MEDB-73. Lipid metabolism as a therapeutic vulnerability in BET inhibitor-resistant medulloblastoma

por Lupien, Leslie, Boynton, Adam, Chacon, Madison, Kumbhani, Rushil, Gionet, Gabrielle, Goodale, Amy, Root, David, Keshishian, Hasmik, Robinson, Margaret, Carr, Steven, Bandopadhayay, Pratiti
Publicado 2022

MEDB-85. Transcriptional complexes as resistance drivers to BET inhibition

por Boynton, Adam, Lupien, Leslie, Kumbhani, Rushil, Gionet, Gabrielle, Chacon, Madison, Goodale, Amy, Root, David, Keshishian, Hasmik, Robinson, Margaret, Carr, Steven, Bandopadhayay, Pratiti
Publicado 2022

A bidirectional switch in the Shank3 phosphorylation state biases synapses toward up- or downscaling

por Wu, Chi-Hong, Tatavarty, Vedakumar, Jean Beltran, Pierre M, Guerrero, Andrea A, Keshishian, Hasmik, Krug, Karsten, MacMullan, Melanie A, Li, Li, Carr, Steven A, Cottrell, Jeffrey R, Turrigiano, Gina G
Publicado 2022

TAILS Identifies Candidate Substrates and Biomarkers of ADAMTS7, a Therapeutic Protease Target in Coronary Artery Disease

por MacDonald, Bryan T., Keshishian, Hasmik, Mundorff, Charles C., Arduini, Alessandro, Lai, Daniel, Bendinelli, Kayla, Popp, Nicholas R., Bhandary, Bidur, Clauser, Karl R., Specht, Harrison, Elowe, Nadine H., Laprise, Dylan, Xing, Yi, Kaushik, Virendar K., Carr, Steven A., Ellinor, Patrick T.
Publicado 2022

Optimized Liquid and Gas Phase Fractionation Increases HLA-Peptidome Coverage for Primary Cell and Tissue Samples

por Klaeger, Susan, Apffel, Annie, Clauser, Karl R., Sarkizova, Siranush, Oliveira, Giacomo, Rachimi, Suzanna, Le, Phuong M., Tarren, Anna, Chea, Vipheaviny, Abelin, Jennifer G., Braun, David A., Ott, Patrick A., Keshishian, Hasmik, Hacohen, Nir, Keskin, Derin B., Wu, Catherine J., Carr, Steven A.
Publicado 2021

The SARS-CoV-2 RNA–protein interactome in infected human cells

por Schmidt, Nora, Lareau, Caleb A., Keshishian, Hasmik, Ganskih, Sabina, Schneider, Cornelius, Hennig, Thomas, Melanson, Randy, Werner, Simone, Wei, Yuanjie, Zimmer, Matthias, Ade, Jens, Kirschner, Luisa, Zielinski, Sebastian, Dölken, Lars, Lander, Eric S., Caliskan, Neva, Fischer, Utz, Vogel, Jörg, Carr, Steven A., Bodem, Jochen, Munschauer, Mathias
Publicado 2020

A large peptidome dataset improves HLA class I epitope prediction across most of the human population

por Sarkizova, Siranush, Klaeger, Susan, Le, Phuong M., Li, Letitia W., Oliveira, Giacomo, Keshishian, Hasmik, Hartigan, Christina R., Zhang, Wandi, Braun, David A., Ligon, Keith L., Bachireddy, Pavan, Zervantonakis, Ioannis K., Rosenbluth, Jennifer M., Ouspenskaia, Tamara, Law, Travis, Justesen, Sune, Stevens, Jonathan, Lane, William J., Eisenhaure, Thomas, Zhang, Guang Lan, Clauser, Karl R., Hacohen, Nir, Carr, Steven A., Wu, Catherine J., Keskin, Derin B.
Publicado 2019

DIPG-53. CHARACTERIZING THE ROLE OF PPM1D MUTATIONS IN THE PATHOGENESIS OF DIFFUSE INTRINSIC PONTINE GLIOMAS (DIPGS)

por Khadka, Prasidda, Reitman, Zachary, Lu, Sophie, Buchan, Graham, Hartley, Rachel, Bear, Heather, Georgis, Yoahnna, Jarmale, Spandana, Schoolcraft, Kathleen, Miller, Peter, Gonzalez, Elizabeth, Gionet, Gabrielle, Qian, Kenin, Melanson, Randy, Keshishian, Hasmik, Carvalho, Diana, Condurat, Alexandra, Goodale, Amy, Abid, Tanaz, Piccioni, Federica, Chi, Susan, Carr, Steven, Haas-Kogan, Daphne, Ebert, Benjamin, Kieran, Mark, Jones, Chris, Ligon, Keith, Beroukhim, Rameen, Phoenix, Timothy, Bandopadhayay, Pratiti
Publicado 2020

