Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein

por Whitehead, Jack D., Grimes, Jonathan M., Keown, Jeremy R.
Publicado 2023

Characterisation of assembly and ubiquitylation by the RBCC motif of Trim5α

por Keown, Jeremy R., Yang, Joy X., Douglas, Jordan, Goldstone, David C.
Publicado 2016

The SARS-CoV-2 RNA polymerase is a viral RNA capping enzyme

por Walker, Alexander P, Fan, Haitian, Keown, Jeremy R, Knight, Michael L, Grimes, Jonathan M, Fodor, Ervin
Publicado 2021

The C-Terminal Domains of the PB2 Subunit of the Influenza A Virus RNA Polymerase Directly Interact with Cellular GTPase Rab11a

por Veler, Hana, Fan, Haitian, Keown, Jeremy R., Sharps, Jane, Fournier, Marjorie, Grimes, Jonathan M., Fodor, Ervin
Publicado 2022

Structure of an H3N2 influenza virus nucleoprotein

por Knight, Michael L., Fan, Haitian, Bauer, David L. V., Grimes, Jonathan M., Fodor, Ervin, Keown, Jeremy R.
Publicado 2021

Enisamium is a small molecule inhibitor of the influenza A virus and SARS-CoV-2 RNA polymerases

por Walker, Alexander P, Fan, Haitian, Keown, Jeremy R, Margitich, Victor, Grimes, Jonathan M, Fodor, Ervin, te Velthuis, Aartjan J W
Publicado 2020

Structural Analysis of the Menangle Virus P Protein Reveals a Soft Boundary between Ordered and Disordered Regions

por Webby, Melissa N., Herr, Nicole, Bulloch, Esther M. M., Schmitz, Michael, Keown, Jeremy R., Goldstone, David C., Kingston, Richard L.
Publicado 2021

Host ANP32A mediates the assembly of the influenza virus replicase

por Carrique, Loïc, Fan, Haitian, Walker, Alexander P, Keown, Jeremy R, Sharps, Jane, Staller, Ecco, Barclay, Wendy S, Fodor, Ervin, Grimes, Jonathan M
Publicado 2020

A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins

por Keown, Jeremy R., Black, Moyra M., Ferron, Aaron, Yap, Melvyn, Barnett, Michael J., Pearce, F. Grant, Stoye, Jonathan P., Goldstone, David C.
Publicado 2018

The Protozoan Trichomonas vaginalis Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases

por Pinheiro, Jully, Biboy, Jacob, Vollmer, Waldemar, Hirt, Robert P., Keown, Jeremy R., Artuyants, Anastasiia, Black, Moyra M., Goldstone, David C., Simoes-Barbosa, Augusto
Publicado 2018

Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies

por Keown, Jeremy R., Zhu, Zihan, Carrique, Loïc, Fan, Haitian, Walker, Alexander P., Serna Martin, Itziar, Pardon, Els, Steyaert, Jan, Fodor, Ervin, Grimes, Jonathan M.
Publicado 2022

NlpC/P60 peptidoglycan hydrolases of Trichomonas vaginalis have complementary activities that empower the protozoan to control host-protective lactobacilli

por Barnett, Michael J., Pinheiro, Jully, Keown, Jeremy R., Biboy, Jacob, Gray, Joe, Lucinescu, Ioana-Wilhelmina, Vollmer, Waldemar, Hirt, Robert P., Simoes-Barbosa, Augusto, Goldstone, David C.
Publicado 2023

Influenza A virus RNA polymerase structures provide insights into viral genome replication

por Fan, Haitian, Walker, Alexander P, Carrique, Loïc, Keown, Jeremy R, Martin, Itziar Serna, Karia, Dimple, Sharps, Jane, Hengrung, Narin, Pardon, Els, Steyaert, Jan, Grimes, Jonathan M, Fodor, Ervin
Publicado 2019

Flavivirus maturation leads to the formation of an occupied lipid pocket in the surface glycoproteins

por Renner, Max, Dejnirattisai, Wanwisa, Carrique, Loïc, Martin, Itziar Serna, Karia, Dimple, Ilca, Serban L., Ho, Shu F., Kotecha, Abhay, Keown, Jeremy R., Mongkolsapaya, Juthathip, Screaton, Gavin R., Grimes, Jonathan M.
Publicado 2021

Atomic structure of a nudivirus occlusion body protein determined from a 70-year-old crystal sample

por Keown, Jeremy R., Crawshaw, Adam D., Trincao, Jose, Carrique, Loïc, Gildea, Richard J., Horrell, Sam, Warren, Anna J., Axford, Danny, Owen, Robin, Evans, Gwyndaf, Bézier, Annie, Metcalf, Peter, Grimes, Jonathan M.
Publicado 2023

Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix

por Oliver, Michael R., Horne, Christopher R., Shrestha, Safal, Keown, Jeremy R., Liang, Lung-Yu, Young, Samuel N., Sandow, Jarrod J., Webb, Andrew I., Goldstone, David C., Lucet, Isabelle S., Kannan, Natarajan, Metcalf, Peter, Murphy, James M.
Publicado 2021

Characterization of the SARS-CoV-2 ExoN (nsp14(ExoN)–nsp10) complex: implications for its role in viral genome stability and inhibitor identification

por Baddock, Hannah T, Brolih, Sanja, Yosaatmadja, Yuliana, Ratnaweera, Malitha, Bielinski, Marcin, Swift, Lonnie P, Cruz-Migoni, Abimael, Fan, Haitian, Keown, Jeremy R, Walker, Alexander P, Morris, Garrett M, Grimes, Jonathan M, Fodor, Ervin, Schofield, Christopher J, Gileadi, Opher, McHugh, Peter J
Publicado 2022