Deciphering Combinations of PI3K/AKT/mTOR Pathway Drugs Augmenting Anti-Angiogenic Efficacy In Vivo

por Sasore, Temitope, Kennedy, Breandán
Publicado 2014

Evaluation of the Therapeutic Potential of Histone Deacetylase 6 Inhibitors for Primary and Metastatic Uveal Melanoma

por Sundaramurthi, Husvinee, Giricz, Zoltán, Kennedy, Breandán N.
Publicado 2022

The potential of small molecule brain-derived neurotrophic factor: mimetics to treat inherited retinal degeneration

por Cerquone Perpetuini, Andrea, Mathoux, Justine, Kennedy, Breandán N.
Publicado 2019

Affordable and effective optokinetic response methods to assess visual acuity and contrast sensitivity in larval to juvenile zebrafish

por Gómez Sánchez, Alicia, Álvarez, Yolanda, Colligris, Basilio, Kennedy, Breandán N.
Publicado 2022

Enhancing Understanding of the Visual Cycle by Applying CRISPR/Cas9 Gene Editing in Zebrafish

por Ward, Rebecca, Sundaramurthi, Husvinee, Di Giacomo, Valeria, Kennedy, Breandán N.
Publicado 2018

HDAC6 inhibition by tubastatin A is protective against oxidative stress in a photoreceptor cell line and restores visual function in a zebrafish model of inherited blindness

por Leyk, Janina, Daly, Conor, Janssen-Bienhold, Ulrike, Kennedy, Breandán N, Richter-Landsberg, Christiane
Publicado 2017

Orthogonal Drug Pooling Enhances Phenotype-Based Discovery of Ocular Antiangiogenic Drugs in Zebrafish Larvae

por Ohnesorge, Nils, Sasore, Temitope, Hillary, Daniel, Alvarez, Yolanda, Carey, Michelle, Kennedy, Breandán N.
Publicado 2019

PRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptors

por Morrissey, Maria E, Shelton, Sara, Brockerhoff, Susan E, Hurley, James B, Kennedy, Breandán N
Publicado 2011

Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo

por Moran, Ailis L., Fehilly, John D., Floss Jones, Daniel, Collery, Ross, Kennedy, Breandán N.
Publicado 2022

Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications

por Colucci, Patrizia, Giannaccini, Martina, Baggiani, Matteo, Kennedy, Breandán N., Dente, Luciana, Raffa, Vittoria, Gabellini, Chiara
Publicado 2023

Integrating multiple genome annotation databases improves the interpretation of microarray gene expression data

por Yin, Jun, McLoughlin, Sarah, Jeffery, Ian B, Glaviano, Antonino, Kennedy, Breandan, Higgins, Desmond G
Publicado 2010

Genes and signaling networks regulated during zebrafish optic vesicle morphogenesis

por Yin, Jun, Morrissey, Maria E, Shine, Lisa, Kennedy, Ciarán, Higgins, Desmond G, Kennedy, Breandán N
Publicado 2014

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo

por Merrigan, Stephanie L., Park, Bomina, Ali, Zaheer, Jensen, Lasse D., Corson, Timothy W., Kennedy, Breandán N.
Publicado 2020

Evaluation of Cysteinyl Leukotriene Signaling as a Therapeutic Target for Colorectal Cancer

por Burke, Lorraine, Butler, Clare T., Murphy, Adrian, Moran, Bruce, Gallagher, William M., O'Sullivan, Jacintha, Kennedy, Breandán N.
Publicado 2016

Genetic Deletion of Zebrafish Rab28 Causes Defective Outer Segment Shedding, but Not Retinal Degeneration

por Carter, Stephen P., Moran, Ailís L., Matallanas, David, McManus, Gavin J., Blacque, Oliver E., Kennedy, Breandán N.
Publicado 2020

The Role of Mitochondria in Optic Atrophy With Autosomal Inheritance

por Strachan, Elin L., Mac White-Begg, Delphi, Crean, John, Reynolds, Alison L., Kennedy, Breandán N., O’Sullivan, Niamh C.
Publicado 2021

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours

por Butler, Clare T., Kennedy, Susan A., Buckley, Amy, Doyle, Ronan, Conroy, Emer, Gallagher, William M., O’Sullivan, Jacintha, Kennedy, Breandán N.
Publicado 2019

Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness

por Sundaramurthi, Husvinee, Roche, Sarah L., Grice, Guinevere L., Moran, Ailis, Dillion, Eugene T., Campiani, Giuseppe, Nathan, James A., Kennedy, Breandán N.
Publicado 2020

GATD3A, a mitochondrial deglycase with evolutionary origins from gammaproteobacteria, restricts the formation of advanced glycation end products

por Smith, Andrew J., Advani, Jayshree, Brock, Daniel C., Nellissery, Jacob, Gumerson, Jessica, Dong, Lijin, Aravind, L., Kennedy, Breandán, Swaroop, Anand
Publicado 2022

A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy

por Sulaiman, Rania S., Merrigan, Stephanie, Quigley, Judith, Qi, Xiaoping, Lee, Bit, Boulton, Michael E., Kennedy, Breandán, Seo, Seung-Yong, Corson, Timothy W.
Publicado 2016