Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7–Lin28 RNA–Protein Interaction

por Lorenz, Daniel A., Kaur, Tanpreet, Kerk, Samuel A., Gallagher, Erin E., Sandoval, Jorge, Garner, Amanda L.
Publicado 2018

Spotlight on GOT2 in Cancer Metabolism

por Kerk, Samuel A, Garcia-Bermudez, Javier, Birsoy, Kivanc, Sherman, Mara H, Shah, Yatrik M, Lyssiotis, Costas A
Publicado 2023

Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption

por Zhu, Lingxin, Tang, Yi, Li, Xiao-Yan, Kerk, Samuel A., Lyssiotis, Costas A., Sun, Xiaoyue, Wang, Zijun, Cho, Jung-Sun, Ma, Jun, Weiss, Stephen J.
Publicado 2023

The human type 2 diabetes-specific visceral adipose tissue proteome and transcriptome in obesity

por Carruthers, Nicholas J., Strieder-Barboza, Clarissa, Caruso, Joseph A., Flesher, Carmen G., Baker, Nicki A., Kerk, Samuel A., Ky, Alexander, Ehlers, Anne P., Varban, Oliver A., Lyssiotis, Costas A., Lumeng, Carey N., Stemmer, Paul M., O’Rourke, Robert W.
Publicado 2021

A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling

por Zhu, Lingxin, Tang, Yi, Li, Xiao‐Yan, Kerk, Samuel A, Lyssiotis, Costas A, Feng, Wenqing, Sun, Xiaoyue, Hespe, Geoffrey E, Wang, Zijun, Stemmler, Marc P, Brabletz, Simone, Brabletz, Thomas, Keller, Evan T, Ma, Jun, Cho, Jung‐Sun, Yang, Jingwen, Weiss, Stephen J
Publicado 2023

Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells.

por Schwartz, Andrew J., Goyert, Joshua W., Solanki, Sumeet, Kerk, Samuel A., Chen, Brandon, Castillo, Cristina, Hsu, Peggy P., Do, Brian T., Singhal, Rashi, Dame, Michael K., Lee, Ho-Joon, Spence, Jason R., Lakhal-Littleton, Samira, Vander Heiden, Matthew G., Lyssiotis, Costas A., Xue, Xiang, Shah, Yatrik M.
Publicado 2021

Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress

por Devenport, Samantha N., Singhal, Rashi, Radyk, Megan D., Taranto, Joseph G., Kerk, Samuel A., Chen, Brandon, Goyert, Joshua W., Jain, Chesta, Das, Nupur K., Oravecz-Wilson, Katherine, Zhang, Li, Greenson, Joel K., Chen, Y. Eugene, Soleimanpour, Scott A., Reddy, Pavan, Lyssiotis, Costas A., Shah, Yatrik M.
Publicado 2021

Hyaluronic acid fuels pancreatic cancer cell growth

por Kim, Peter K, Halbrook, Christopher J, Kerk, Samuel A, Radyk, Megan, Wisner, Stephanie, Kremer, Daniel M, Sajjakulnukit, Peter, Andren, Anthony, Hou, Sean W, Trivedi, Ayush, Thurston, Galloway, Anand, Abhinav, Yan, Liang, Salamanca-Cardona, Lucia, Welling, Samuel D, Zhang, Li, Pratt, Matthew R, Keshari, Kayvan R, Ying, Haoqiang, Lyssiotis, Costas A
Publicado 2021

Extrinsic KRAS Signaling Shapes the Pancreatic Microenvironment Through Fibroblast Reprogramming

por Velez-Delgado, Ashley, Donahue, Katelyn L., Brown, Kristee L., Du, Wenting, Irizarry-Negron, Valerie, Menjivar, Rosa E., Lasse Opsahl, Emily L., Steele, Nina G., The, Stephanie, Lazarus, Jenny, Sirihorachai, Veerin R., Yan, Wei, Kemp, Samantha B., Kerk, Samuel A., Bollampally, Murali, Yang, Sion, Scales, Michael K., Avritt, Faith R., Lima, Fatima, Lyssiotis, Costas A., Rao, Arvind, Crawford, Howard C., Bednar, Filip, Frankel, Timothy L., Allen, Benjamin L., Zhang, Yaqing, Pasca di Magliano, Marina
Publicado 2022

Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context

por Kerk, Samuel A, Lin, Lin, Myers, Amy L, Sutton, Damien J, Andren, Anthony, Sajjakulnukit, Peter, Zhang, Li, Zhang, Yaqing, Jiménez, Jennifer A, Nelson, Barbara S, Chen, Brandon, Robinson, Anthony, Thurston, Galloway, Kemp, Samantha B, Steele, Nina G, Hoffman, Megan T, Wen, Hui-Ju, Long, Daniel, Ackenhusen, Sarah E, Ramos, Johanna, Gao, Xiaohua, Nwosu, Zeribe C, Galban, Stefanie, Halbrook, Christopher J, Lombard, David B, Piwnica-Worms, David R, Ying, Haoqiang, Pasca di Magliano, Marina, Crawford, Howard C, Shah, Yatrik M, Lyssiotis, Costas A
Publicado 2022

Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

por Halbrook, Christopher J., Thurston, Galloway, Boyer, Seth, Anaraki, Cecily, Jiménez, Jennifer A., McCarthy, Amy, Steele, Nina G., Kerk, Samuel A., Hong, Hanna S., Lin, Lin, Law, Fiona V., Felton, Catherine, Scipioni, Lorenzo, Sajjakulnukit, Peter, Andren, Anthony, Beutel, Alica K., Singh, Rima, Nelson, Barbara S., Van Den Bergh, Fran, Krall, Abigail S., Mullen, Peter J., Zhang, Li, Batra, Sandeep, Morton, Jennifer P., Stanger, Ben Z., Christofk, Heather R., Digman, Michelle A., Beard, Daniel A., Viale, Andrea, Zhang, Ji, Crawford, Howard C., Pasca di Magliano, Marina, Jorgensen, Claus, Lyssiotis, Costas A.
Publicado 2022

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis

por Kremer, Daniel M., Nelson, Barbara S., Lin, Lin, Yarosz, Emily L., Halbrook, Christopher J., Kerk, Samuel A., Sajjakulnukit, Peter, Myers, Amy, Thurston, Galloway, Hou, Sean W., Carpenter, Eileen S., Andren, Anthony C., Nwosu, Zeribe C., Cusmano, Nicholas, Wisner, Stephanie, Mbah, Nneka E., Shan, Mengrou, Das, Nupur K., Magnuson, Brian, Little, Andrew C., Savani, Milan R., Ramos, Johanna, Gao, Tina, Sastra, Stephen A., Palermo, Carmine F., Badgley, Michael A., Zhang, Li, Asara, John M., McBrayer, Samuel K., di Magliano, Marina Pasca, Crawford, Howard C., Shah, Yatrik M., Olive, Kenneth P., Lyssiotis, Costas A.
Publicado 2021