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9

por Schmidt, Nora, Ganskih, Sabina, Wei, Yuanjie, Gabel, Alexander, Zielinski, Sebastian, Keshishian, Hasmik, Lareau, Caleb A., Zimmermann, Liv, Makroczyova, Jana, Pearce, Cadence, Krey, Karsten, Hennig, Thomas, Stegmaier, Sebastian, Moyon, Lambert, Horlacher, Marc, Werner, Simone, Aydin, Jens, Olguin-Nava, Marco, Potabattula, Ramya, Kibe, Anuja, Dölken, Lars, Smyth, Redmond P., Caliskan, Neva, Marsico, Annalisa, Krempl, Christine, Bodem, Jochen, Pichlmair, Andreas, Carr, Steven A., Chlanda, Petr, Erhard, Florian, Munschauer, Mathias
Publicado 2023

A highly multiplexed quantitative phosphosite assay for biology and preclinical studies

por Keshishian, Hasmik, McDonald, E Robert, Mundt, Filip, Melanson, Randy, Krug, Karsten, Porter, Dale A, Wallace, Luke, Forestier, Dominique, Rabasha, Bokang, Marlow, Sara E, Jane‐Valbuena, Judit, Todres, Ellen, Specht, Harrison, Robinson, Margaret Lea, Jean Beltran, Pierre M, Babur, Ozgun, Olive, Meagan E, Golji, Javad, Kuhn, Eric, Burgess, Michael, MacMullan, Melanie A, Rejtar, Tomas, Wang, Karen, Mani, DR, Satpathy, Shankha, Gillette, Michael A, Sellers, William R, Carr, Steven A
Publicado 2021

Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach

por Carr, Steven A., Abbatiello, Susan E., Ackermann, Bradley L., Borchers, Christoph, Domon, Bruno, Deutsch, Eric W., Grant, Russell P., Hoofnagle, Andrew N., Hüttenhain, Ruth, Koomen, John M., Liebler, Daniel C., Liu, Tao, MacLean, Brendan, Mani, DR, Mansfield, Elizabeth, Neubert, Hendrik, Paulovich, Amanda G., Reiter, Lukas, Vitek, Olga, Aebersold, Ruedi, Anderson, Leigh, Bethem, Robert, Blonder, Josip, Boja, Emily, Botelho, Julianne, Boyne, Michael, Bradshaw, Ralph A., Burlingame, Alma L., Chan, Daniel, Keshishian, Hasmik, Kuhn, Eric, Kinsinger, Christopher, Lee, Jerry S.H., Lee, Sang-Won, Moritz, Robert, Oses-Prieto, Juan, Rifai, Nader, Ritchie, James, Rodriguez, Henry, Srinivas, Pothur R., Townsend, R. Reid, Van Eyk, Jennifer, Whiteley, Gordon, Wiita, Arun, Weintraub, Susan
Publicado 2014

PPM1D mutations are oncogenic drivers of de novo diffuse midline glioma formation

por Khadka, Prasidda, Reitman, Zachary J., Lu, Sophie, Buchan, Graham, Gionet, Gabrielle, Dubois, Frank, Carvalho, Diana M., Shih, Juliann, Zhang, Shu, Greenwald, Noah F., Zack, Travis, Shapira, Ofer, Pelton, Kristine, Hartley, Rachel, Bear, Heather, Georgis, Yohanna, Jarmale, Spandana, Melanson, Randy, Bonanno, Kevin, Schoolcraft, Kathleen, Miller, Peter G., Condurat, Alexandra L., Gonzalez, Elizabeth M., Qian, Kenin, Morin, Eric, Langhnoja, Jaldeep, Lupien, Leslie E., Rendo, Veronica, Digiacomo, Jeromy, Wang, Dayle, Zhou, Kevin, Kumbhani, Rushil, Guerra Garcia, Maria E., Sinai, Claire E., Becker, Sarah, Schneider, Rachel, Vogelzang, Jayne, Krug, Karsten, Goodale, Amy, Abid, Tanaz, Kalani, Zohra, Piccioni, Federica, Beroukhim, Rameen, Persky, Nicole S., Root, David E., Carcaboso, Angel M., Ebert, Benjamin L., Fuller, Christine, Babur, Ozgun, Kieran, Mark W., Jones, Chris, Keshishian, Hasmik, Ligon, Keith L., Carr, Steven A., Phoenix, Timothy N., Bandopadhayay, Pratiti
Publicado 2022