Comparing Randomized Controlled Trials and Real-World Studies in Chronic Obstructive Pulmonary Disease Pharmacotherapy

por Tashkin, Donald P, Amin, Alpesh N, Kerwin, Edward M
Publicado 2020

Clinically Important Deterioration Among Patients with Chronic Obstructive Pulmonary Disease (COPD) Treated with Nebulized Glycopyrrolate: A Post Hoc Analysis of Pooled Data from T...

por Kerwin, Edward M, Murray, Lindsey, Niu, Xiaoli, Dembek, Carole
Publicado 2020

Efficacy and Safety of Umeclidinium Added to Fluticasone Propionate/Salmeterol in Patients with COPD: Results of Two Randomized, Double-Blind Studies

por Siler, Thomas M., Kerwin, Edward, Singletary, Karen, Brooks, Jean, Church, Alison
Publicado 2016

Effect of background long-acting beta(2)-agonist therapy on the efficacy and safety of a novel, nebulized glycopyrrolate in subjects with moderate-to-very-severe COPD

por Kerwin, Edward M, Tosiello, Robert, Price, Barry, Sanjar, Shahin, Goodin, Thomas
Publicado 2018

Pharmacokinetic Study of Epinephrine Hydrofluoroalkane (Primatene MIST) Metered-Dose Inhaler

por Kerwin, Edward M., Marrs, Tony, Luo, Mary Z., Zhang, Jack Y.
Publicado 2020

A Dose-Ranging Study of the Novel Inhaled Dual PDE 3 and 4 Inhibitor Ensifentrine in Patients with COPD Receiving Maintenance Tiotropium Therapy

por Ferguson, Gary T, Kerwin, Edward M, Rheault, Tara, Bengtsson, Thomas, Rickard, Kathleen
Publicado 2021

A phase IIb randomized, chronic-dosing, incomplete block, cross-over study of glycopyrronium, delivered via metered dose inhaler, compared with a placebo and an active control in p...

por Kerwin, Edward M., Spangenthal, Selwyn, Kollar, Christine, St Rose, Earl, Reisner, Colin
Publicado 2018

In Vitro Characterization of the eFlow Closed System Nebulizer with Glycopyrrolate Inhalation Solution

por Pham, Stephen, Ferguson, Gary T., Kerwin, Edward, Goodin, Thomas, Wheeler, Alistair, Bauer, Andrea
Publicado 2018

Efficacy and safety of four doses of glycopyrrolate/formoterol fumarate delivered via a metered dose inhaler compared with the monocomponents in patients with moderate-to-severe CO...

por Reisner, Colin, Pearle, James, Kerwin, Edward M, Rose, Earl St, Darken, Patrick
Publicado 2018

Weighing the evidence for pharmacological treatment interventions in mild COPD; a narrative perspective

por Singh, Dave, D’Urzo, Anthony D., Donohue, James F., Kerwin, Edward M.
Publicado 2019

Bone and ocular safety of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a 52-week randomized study

por Kerwin, Edward M., Ferguson, Gary T., Mo, Mindy, DeAngelis, Kiernan, Dorinsky, Paul
Publicado 2019

Real-world health care utilization in asthma patients using albuterol sulfate inhalation aerosol (ProAir(®) HFA) with and without integrated dose counters

por Kerwin, Edward M, Ferro, Thomas J, Ariely, Rinat, Irwin, Debra E, Parikh, Ruchir
Publicado 2017

A 28-day, randomized, double-blind, placebo-controlled, parallel group study of nebulized revefenacin in patients with chronic obstructive pulmonary disease

por Pudi, Krishna K., Barnes, Chris N., Moran, Edmund J., Haumann, Brett, Kerwin, Edward
Publicado 2017

Efficacy, safety, and pharmacokinetics of budesonide/formoterol fumarate delivered via metered dose inhaler using innovative co-suspension delivery technology in patients with mode...

por Kerwin, Edward M, Siler, Thomas M, Arora, Samir, Darken, Patrick, Rose, Earl, Reisner, Colin
Publicado 2018

Efficacy of revefenacin, a long-acting muscarinic antagonist for nebulized therapy, in patients with markers of more severe COPD: a post hoc subgroup analysis

por Donohue, James F., Kerwin, Edward, Barnes, Chris N., Moran, Edmund J., Haumann, Brett, Crater, Glenn D.
Publicado 2020

Observational Real-World Study to Assess Clinical Characteristics and Device Satisfaction in Patients with COPD Treated with Glycopyrrolate/eFlow(®) CS

por Stephenson, Judith J, Dembek, Carole, Caldwell-Tarr, Amanda, Conto, Rebecca M, Paullin, Mark, Kerwin, Edward M
Publicado 2020

Dose-Ranging and Cumulative Dose Studies of Albuterol Sulfate MDI in Co-Suspension Delivery™ Technology (AS MDI; PT007) in Patients with Asthma: the ASPEN and ANTORA Trials

por Cappelletti, Christy, Maes, Andrea, Rossman, Kimberly, Gillen, Michael, LaForce, Craig, Kerwin, Edward M., Reisner, Colin
Publicado 2021

Effects of mometasone furoate/formoterol fumarate fixed-dose combination formulation on chronic obstructive pulmonary disease (COPD): results from a 52-week Phase III trial in subj...

por Doherty, Dennis E, Tashkin, Donald P, Kerwin, Edward, Knorr, Barbara A, Shekar, Tulin, Banerjee, Sibabrata, Staudinger, Heribert
Publicado 2012

Efficacy and safety of NVA237 versus placebo and tiotropium in patients with COPD: the GLOW2 study

por Kerwin, Edward, Hébert, Jacques, Gallagher, Nicola, Martin, Carmen, Overend, Tim, Alagappan, Vijay K.T., Lu, Yimeng, Banerji, Donald
Publicado 2012

Clinical Bioequivalence of Wixela Inhub and Advair Diskus in Adults With Asthma

por Ng, Dik, Kerwin, Edward M., White, Martha V., Miller, S. David, Haughie, Scott, Ward, Jonathan K., Allan, Richard
Publicado 2020