Small-molecule targeted therapies induce dependence on DNA double-strand break repair in residual tumor cells

por Ali, Moiez, Lu, Min, Ang, Hazel Xiaohui, Soderquist, Ryan S., Eyler, Christine E., Hutchinson, Haley M., Glass, Carolyn, Bassil, Christopher F., Lopez, Omar M., Kerr, D. Lucas, Falcon, Christina J., Yu, Helena A., Hata, Aaron N., Blakely, Collin M., McCoach, Caroline E., Bivona, Trever G., Wood, Kris C.
Publicado 2022

Deficiency of the splicing factor RBM10 limits EGFR inhibitor response in EGFR-mutant lung cancer

por Nanjo, Shigeki, Wu, Wei, Karachaliou, Niki, Blakely, Collin M., Suzuki, Junji, Chou, Yu-Ting, Ali, Siraj M., Kerr, D. Lucas, Olivas, Victor R., Shue, Jonathan, Rotow, Julia, Mayekar, Manasi K., Haderk, Franziska, Chatterjee, Nilanjana, Urisman, Anatoly, Yeo, Jia Chi, Skanderup, Anders J., Tan, Aaron C., Tam, Wai Leong, Arrieta, Oscar, Hosomichi, Kazuyoshi, Nishiyama, Akihiro, Yano, Seiji, Kirichok, Yuriy, Tan, Daniel S.W., Rosell, Rafael, Okimoto, Ross A, Bivona, Trever G.
Publicado 2022

AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

por Noronha, Ashish, Belugali Nataraj, Nishanth, Lee, Joo Sang, Zhitomirsky, Benny, Oren, Yaara, Oster, Sara, Lindzen, Moshit, Mukherjee, Saptaparna, Will, Rainer, Ghosh, Soma, Simoni-Nieves, Arturo, Verma, Aakanksha, Chatterjee, Rishita, Borgoni, Simone, Robinson, Welles, Sinha, Sanju, Brandis, Alexander, Kerr, D. Lucas, Wu, Wei, Sekar, Arunachalam, Giri, Suvendu, Chung, Youngmin, Drago-Garcia, Diana, Danysh, Brian P., Lauriola, Mattia, Fiorentino, Michelangelo, Ardizzoni, Andrea, Oren, Moshe, Blakely, Collin M., Ezike, Jideofor, Wiemann, Stefan, Parida, Laxmi, Bivona, Trever G., Aqeilan, Rami I., Brugge, Joan S., Regev, Aviv, Getz, Gad, Ruppin, Eytan, Yarden, Yosef
Publicado 2022

Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing

por Maynard, Ashley, McCoach, Caroline E., Rotow, Julia K., Harris, Lincoln, Haderk, Franziska, Kerr, D. Lucas, Yu, Elizabeth A., Schenk, Erin L., Tan, Weilun, Zee, Alexander, Tan, Michelle, Gui, Philippe, Lea, Tasha, Wu, Wei, Urisman, Anatoly, Jones, Kirk, Sit, Rene, Kolli, Pallav K., Seeley, Eric, Gesthalter, Yaron, Le, Daniel D., Yamauchi, Kevin A., Naeger, David M., Bandyopadhyay, Sourav, Shah, Khyati, Cech, Lauren, Thomas, Nicholas J., Gupta, Anshal, Gonzalez, Mayra, Do, Hien, Tan, Lisa, Bacaltos, Bianca, Gomez-Sjoberg, Rafael, Gubens, Matthew, Jahan, Thierry, Kratz, Johannes R., Jablons, David, Neff, Norma, Doebele, Robert C., Weissman, Jonathan, Blakely, Collin M., Darmanis, Spyros, Bivona, Trever G.
Publicado 2020