Better science for safer medicines: the human imperative

por Archibald, Kathy, Tsaioun, Katya, Kenna, J. Gerry, Pound, Pandora
Publicado 2018

Assessment of gadoxetate DCE-MRI as a biomarker of hepatobiliary transporter inhibition

por Ulloa, Jose L, Stahl, Simone, Yates, James, Woodhouse, Neil, Kenna, J Gerry, Jones, Huw B, Waterton, John C, Hockings, Paul D
Publicado 2013

Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug–Drug Interactions in Rats

por Melillo, Nicola, Scotcher, Daniel, Kenna, J. Gerry, Green, Claudia, Hines, Catherine D. G., Laitinen, Iina, Hockings, Paul D., Ogungbenro, Kayode, Gunwhy, Ebony R., Sourbron, Steven, Waterton, John C., Schuetz, Gunnar, Galetin, Aleksandra
Publicado 2023

Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

por Atienzar, Franck A., Blomme, Eric A., Chen, Minjun, Hewitt, Philip, Kenna, J. Gerry, Labbe, Gilles, Moulin, Frederic, Pognan, Francois, Roth, Adrian B., Suter-Dick, Laura, Ukairo, Okechukwu, Weaver, Richard J., Will, Yvonne, Dambach, Donna M.
Publicado 2016

Can Bile Salt Export Pump Inhibition Testing in Drug Discovery and Development Reduce Liver Injury Risk? An International Transporter Consortium Perspective

por Kenna, J. Gerry, Taskar, Kunal S., Battista, Christina, Bourdet, David L., Brouwer, Kim L.R., Brouwer, Kenneth R., Dai, David, Funk, Christoph, Hafey, Michael J., Lai, Yurong, Maher, Jonathan, Pak, Y. Anne, Pedersen, Jenny M., Polli, Joseph W., Rodrigues, A. David, Watkins, Paul B., Yang, Kyunghee, Yucha, Robert W.
Publicado 2018