jinjing, Hu, Xiangming, Sun, Hao, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Kemper, Byron, Chen, Lin-Feng, Kemper, Jongsook Kim
Publicado 2020

Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase

por Byun, Sangwon, Seok, Sunmi, Kim, Young-Chae, Zhang, Yang, Yau, Peter, Iwamori, Naoki, Xu, H. Eric, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2020

Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis

por Byun, Sangwon, Kim, Dong-Hyun, Ryerson, Daniel, Kim, Young-Chae, Sun, Hao, Kong, Bo, Yau, Peter, Guo, Grace, Xu, H. Eric, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2018

Transcriptional regulation of autophagy by an FXR/CREB axis

por Seok, Sunmi, Fu, Ting, Choi, Sung-E, Li, Yang, Zhu, Rong, Kumar, Subodh, Sun, Xiaoxiao, Yoon, Gyesoon, Kang, Yup, Zhong, Wenxuan, Ma, Jian, Kemper, Byron, Kemper, Jongsook Kim
Publicado 2014