The Impact of Macrophage Nucleotide Pools on HIV-1 Reverse Transcription, Viral Replication, and the Development of Novel Antiviral Agents

por Gavegnano, Christina, Kennedy, Edward M., Kim, Baek, Schinazi, Raymond F.
Publicado 2012

Differential RISC association of endogenous human microRNAs predicts their inhibitory potential

por Flores, Omar, Kennedy, Edward M., Skalsky, Rebecca L., Cullen, Bryan R.
Publicado 2014

Influenza A virus-derived siRNAs increase in the absence of NS1 yet fail to inhibit virus replication

por Tsai, Kevin, Courtney, David G., Kennedy, Edward M., Cullen, Bryan R.
Publicado 2018

Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity

por Bogerd, Hal P., Kennedy, Edward M., Whisnant, Adam W., Cullen, Bryan R.
Publicado 2017

Partial reconstitution of the RNAi response in human cells using Drosophila gene products

por Kennedy, Edward M., Kornepati, Anand V.R., Bogerd, Hal P., Cullen, Bryan R.
Publicado 2017

Targeting HPV16 DNA using CRISPR/Cas inhibits anal cancer growth in vivo

por Hsu, David S, Kornepati, Anand VR, Glover, Wayne, Kennedy, Edward M, Cullen, Bryan R
Publicado 2018

Derivation and characterization of Dicer- and microRNA-deficient human cells

por Bogerd, Hal P., Whisnant, Adam W., Kennedy, Edward M., Flores, Omar, Cullen, Bryan R.
Publicado 2014

Epitranscriptomic addition of m(6)A regulates HIV-1 RNA stability and alternative splicing

por Tsai, Kevin, Bogerd, Hal P., Kennedy, Edward M., Emery, Ann, Swanstrom, Ronald, Cullen, Bryan R.
Publicado 2021

Expression of CRISPR/Cas single guide RNAs using small tRNA promoters

por Mefferd, Adam L., Kornepati, Anand V.R., Bogerd, Hal P., Kennedy, Edward M., Cullen, Bryan R.
Publicado 2015

Ribonucleoside Triphosphates as Substrate of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Human Macrophages

por Kennedy, Edward M., Gavegnano, Christina, Nguyen, Laura, Slater, Rebecca, Lucas, Amanda, Fromentin, Emilie, Schinazi, Raymond F., Kim, Baek
Publicado 2010

Extensive Epitranscriptomic Methylation of A and C Residues on Murine Leukemia Virus Transcripts Enhances Viral Gene Expression

por Courtney, David G., Chalem, Andrea, Bogerd, Hal P., Law, Brittany A., Kennedy, Edward M., Holley, Christopher L., Cullen, Bryan R.
Publicado 2019

Seneca Valley virus replicons are packaged in trans and have the capacity to overcome the limitations of viral transgene expression

por Bryant, Jeffrey D., Lee, Jennifer S., De Almeida, Ana, Jacques, Judy, Chang, Ching-Hung, Fassler, William, Quéva, Christophe, Lerner, Lorena, Kennedy, Edward M.
Publicado 2023

Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications

por Friedland, Ari E., Baral, Reshica, Singhal, Pankhuri, Loveluck, Katherine, Shen, Shen, Sanchez, Minerva, Marco, Eugenio, Gotta, Gregory M., Maeder, Morgan L., Kennedy, Edward M., Kornepati, Anand V. R., Sousa, Alexander, Collins, McKensie A., Jayaram, Hari, Cullen, Bryan R., Bumcrot, David
Publicado 2015

Design of an Interferon-Resistant Oncolytic HSV-1 Incorporating Redundant Safety Modalities for Improved Tolerability

por Kennedy, Edward M., Farkaly, Terry, Grzesik, Peter, Lee, Jennifer, Denslow, Agnieszka, Hewett, Jacqueline, Bryant, Jeffrey, Behara, Prajna, Goshert, Caitlin, Wambua, Daniel, De Almeida, Ana, Jacques, Judith, Deavall, Damian, Rottman, James B., Glorioso, Joseph C., Finer, Mitchell H., Haines, Brian B., Quéva, Christophe, Lerner, Lorena
Publicado 2020

N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection

por Gokhale, Nandan S., McIntyre, Alexa B.R., McFadden, Michael J., Roder, Allison E., Kennedy, Edward M., Gandara, Jorge A., Hopcraft, Sharon E., Quicke, Kendra M., Vazquez, Christine, Willer, Jason, Ilkayeva, Olga R., Law, Brittany A., Holley, Christopher L., Garcia-Blanco, Mariano A., Evans, Matthew J., Suthar, Mehul S., Bradrick, Shelton S., Mason, Christopher E., Horner, Stacy M.
Publicado 2016

Development of intravenously administered synthetic RNA virus immunotherapy for the treatment of cancer

por Kennedy, Edward M., Denslow, Agnieszka, Hewett, Jacqueline, Kong, Lingxin, De Almeida, Ana, Bryant, Jeffrey D., Lee, Jennifer S., Jacques, Judy, Feau, Sonia, Hayes, Melissa, McMichael, Elizabeth L., Wambua, Daniel, Farkaly, Terry, Rahmeh, Amal A, Herschelman, Lauren, Douglas, Danielle, Spinale, Jacob, Adhikari, Sanmit, Deterling, Jessica, Scott, Matt, Haines, Brian B., Finer, Mitchell H., Ashburn, Ted T, Quéva, Christophe, Lerner, Lorena
Publicado 2022