Sema3A Antibody BI-X Prevents Cell Permeability and Cytoskeletal Collapse in HRMECs and Increases Tip Cell Density in Mouse Oxygen-Induced Retinopathy

por Zippel, Nina, Kenny, Cynthia Hess, Wu, Helen, Garneau, Michel, Kroe-Barrett, Rachel, Gupta, Priyanka, Low, Sarah, Bakker, Remko A., Thomas, Leo
Publicado 2022

AAV-mediated expression of a new conformational anti-aggregated α-synuclein antibody prolongs survival in a genetic model of α-synucleinopathies

por Düchs, Matthias, Blazevic, Dragica, Rechtsteiner, Philipp, Kenny, Cynthia, Lamla, Thorsten, Low, Sarah, Savistchenko, Jimmy, Neumann, Manuela, Melki, Ronald, Schönberger, Tanja, Stierstorfer, Birgit, Wyatt, David, Igney, Frederik, Ciossek, Thomas
Publicado 2023

Development of novel ultra-sensitive IL-11 target engagement assays to support mechanistic PK/PD modeling for an anti-IL-11 antibody therapeutic

por Myzithras, Maria, Lin, Siqi, Radden, Legairre, Hess Kenny, Cynthia, Cai, Zheng, MacDonald, Angus, Binetti, Ralph, Marlow, Michael, Fracasso, Paul, Gibson, Glenn, Bartlett, Christina, Hawkins, Julie, Hansel, Steven
Publicado 2022

Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn

por Yang, Danlin, Giragossian, Craig, Castellano, Steven, Lasaro, Marcio, Xiao, Haiguang, Saraf, Himanshu, Hess Kenny, Cynthia, Rybina, Irina, Huang, Zhong-Fu, Ahlberg, Jennifer, Bigwarfe, Tammy, Myzithras, Maria, Waltz, Erica, Roberts, Simon, Kroe-Barrett, Rachel, Singh, Sanjaya
Publicado 2017

Combination of two novel blocking antibodies, anti-PD-1 antibody ezabenlimab (BI 754091) and anti-LAG-3 antibody BI 754111, leads to increased immune cell responses

por Zettl, Markus, Wurm, Melanie, Schaaf, Otmar, Mostböck, Sven, Tirapu, Iñigo, Apfler, Ilse, Lorenz, Ivo C., Frego, Lee, Kenny, Cynthia, Thibodeau, Michael, Oquendo Cifuentes, Elisa, Reschke, Markus, Moll, Jürgen, Kraut, Norbert, Vogt, Anne, Sedgwick, Jonathon D., Waizenegger, Irene C.
Publicado 2022