Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI

por Kennedy, Madison A, Hosford, Christopher J, Azumaya, Caleigh M, Luyten, Yvette A, Chen, Minyong, Morgan, Richard D, Stoddard, Barry L
Publicado 2023

Design of functionalised circular tandem repeat proteins with longer repeat topologies and enhanced subunit contact surfaces

por Hallinan, Jazmine P., Doyle, Lindsey A., Shen, Betty W., Gewe, Mesfin M., Takushi, Brittany, Kennedy, Madison A., Friend, Della, Roberts, James M., Bradley, Philip, Stoddard, Barry L.
Publicado 2021

De novo design of protein homodimers containing tunable symmetric protein pockets

por Hicks, Derrick R., Kennedy, Madison A., Thompson, Kirsten A., DeWitt, Michelle, Coventry, Brian, Kang, Alex, Bera, Asim K., Brunette, T. J., Sankaran, Banumathi, Stoddard, Barry, Baker, David
Publicado 2022

Stepwise design of pseudosymmetric protein hetero-oligomers

por Kibler, Ryan D., Lee, Sangmin, Kennedy, Madison A., Wicky, Basile I. M., Lai, Stella M., Kostelic, Marius M., Li, Xinting, Chow, Cameron M., Carter, Lauren, Wysocki, Vicki H., Stoddard, Barry L., Baker, David
Publicado 2023

Structural basis for isoform-specific inhibition of human CTPS1

por Lynch, Eric M., DiMattia, Michael A., Albanese, Steven, van Zundert, Gydo C. P., Hansen, Jesse M., Quispe, Joel D., Kennedy, Madison A., Verras, Andreas, Borrelli, Kenneth, Toms, Angela V., Kaila, Neelu, Kreutter, Kevin D., McElwee, Joshua J., Kollman, Justin M.
Publicado 2021