BEX1 is a critical determinant of viral myocarditis

por Martens, Colton R., Dorn, Lisa E., Kenney, Adam D., Bansal, Shyam S., Yount, Jacob S., Accornero, Federica
Publicado 2022

From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections

por Chemudupati, Mahesh, Kenney, Adam D., Bonifati, Serena, Zani, Ashley, McMichael, Temet M., Wu, Li, Yount, Jacob S.
Publicado 2019

The host antiviral protein SAMHD1 suppresses NF-κB activation by interacting with the IKK complex during inflammatory responses and viral infection

por Yang, Hua, Espada, Constanza E., Phillips, Stacia, Martinez, Nicholas, Kenney, Adam D., Yount, Jacob S., Xiong, Yong, Wu, Li
Publicado 2023

SARS-CoV-2 Nsp14 activates NF-κB signaling and induces IL-8 upregulation

por Li, Taiwei, Kenney, Adam D., Liu, Helu, Fiches, Guillaume N., Zhou, Dawei, Biswas, Ayan, Que, Jianwen, Santoso, Netty, Yount, Jacob S., Zhu, Jian
Publicado 2021

Inhibiting the Deubiquitinase UCHL1 Reduces SARS-CoV-2 Viral Uptake by ACE2

por Bednash, Joseph S., Johns, Finny, Farkas, Daniela, Elhance, Ajit, Adair, Jessica, Cress, Kirstin, Yount, Jacob S., Kenney, Adam D., Londino, James D., Mallampalli, Rama K.
Publicado 2023

SAMHD1 impairs type I interferon induction through the MAVS, IKKε, and IRF7 signaling axis during viral infection

por Espada, Constanza E., Sari, Levent, Cahill, Michael P., Yang, Hua, Phillips, Stacia, Martinez, Nicholas, Kenney, Adam D., Yount, Jacob S., Xiong, Yong, Lin, Milo M., Wu, Li
Publicado 2023

Opposing activities of IFITM proteins in SARS‐CoV‐2 infection

por Shi, Guoli, Kenney, Adam D, Kudryashova, Elena, Zani, Ashley, Zhang, Lizhi, Lai, Kin Kui, Hall‐Stoodley, Luanne, Robinson, Richard T, Kudryashov, Dmitri S, Compton, Alex A, Yount, Jacob S
Publicado 2020

MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

por Sermersheim, Matthew, Kenney, Adam D., Lin, Pei-Hui, McMichael, Temet M., Cai, Chuanxi, Gumpper, Kristyn, Adesanya, T. M. Ayodele, Li, Haichang, Zhou, Xinyu, Park, Ki-Ho, Yount, Jacob S., Ma, Jianjie
Publicado 2020

Innate immune control of influenza virus interspecies adaptation

por Denz, Parker J., Speaks, Samuel, Kenney, Adam D., Eddy, Adrian C., Papa, Jonathan L., Roettger, Jack, Scace, Sydney C., Hemann, Emily A., Forero, Adriana, Webby, Richard J., Bowman, Andrew S., Yount, Jacob S.
Publicado 2023

RETRACTED ARTICLE: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection

por Laliotis, Georgios I., Kenney, Adam D., Chavdoula, Evangelia, Orlacchio, Arturo, Kaba, Abdul, La Ferlita, Alessandro, Anastas, Vollter, Tsatsanis, Christos, Beane, Joal D., Sehgal, Lalit, Coppola, Vincenzo, Yount, Jacob S., Tsichlis, Philip N.
Publicado 2021

Retraction Note: Phosphor-IWS1-dependent U2AF2 splicing regulates trafficking of CAR-E-positive intronless gene mRNAs and sensitivity to viral infection

por Laliotis, Georgios I., Kenney, Adam D., Chavdoula, Evangelia, Orlacchio, Arturo, Kaba, Abdul, La Ferlita, Alessandro, Anastas, Vollter, Tsatsanis, Christos, Beane, Joal D., Sehgal, Lalit, Coppola, Vincenzo, Yount, Jacob S., Tsichlis, Philip N.
Publicado 2021

SARS-CoV-2 Nsp14 protein associates with IMPDH2 and activates NF-κB signaling

por Li, Tai-Wei, Kenney, Adam D., Park, Jun-Gyu, Fiches, Guillaume N., Liu, Helu, Zhou, Dawei, Biswas, Ayan, Zhao, Weiqiang, Que, Jianwen, Santoso, Netty, Martinez-Sobrido, Luis, Yount, Jacob S., Zhu, Jian
Publicado 2022

Rapalogs downmodulate intrinsic immunity and promote cell entry of SARS-CoV-2

por Shi, Guoli, Chiramel, Abhilash I., Li, Tiansheng, Lai, Kin Kui, Kenney, Adam D., Zani, Ashley, Eddy, Adrian C., Majdoul, Saliha, Zhang, Lizhi, Dempsey, Tirhas, Beare, Paul A., Kar, Swagata, Yewdell, Jonathan W., Best, Sonja M., Yount, Jacob S., Compton, Alex A.
Publicado 2022

Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice

por Kenney, Adam D, Zani, Ashley, Kawahara, Jeffrey, Eddy, Adrian C, Wang, Xiao‐Liang, Mahesh, KC, Lu, Mijia, Thomas, Jeronay, Kohlmeier, Jacob E, Suthar, Mehul S, Hemann, Emily A, Li, Jianrong, Peeples, Mark E, Hall‐Stoodley, Luanne, Forero, Adriana, Cai, Chuanxi, Ma, Jianjie, Yount, Jacob S
Publicado 2023

Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis

por Kenney, Adam D., Aron, Stephanie L., Gilbert, Clara, Kumar, Naresh, Chen, Peng, Eddy, Adrian, Zhang, Lizhi, Zani, Ashley, Vargas-Maldonado, Nahara, Speaks, Samuel, Kawahara, Jeffrey, Denz, Parker J., Dorn, Lisa, Accornero, Federica, Ma, Jianjie, Zhu, Hua, Rajaram, Murugesan V. S., Cai, Chuanxi, Langlois, Ryan A., Yount, Jacob S.
Publicado 2022

Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis

por Eltobgy, Mostafa M., Zani, Ashley, Kenney, Adam D., Estfanous, Shady, Kim, Eunsoo, Badr, Asmaa, Carafice, Cierra, Daily, Kylene, Whitham, Owen, Pietrzak, Maciej, Webb, Amy, Kawahara, Jeffrey, Eddy, Adrian C., Denz, Parker, Lu, Mijia, Mahesh, KC, Peeples, Mark E., Li, Jianrong, Zhu, Jian, Que, Jianwen, Robinson, Richard, Mejia, Oscar Rosas, Rayner, Rachael E., Hall-Stoodley, Luanne, Seveau, Stephanie, Gavrilin, Mikhail A., Zhang, Xiaoli, Thomas, Jeronay, Kohlmeier, Jacob E., Suthar, Mehul S., Oltz, Eugene, Tedeschi, Andrea, Robledo-Avila, Frank H., Partida-Sanchez, Santiago, Hemann, Emily A., Abdelrazik, Eman, Forero, Adriana, Nimjee, Shahid M., Boyaka, Prosper N., Cormet-Boyaka, Estelle, Yount, Jacob S., Amer, Amal O.
Publicado 2022