CMGC Kinases in Health and Cancer

por Chowdhury, Iftekhar, Dashi, Giovanna, Keskitalo, Salla
Publicado 2023

Altered glycosylation of several metastasis-associated glycoproteins with terminal GalNAc defines the highly invasive cancer cell phenotype

por Khosrowabadi, Elham, Wenta, Tomasz, Keskitalo, Salla, Manninen, Aki, Kellokumpu, Sakari
Publicado 2022

Physical and functional interactome atlas of human receptor tyrosine kinases

por Salokas, Kari, Liu, Xiaonan, Öhman, Tiina, Chowdhury, Iftekhar, Gawriyski, Lisa, Keskitalo, Salla, Varjosalo, Markku
Publicado 2022

The Impact of ETV6-NTRK3 Oncogenic Gene Fusions on Molecular and Signaling Pathway Alterations

por Kinnunen, Matias, Liu, Xiaonan, Niemelä, Elina, Öhman, Tiina, Gawriyski, Lisa, Salokas, Kari, Keskitalo, Salla, Varjosalo, Markku
Publicado 2023

IRF2BP2 Mutation Is Associated with Increased STAT1 and STAT5 Activation in Two Family Members with Inflammatory Conditions and Lymphopenia

por Palmroth, Maaria, Viskari, Hanna, Seppänen, Mikko R. J., Keskitalo, Salla, Virtanen, Anniina, Varjosalo, Markku, Silvennoinen, Olli, Isomäki, Pia
Publicado 2021

Reciprocal modulation of Aβ42 aggregation by copper and homocysteine

por Keskitalo, Salla, Farkas, Melinda, Hanenberg, Michael, Szodorai, Anita, Kulic, Luka, Semmler, Alexander, Weller, Michael, Nitsch, Roger M., Linnebank, Michael
Publicado 2014

Heterozygous premature termination in zinc-finger domain of Krüppel-like factor 2 gene associates with dysregulated immunity

por Pernaa, Nora, Keskitalo, Salla, Chowdhury, Iftekhar, Nissinen, Antti, Glumoff, Virpi, Keski-Filppula, Riikka, Junttila, Juhani, Eklund, Kari K., Santaniemi, Wenny, Siitonen, Sanna, Seppänen, Mikko RJ., Vähäsalo, Paula, Varjosalo, Markku, Åström, Pirjo, Hautala, Timo
Publicado 2022

Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease

por Keskitalo, Salla, Haapaniemi, Emma M., Glumoff, Virpi, Liu, Xiaonan, Lehtinen, Ville, Fogarty, Christopher, Rajala, Hanna, Chiang, Samuel C., Mustjoki, Satu, Kovanen, Panu, Lohi, Jouko, Bryceson, Yenan T., Seppänen, Mikko, Kere, Juha, Heiskanen, Kaarina, Varjosalo, Markku
Publicado 2019

SARS‐CoV‐2–host proteome interactions for antiviral drug discovery

por Liu, Xiaonan, Huuskonen, Sini, Laitinen, Tuomo, Redchuk, Taras, Bogacheva, Mariia, Salokas, Kari, Pöhner, Ina, Öhman, Tiina, Tonduru, Arun Kumar, Hassinen, Antti, Gawriyski, Lisa, Keskitalo, Salla, Vartiainen, Maria K, Pietiäinen, Vilja, Poso, Antti, Varjosalo, Markku
Publicado 2021

Characterization of Expanded Gamma Delta T Cells from Atypical X-SCID Patient Reveals Preserved Function and IL2RG-Mediated Signaling

por Tuovinen, Elina A., Pöysti, Sakari, Hamdan, Firas, Le, Kim My, Keskitalo, Salla, Turunen, Tanja, Minier, Léa, Mamia, Nanni, Heiskanen, Kaarina, Varjosalo, Markku, Cerullo, Vincenzo, Kere, Juha, Seppänen, Mikko R. J., Hänninen, Arno, Grönholm, Juha
Publicado 2022

Haploinsufficiency of A20 impairs protein–protein interactome and leads into caspase-8-dependent enhancement of NLRP3 inflammasome activation

por Rajamäki, Kristiina, Keskitalo, Salla, Seppänen, Mikko, Kuismin, Outi, Vähäsalo, Paula, Trotta, Luca, Väänänen, Antti, Glumoff, Virpi, Keskitalo, Paula, Kaarteenaho, Riitta, Jartti, Airi, Hautala, Nina, Jackson, Päivi, Nordström, Dan C, Saarela, Janna, Hautala, Timo, Eklund, Kari K, Varjosalo, Markku
Publicado 2018

Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

por Keskitalo, Salla, Haapaniemi, Emma, Einarsdottir, Elisabet, Rajamäki, Kristiina, Heikkilä, Hannele, Ilander, Mette, Pöyhönen, Minna, Morgunova, Ekaterina, Hokynar, Kati, Lagström, Sonja, Kivirikko, Sirpa, Mustjoki, Satu, Eklund, Kari, Saarela, Janna, Kere, Juha, Seppänen, Mikko R. J., Ranki, Annamari, Hannula-Jouppi, Katariina, Varjosalo, Markku
Publicado 2019

Rapid genome editing by CRISPR-Cas9-POLD3 fusion

por Reint, Ganna, Li, Zhuokun, Labun, Kornel, Keskitalo, Salla, Soppa, Inkeri, Mamia, Katariina, Tolo, Eero, Szymanska, Monika, Meza-Zepeda, Leonardo A, Lorenz, Susanne, Cieslar-Pobuda, Artur, Hu, Xian, Bordin, Diana L, Staerk, Judith, Valen, Eivind, Schmierer, Bernhard, Varjosalo, Markku, Taipale, Jussi, Haapaniemi, Emma
Publicado 2021

Common variable immunodeficiency in two kindreds with heterogeneous phenotypes caused by novel heterozygous NFKB1 mutations

por Staels, Frederik, De Keukeleere, Kerstin, Kinnunen, Matias, Keskitalo, Salla, Lorenzetti, Flaminia, Vanmeert, Michiel, Prezzemolo, Teresa, Pasciuto, Emanuela, Lescrinier, Eveline, Bossuyt, Xavier, Gerbaux, Margaux, Willemsen, Mathijs, Neumann, Julika, Van Loo, Sien, Corveleyn, Anniek, Willekens, Karen, Stalmans, Ingeborg, Meyts, Isabelle, Liston, Adrian, Humblet-Baron, Stephanie, Seppänen, Mikko, Varjosalo, Markku, Schrijvers, Rik
Publicado 2022

Reduced binding of apoE4 to complement factor H promotes amyloid‐β oligomerization and neuroinflammation

por Chernyaeva, Larisa, Ratti, Giorgio, Teirilä, Laura, Fudo, Satoshi, Rankka, Uni, Pelkonen, Anssi, Korhonen, Paula, Leskinen, Katarzyna, Keskitalo, Salla, Salokas, Kari, Gkolfinopoulou, Christina, Crompton, Katrina E, Javanainen, Matti, Happonen, Lotta, Varjosalo, Markku, Malm, Tarja, Leinonen, Ville, Chroni, Angeliki, Saavalainen, Päivi, Meri, Seppo, Kajander, Tommi, Wollman, Adam JM, Nissilä, Eija, Haapasalo, Karita
Publicado 2023