Quantification of spatial subclonal interactions enhancing the invasive phenotype of pediatric glioma

por Tari, Haider, Kessler, Ketty, Trahearn, Nick, Werner, Benjamin, Vinci, Maria, Jones, Chris, Sottoriva, Andrea
Publicado 2022

DIPG-63. LOSS OF THE H4 LYSINE METHYLTRANSFERASE KMT5B DRIVES INVASION / MIGRATION BY DEPLETING H3K27me3 AT LOCI OTHERWISE RETAINED IN H3K27M MUTANT DIPG CELLS

por Kessler, Ketty, Mackay, Alan, Molinari, Valeria, Tari, Haider, Burford, Anna, Sottoriva, Andrea, Vinci, Maria, Jones, Chris
Publicado 2020

IMG-09. Characterisation of a panel ofin vivo models of paediatric-type diffuse high-grade glioma (PDHGG) using magnetic resonance imaging

por Boult, Jessica, Carvalho, Diana, Kessler, Ketty, Vinci, Maria, Fernandez, Elisabet, Bjerke, Lynn, Fofana, Mariama, Molinari, Valeria, Carcaboso, Angel, Jones, Chris, Robinson, Simon
Publicado 2022

Zeb1 controls neuron differentiation and germinal zone exit by a mesenchymal-epithelial-like transition

por Singh, Shalini, Howell, Danielle, Trivedi, Niraj, Kessler, Ketty, Ong, Taren, Rosmaninho, Pedro, Raposo, Alexandre ASF, Robinson, Giles, Roussel, Martine F, Castro, Diogo S, Solecki, David J
Publicado 2016

HGG-42. Evolutionary selection of key oncogenic alterations in patient-derived models of paediatric diffuse high grade glioma (PDHGG) subtypesin vitro andin vivo

por Mackay, Alan, Temelso, Sara, Carvalho, Diana, Kessler, Ketty, Boult, Jessica, Izquierdo, Elisa, Pereira, Rita, Potente, Elisabet Fernandez, Burford, Anna, Molinari, Valeria, Bjerke, Lynn, Grabovska, Yura, Rogers, Rebecca, Crampsie, Shauna, Das, Molina, Robinson, Simon, Clarke, Matthew, Jones, Chris
Publicado 2022

MODL-20. A BIOBANK OF ~100 PATIENT-DERIVED MODELS REPRESENTING BIOLOGICAL HETEROGENEITY AND DISTINCT THERAPEUTIC DEPENDENCIES IN PAEDIATRIC HIGH GRADE GLIOMA AND DIPG

por Carvalho, Diana, Mackay, Alan, Temelso, Sara, Izquierdo, Elisa, Fernandez, Elisabet Potente, Rogers, Rebecca, Boult, Jessica, Salom, Janat Fazal, Simon, Natalie, Clarke, Matthew, Molinari, Valeria, Kessler, Ketty, Burford, Anna, Bjerke, Lynn, Fofana, Mariama, Hubank, Michael, Pears, Jane, Moore, Andrew, Carcaboso, Angel Montero, Marshall, Lynley, Carceller, Fernando, Robinson, Simon, Hargrave, Darren, Vinci, Maria, Jones, Chris
Publicado 2020

Pathogenic variants in THSD4, encoding the ADAMTS-like 6 protein, predispose to inherited thoracic aortic aneurysm

por Elbitar, Sandy, Renard, Marjolijn, Arnaud, Pauline, Hanna, Nadine, Jacob, Marie-Paule, Guo, Dong-Chuan, Tsutsui, Ko, Gross, Marie-Sylvie, Kessler, Ketty, Tosolini, Laurent, Dattilo, Vincenzo, Dupont, Sebastien, Jonquet, Jeremie, Langeois, Maud, Benarroch, Louise, Aubart, Melodie, Ghaleb, Youmna, Khalil, Yara Abou, Varret, Mathilde, Khoury, Petra El, Ho-Tin-Noé, Benoit, Alembik, Yves, Gaertner, Sébastien, Isidor, Bertrand, Gouya, Laurent, Milleron, Olivier, Sekiguchi, Kiyotoshi, Milewicz, Dianna, Backer, Julie De, Le Goff, Carine, Michel, Jean-Baptiste, Jondeau, Guillaume, Sakai, Lynn Y., Boileau, Catherine, Abifadel, Marianne
Publicado 2020

HGG-17. SINGLE-CELL AND SPATIAL ANALYSES DECIPHER THE UNIQUE INVASIVE GROWTH PATTERN OF GLIOMATOSIS CEREBRI

por Crampsie, Shauna, Liu, Ilon, Petrilli, Lucia Lisa, Mackay, Alan, Spinozzi, Giulio, Grabovska, Yura, Hack, Olivia A, Kessler, Ketty, Temelso, Sara, Carvalho, Diana Martins, Burford, Anna, Sejdiu, Drenusha, Molinari, Valeria, Shaw, McKenzie L, Mire, Hafsa M, Pericoli, Giulia, Cerimele, Alfredo, Barry, Clémentine, Cocito, Carolina, Debily, Marie-Anne, Kergrohen, Thomas, Ajlil, Yassine, Beccaria, Kévin, Varlet, Pascale, Tauziède-Espariat, Arnault, Mastronuzzi, Angela, Carai, Andrea, Giovannoni, Isabella, Rossi, Sabrina, Miele, Evelina, Grill, Jacques, Jacques, Thomas S, Greenfield, Jeffery P, Castel, David, Vinci, Maria, Filbin, Mariella G, Jones, Chris
Publicado 2023

Functional diversity and co-operativity between subclonal populations of paediatric glioblastoma and diffuse intrinsic pontine glioma cells

por Vinci, Mara, Burford, Anna, Molinari, Valeria, Kessler, Ketty, Popov, Sergey, Clarke, Matthew, Taylor, Kathryn R, Pemberton, Helen, Lord, Christopher J, Gutteridge, Alice, Forshew, Tim, Carvalho, Diana, Marshall, Lynley V, Qin, Elizabeth Y, Ingram, Wendy J, Moore, Andrew S, Ng, Ho-Keung, Trabelsi, Saoussen, Brahim, Dorra H’mida-Ben, Entz-Werle, Natacha, Zacharoulis, Stergios, Vaidya, Sucheta, Mandeville, Henry C, Bridges, Leslie R, Martin, Andrew J, Al-Sarraj, Safa, Chandler, Christopher, Sunol, Mariona, Mora, Jaume, de Torres, Carmen, Cruz, Ofelia, Carcaboso, Angel M, Monje, Michelle, Mackay, Alan, Jones, Chris
Publicado 2018