Visualization of sympathetic neural innervation in human white adipose tissue

por Perdikari, Aliki, Cacciottolo, Tessa, Henning, Elana, Mendes de Oliveira, Edson, Keogh, Julia M., Farooqi, I. Sadaf
Publicado 2022

A Metabolomic Signature of Acute Caloric Restriction

por Collet, Tinh-Hai, Sonoyama, Takuhiro, Henning, Elana, Keogh, Julia M., Ingram, Brian, Kelway, Sarah, Guo, Lining, Farooqi, I. Sadaf
Publicado 2017

Oxytocin administration suppresses hypothalamic activation in response to visual food cues

por van der Klaauw, Agatha A., Ziauddeen, Hisham, Keogh, Julia M., Henning, Elana, Dachi, Sekesai, Fletcher, Paul C., Farooqi, I. Sadaf
Publicado 2017

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila

por Agrawal, Neha, Lawler, Katherine, Davidson, Catherine M., Keogh, Julia M., Legg, Robert, Barroso, Inês, Farooqi, I. Sadaf, Brand, Andrea H.
Publicado 2021

Leptin-Mediated Changes in the Human Metabolome

por Lawler, Katherine, Huang-Doran, Isabel, Sonoyama, Takuhiro, Collet, Tinh-Hai, Keogh, Julia M, Henning, Elana, O’Rahilly, Stephen, Bottolo, Leonardo, Farooqi, I Sadaf
Publicado 2020

Obesity-Associated Melanocortin-4 Receptor Mutations Are Associated With Changes in the Brain Response to Food Cues

por van der Klaauw, Agatha A., von dem Hagen, Elisabeth A. H., Keogh, Julia M., Henning, Elana, O'Rahilly, Stephen, Lawrence, Andrew D., Calder, Andrew J., Farooqi, I. Sadaf
Publicado 2014

Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

por van der Klaauw, Agatha A., Keogh, Julia M., Henning, Elana, Stephenson, Cheryl, Kelway, Sarah, Trowse, Victoria M., Subramanian, Naresh, O'Rahilly, Stephen, Fletcher, Paul C., Farooqi, I. Sadaf
Publicado 2016

Neural networks associated with body composition in frontotemporal dementia

por Ahmed, Rebekah M., Landin‐Romero, Ramon, Liang, Cheng T., Keogh, Julia M., Henning, Elana, Strikwerda‐Brown, Cherie, Devenney, Emma M., Hodges, John R., Kiernan, Matthew C., Farooqi, I. Sadaf, Piguet, Olivier
Publicado 2019

Failure of sucrose replacement with the non-nutritive sweetener erythritol to alter GLP-1 or PYY release or test meal size in lean or obese people

por Overduin, Joost, Collet, Tinh-Hai, Medic, Nenad, Henning, Elana, Keogh, Julia M., Forsyth, Faye, Stephenson, Cheryl, Kanning, Marja W., Ruijschop, Rianne M.A.J., Farooqi, I. Sadaf, van der Klaauw, Agatha A.
Publicado 2016

Genetic architecture of human thinness compared to severe obesity

por Riveros-McKay, Fernando, Mistry, Vanisha, Bounds, Rebecca, Hendricks, Audrey, Keogh, Julia M., Thomas, Hannah, Henning, Elana, Corbin, Laura J., O’Rahilly, Stephen, Zeggini, Eleftheria, Wheeler, Eleanor, Barroso, Inês, Farooqi, I. Sadaf
Publicado 2019

A Transcriptomic Signature of the Hypothalamic Response to Fasting and BDNF Deficiency in Prader-Willi Syndrome

por Bochukova, Elena G., Lawler, Katherine, Croizier, Sophie, Keogh, Julia M., Patel, Nisha, Strohbehn, Garth, Lo, Kitty K., Humphrey, Jack, Hokken-Koelega, Anita, Damen, Layla, Donze, Stephany, Bouret, Sebastien G., Plagnol, Vincent, Farooqi, I. Sadaf
Publicado 2018

Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene

por Wabitsch, Martin, Funcke, Jan-Bernd, von Schnurbein, Julia, Denzer, Friederike, Lahr, Georgia, Mazen, Inas, El-Gammal, Mona, Denzer, Christian, Moss, Anja, Debatin, Klaus-Michael, Gierschik, Peter, Mistry, Vanisha, Keogh, Julia M., Farooqi, I. Sadaf, Moepps, Barbara, Fischer-Posovszky, Pamela
Publicado 2015

