Transcriptome Analysis in a Primary Human Muscle Cell Differentiation Model for Myotonic Dystrophy Type 1

por Todorow, Vanessa, Hintze, Stefan, Kerr, Alastair R. W., Hehr, Andreas, Schoser, Benedikt, Meinke, Peter
Publicado 2021

In vitro BioID: mapping the CENP-A microenvironment with high temporal and spatial resolution

por Remnant, Lucy, Booth, Daniel G., Vargiu, Giulia, Spanos, Christos, Kerr, Alastair R. W., Earnshaw, William C.
Publicado 2019

Analysis of RNA-Seq datasets reveals enrichment of tissue-specific splice variants for nuclear envelope proteins

por Capitanchik, Charlotte, Dixon, Charles R., Swanson, Selene K., Florens, Laurence, Kerr, Alastair R. W., Schirmer, Eric C.
Publicado 2018

Tissue-specific NETs alter genome organization and regulation even in a heterologous system

por de las Heras, Jose I., Zuleger, Nikolaj, Batrakou, Dzmitry G., Czapiewski, Rafal, Kerr, Alastair R. W., Schirmer, Eric C.
Publicado 2017

Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments

por Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Sivakumar, Aishwarya, Kerr, Alastair R.W., Schirmer, Eric C.
Publicado 2017

System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics

por Zuleger, Nikolaj, Kelly, David A., Richardson, A. Christine, Kerr, Alastair R. W., Goldberg, Martin W., Goryachev, Andrew B., Schirmer, Eric C.
Publicado 2011

Orphan CpG Islands Identify Numerous Conserved Promoters in the Mammalian Genome

por Illingworth, Robert S., Gruenewald-Schneider, Ulrike, Webb, Shaun, Kerr, Alastair R. W., James, Keith D., Turner, Daniel J., Smith, Colin, Harrison, David J., Andrews, Robert, Bird, Adrian P.
Publicado 2010

Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome

por Illingworth, Robert S., Gruenewald-Schneider, Ulrike, De Sousa, Dina, Webb, Shaun, Merusi, Cara, Kerr, Alastair R. W., James, Keith D., Smith, Colin, Walker, Robert, Andrews, Robert, Bird, Adrian P.
Publicado 2015

Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis

por Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Lê Thành, Phú, Booth, Daniel G., Kelly, David A., Webb, Shaun, Kerr, Alastair R.W., Schirmer, Eric C.
Publicado 2016

Several Novel Nuclear Envelope Transmembrane Proteins Identified in Skeletal Muscle Have Cytoskeletal Associations

por Wilkie, Gavin S., Korfali, Nadia, Swanson, Selene K., Malik, Poonam, Srsen, Vlastimil, Batrakou, Dzmitry G., de las Heras, Jose, Zuleger, Nikolaj, Kerr, Alastair R. W., Florens, Laurence, Schirmer, Eric C.
Publicado 2011

The nuclear envelope proteome differs notably between tissues

por Korfali, Nadia, Wilkie, Gavin S., Swanson, Selene K., Srsen, Vlastimil, de las Heras, Jose, Batrakou, Dzmitry G., Malik, Poonam, Zuleger, Nikolaj, Kerr, Alastair R.W., Florens, Laurence, Schirmer, Eric C.
Publicado 2012

A multistage sequencing strategy pinpoints novel candidate alleles for Emery-Dreifuss muscular dystrophy and supports gene misregulation as its pathomechanism

por Meinke, Peter, Kerr, Alastair R.W., Czapiewski, Rafal, de las Heras, Jose I., Dixon, Charles R., Harris, Elizabeth, Kölbel, Heike, Muntoni, Francesco, Schara, Ulrike, Straub, Volker, Schoser, Benedikt, Wehnert, Manfred, Schirmer, Eric C.
Publicado 2019

The Leukocyte Nuclear Envelope Proteome Varies with Cell Activation and Contains Novel Transmembrane Proteins That Affect Genome Architecture

por Korfali, Nadia, Wilkie, Gavin S., Swanson, Selene K., Srsen, Vlastimil, Batrakou, Dzmitry G., Fairley, Elizabeth A. L., Malik, Poonam, Zuleger, Nikolaj, Goncharevich, Alexander, de las Heras, Jose, Kelly, David A., Kerr, Alastair R. W., Florens, Laurence, Schirmer, Eric C.
Publicado 2010

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, ex...

por Bikkul, Mehmet U., Faragher, Richard G. A., Worthington, Gemma, Meinke, Peter, Kerr, Alastair R. W., Sammy, Aakila, Riyahi, Kumars, Horton, Daniel, Schirmer, Eric C., Hubank, Michael, Kill, Ian R., Anderson, Rhona M., Slijepcevic, Predrag, Makarov, Evgeny, Bridger, Joanna M.
Publicado 2019