Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic

por Rossmueller, Gregor, Mirkina, Irina, Maurer, Barbara, Hoeld, Verena, Mayer, Julia, Thiele, Michael, Kerschbaumer, Randolf J., Schinagl, Alexander
Publicado 2023

Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer

por Schinagl, Alexander, Thiele, Michael, Douillard, Patrice, Völkel, Dirk, Kenner, Lukas, Kazemi, Zahra, Freissmuth, Michael, Scheiflinger, Friedrich, Kerschbaumer, Randolf J.
Publicado 2016

Fully human anti-macrophage migration inhibitory factor antibodies as potential therapeutics for sepsis and septic shock

por Kerschbaumer, Randolf, Rieger, Manfred, Antoine, Gerhard, Völkel, Dirk, Le Roy, Didier, Roger, Thierry, Savidis-Dacho, Helga, Calandra, Thierry, Scheiflinger, Fritz
Publicado 2008

Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics

por Douillard, Patrice, Freissmuth, Michael, Antoine, Gerhard, Thiele, Michael, Fleischanderl, Daniel, Matthiessen, Peter, Voelkel, Dirk, Kerschbaumer, Randolf J., Scheiflinger, Friedrich, Sabarth, Nicolas
Publicado 2019