ABC transporter research: going strong 40 years on

por Theodoulou, Frederica L., Kerr, Ian D.
Publicado 2015

Analysis of the Sam50 translocase of Excavate organisms supports evolution of divergent organelles from a common endosymbiotic event

por Kay, Christopher J., Lawler, Karen, Kerr, Ian D.
Publicado 2013

The multidrug transporter ABCG2: still more questions than answers

por Horsey, Aaron J., Cox, Megan H., Sarwat, Sunehera, Kerr, Ian D.
Publicado 2016

Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets

por Cox, Megan H., Kapoor, Parth, Briggs, Deborah A., Kerr, Ian D.
Publicado 2018

Disruption of the Unique ABCG-Family NBD:NBD Interface Impacts Both Drug Transport and ATP Hydrolysis

por Kapoor, Parth, Briggs, Deborah A., Cox, Megan H., Kerr, Ian D.
Publicado 2020

Extracellular Vesicles Potentiate Medulloblastoma Metastasis in an EMMPRIN and MMP-2 Dependent Manner

por Jackson, Hannah K., Mitoko, Christine, Linke, Franziska, Macarthur, Donald, Kerr, Ian D., Coyle, Beth
Publicado 2023

Analysis of Sequence Divergence in Mammalian ABCGs Predicts a Structural Network of Residues That Underlies Functional Divergence

por Mitchell-White, James I., Stockner, Thomas, Holliday, Nicholas, Briddon, Stephen J., Kerr, Ian D.
Publicado 2021

Application of fluorescence correlation spectroscopy to study substrate binding in styrene maleic acid lipid copolymer encapsulated ABCG2

por Horsey, Aaron J., Briggs, Deborah A., Holliday, Nicholas D., Briddon, Stephen J., Kerr, Ian D.
Publicado 2020

The ATP-Binding Cassette Proteins of the Deep-Branching Protozoan Parasite Trichomonas vaginalis

por Kay, Christopher, Woodward, Katharine D., Lawler, Karen, Self, Tim J., Dyall, Sabrina D., Kerr, Ian D.
Publicado 2012

Dimerization of ABCG2 Analysed by Bimolecular Fluorescence Complementation

por Haider, Ameena J., Briggs, Deborah, Self, Tim J., Chilvers, Hannah L., Holliday, Nicholas D., Kerr, Ian D.
Publicado 2011

BLBP Is Both a Marker for Poor Prognosis and a Potential Therapeutic Target in Paediatric Ependymoma

por Sabnis, Durgagauri H., Liu, Jo-Fen, Simmonds, Lucy, Blackburn, Sophie, Grundy, Richard G., Kerr, Ian D., Coyle, Beth
Publicado 2021

Picky ABCG5/G8 and promiscuous ABCG2 ‐ a tale of fatty diets and drug toxicity

por Khunweeraphong, Narakorn, Mitchell‐White, James, Szöllősi, Dániel, Hussein, Toka, Kuchler, Karl, Kerr, Ian D., Stockner, Thomas, Lee, Jyh‐Yeuan
Publicado 2020

3D hydrogels reveal medulloblastoma subgroup differences and identify extracellular matrix subtypes that predict patient outcome

por Linke, Franziska, Aldighieri, Macha, Lourdusamy, Anbarasu, Grabowska, Anna M, Stolnik, Snow, Kerr, Ian D, Merry, Catherine LR, Coyle, Beth
Publicado 2020

Identification of residues in ABCG2 affecting protein trafficking and drug transport, using co-evolutionary analysis of ABCG sequences

por Haider, Ameena J., Cox, Megan H., Jones, Natalie, Goode, Alice J., Bridge, Katherine S., Wong, Kelvin, Briggs, Deborah, Kerr, Ian D.
Publicado 2015

Drug Resistance in Medulloblastoma Is Driven by YB-1, ABCB1 and a Seven-Gene Drug Signature

por Taylor, Louisa, Wade, Philippa K., Johnson, James E. C., Aldighieri, Macha, Morlando, Sonia, Di Leva, Gianpiero, Kerr, Ian D., Coyle, Beth
Publicado 2023

Overcoming multiple drug resistance mechanisms in medulloblastoma

por Othman, Ramadhan T, Kimishi, Ioanna, Bradshaw, Tracey D, Storer, Lisa CD, Korshunov, Andrey, Pfister, Stefan M, Grundy, Richard G, Kerr, Ian D, Coyle, Beth
Publicado 2014

A role for ABCB1 in prognosis, invasion and drug resistance in ependymoma

por Sabnis, Durgagauri H., Storer, Lisa C. D., Liu, Jo-Fen, Jackson, Hannah K., Kilday, J. P., Grundy, Richard G., Kerr, Ian D., Coyle, Beth
Publicado 2019

ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma

por Nasir, Aishah, Cardall, Alice, Othman, Ramadhan T, Nicolaou, Niovi, Lourdusamy, Anbarasu, Linke, Franziska, Onion, David, Ryzhova, Marina, Cameron, Hanna, Valente, Cara, Ritchie, Alison, Korshunov, Andrey, Pfister, Stefan M, Grabowska, Anna M, Kerr, Ian D, Coyle, Beth
Publicado 2021

Corrigendum to: ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma

por Nasir, Aishah, Cardall, Alice, Othman, Ramadhan T, Nicolaou, Niovi, Lourdusamy, Anbarasu, Linke, Franziska, Onion, David, Ryzhova, Marina, Cameron, Hanna, Valente, Cara, Ritchie, Alison, Korshunov, Andrey, Pfister, Stefan M, Grabowska, Anna M, Kerr, Ian D, Coyle, Beth
Publicado 2021

Pediatric brain tumor cancer stem cells: cell cycle dynamics, DNA repair, and etoposide extrusion

por Hussein, Deema, Punjaruk, Wiyada, Storer, Lisa C.D., Shaw, Lucy, Ottoman, Ramadan, Peet, Andrew, Miller, Suzanne, Bandopadhyay, Gagori, Heath, Rachel, Kumari, Rajendra, Bowman, Karen J., Braker, Paul, Rahman, Ruman, Jones, George D.D., Watson, Susan, Lowe, James, Kerr, Ian D., Grundy, Richard G., Coyle, Beth
Publicado 2011