Functional Characterization of Obesity-Associated Variants Involving the α and β Isoforms of Human SH2B1

por Pearce, Laura R., Joe, Ray, Doche, Michael E., Su, Hsiao-Wen, Keogh, Julia M., Henning, Elana, Argetsinger, Lawrence S., Bochukova, Elena G., Cline, Joel M., Garg, Sumedha, Saeed, Sadia, Shoelson, Steven, O'Rahilly, Stephen, Barroso, Inês, Rui, Liangyou, Farooqi, I. Sadaf, Carter-Su, Christin
Publicado 2014

Human BDNF/TrkB variants impair hippocampal synaptogenesis and associate with neurobehavioural abnormalities

por Sonoyama, Takuhiro, Stadler, Lukas K. J., Zhu, Mingyan, Keogh, Julia M., Henning, Elana, Hisama, Fuki, Kirwan, Peter, Jura, Magdalena, Blaszczyk, Beata K., DeWitt, David C., Brouwers, Bas, Hyvönen, Marko, Barroso, Inês, Merkle, Florian T., Appleyard, Suzanne M., Wayman, Gary A., Farooqi, I. Sadaf
Publicado 2020

Obesity Due to Steroid Receptor Coactivator-1 Deficiency Is Associated With Endocrine and Metabolic Abnormalities

por Cacciottolo, Tessa M, Henning, Elana, Keogh, Julia M, Bel Lassen, Pierre, Lawler, Katherine, Bounds, Rebecca, Ahmed, Rachel, Perdikari, Aliki, Mendes de Oliveira, Edson, Smith, Miriam, Godfrey, Edmund M, Johnson, Elspeth, Hodson, Leanne, Clément, Karine, van der Klaauw, Agatha A, Farooqi, I Sadaf
Publicado 2022

A rare human variant that disrupts GPR10 signalling causes weight gain in mice

por Talbot, Fleur, Feetham, Claire H., Mokrosiński, Jacek, Lawler, Katherine, Keogh, Julia M., Henning, Elana, Mendes de Oliveira, Edson, Ayinampudi, Vikram, Saeed, Sadia, Bonnefond, Amélie, Arslan, Mohammed, Yeo, Giles S. H., Froguel, Philippe, Bechtold, David A., Adamson, Antony, Humphreys, Neil, Barroso, Inês, Luckman, Simon M., Farooqi, I. Sadaf
Publicado 2023

Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation

por Brouwers, Bas, de Oliveira, Edson Mendes, Marti-Solano, Maria, Monteiro, Fabiola B.F., Laurin, Suli-Anne, Keogh, Julia M., Henning, Elana, Bounds, Rebecca, Daly, Carole A., Houston, Shane, Ayinampudi, Vikram, Wasiluk, Natalia, Clarke, David, Plouffe, Bianca, Bouvier, Michel, Babu, M. Madan, Farooqi, I. Sadaf, Mokrosiński, Jacek
Publicado 2021

Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription

por Marenne, Gaëlle, Hendricks, Audrey E., Perdikari, Aliki, Bounds, Rebecca, Payne, Felicity, Keogh, Julia M., Lelliott, Christopher J., Henning, Elana, Pathan, Saad, Ashford, Sofie, Bochukova, Elena G., Mistry, Vanisha, Daly, Allan, Hayward, Caroline, Wareham, Nicholas J., O’Rahilly, Stephen, Langenberg, Claudia, Wheeler, Eleanor, Zeggini, Eleftheria, Farooqi, I. Sadaf, Barroso, Inês
Publicado 2020

Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance

por Flores, Anabel, Argetsinger, Lawrence S., Stadler, Lukas K.J., Malaga, Alvaro E., Vander, Paul B., DeSantis, Lauren C., Joe, Ray M., Cline, Joel M., Keogh, Julia M., Henning, Elana, Barroso, Ines, Mendes de Oliveira, Edson, Chandrashekar, Gowri, Clutter, Erik S., Hu, Yixin, Stuckey, Jeanne, Farooqi, I. Sadaf, Myers, Martin G., Carter-Su, Christin
Publicado 2019

Leptin Mediates the Increase in Blood Pressure Associated with Obesity

por Simonds, Stephanie E., Pryor, Jack T., Ravussin, Eric, Greenway, Frank L., Dileone, Ralph, Allen, Andrew M., Bassi, Jaspreet, Elmquist, Joel K., Keogh, Julia M., Henning, Elana, Myers, Martin G., Licinio, Julio, Brown, Russell D., Enriori, Pablo J., O’Rahilly, Stephen, Sternson, Scott M., Grove, Kevin L., Spanswick, David C., Farooqi, I. Sadaf, Cowley, Michael A.
Publicado 2014