STAT3 mediates C6-ceramide-induced cell death in chronic lymphocytic leukemia

por Doshi, Ushma A, Shaw, Jeremy, Fox, Todd E, Claxton, David F, Loughran, Thomas P, Kester, Mark
Publicado 2017

Solid Tumor Treatment via Augmentation of Bioactive C6 Ceramide Levels with Thermally Ablative Focused Ultrasound

por Thim, E. Andrew, Fox, Todd, Deering, Tye, Vass, Luke R., Sheybani, Natasha D., Kester, Mark, Price, Richard J.
Publicado 2023

Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia

por Feng, Tzu-Yu, Melchor, Stephanie J., Zhao, Xiao-Yu, Ghumman, Haider, Kester, Mark, Fox, Todd E., Ewald, Sarah E.
Publicado 2023

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

por Linton, Samuel S., Abraham, Thomas, Liao, Jason, Clawson, Gary A., Butler, Peter J., Fox, Todd, Kester, Mark, Matters, Gail L.
Publicado 2018

Ceramide Nanoliposomes as Potential Therapeutic Reagents for Asthma

por Sakae, Harumi, Ogiso, Yuri, Matsuda, Masaya, Shimora, Hayato, Deering, Tye, Fox, Todd E., Kester, Mark, Nabe, Takeshi, Kitatani, Kazuyuki
Publicado 2023

Altered Sphingolipid Metabolism in Patients with Metastatic Pancreatic Cancer

por Jiang, Yixing, DiVittore, Nicole A., Young, Megan M, Jia, Zhiliang, Xie, Keping, Ritty, Timothy M., Kester, Mark, Fox, Todd E.
Publicado 2013

Role of SPTSSB-Regulated de Novo Sphingolipid Synthesis in Prostate Cancer Depends on Androgen Receptor Signaling

por Costa-Pinheiro, Pedro, Heher, Abigail, Raymond, Michael H., Jividen, Kasey, Shaw, Jeremy JP., Paschal, Bryce M., Walker, Susan J., Fox, Todd E., Kester, Mark
Publicado 2020

Nanoliposome C6‐Ceramide in combination with anti‐CTLA4 antibody improves anti‐tumor immunity in hepatocellular cancer

por Qi, Xiaoqiang, Wu, Feng, Kim, Sung Hoon, Kaifi, Jussuf T., Kimchi, Eric T., Snyder, Helena, Illendula, Anuradha, Fox, Todd, Kester, Mark, Staveley‐O'Carroll, Kevin F., Li, Guangfu
Publicado 2022

Minicell‐based fungal RNAi delivery for sustainable crop protection

por Islam, Md Tabibul, Davis, Zachery, Chen, Lisa, Englaender, Jacob, Zomorodi, Sepehr, Frank, Joseph, Bartlett, Kira, Somers, Elisabeth, Carballo, Sergio M., Kester, Mark, Shakeel, Ameer, Pourtaheri, Payam, Sherif, Sherif M.
Publicado 2021

A Cholecystokinin B Receptor-Specific DNA Aptamer for Targeting Pancreatic Ductal Adenocarcinoma

por Clawson, Gary A., Abraham, Thomas, Pan, Weihua, Tang, Xiaomeng, Linton, Samuel S., McGovern, Christopher O., Loc, Welley S., Smith, Jill P., Butler, Peter J., Kester, Mark, Adair, James H., Matters, Gail L.
Publicado 2017

Glucosylceramide synthase maintains influenza virus entry and infection

por Drews, Kelly, Calgi, Michael P., Harrison, William Casey, Drews, Camille M., Costa-Pinheiro, Pedro, Shaw, Jeremy Joseph Porter, Jobe, Kendra A., Han, John D., Fox, Todd E., White, Judith M., Kester, Mark
Publicado 2020

A nano-enhanced vaccine for metastatic melanoma immunotherapy

por Salotto, Katelyn E., Olson Jr, Walter C., Pollack, Karlyn E., Illendula, Anuradha, Michel, Elishama, Henriques, Sydney, Fox, Todd, Walker, Susan, Dunlap-Brown, Marya, Slingluff Jr, Craig L., Kester, Mark, Snyder, Helena W.
Publicado 2022

Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice

por Li, Guangfu, Liu, Dai, Kimchi, Eric T., Kaifi, Jussuf T., Qi, Xiaoqiang, Manjunath, Yariswamy, Liu, Xinjian, Deering, Tye, Avella, Diego M., Fox, Todd, Rockey, Don C., Schell, Todd D., Kester, Mark, Staveley-O’Carroll, Kevin F.
Publicado 2018

Glucosylceramidase Maintains Influenza Virus Infection by Regulating Endocytosis

por Drews, Kelly, Calgi, Michael P., Harrison, William Casey, Drews, Camille M., Costa-Pinheiro, Pedro, Shaw, Jeremy Joseph Porter, Jobe, Kendra A., Nelson, Elizabeth A., Han, John D., Fox, Todd, White, Judith M., Kester, Mark
Publicado 2019

Engraftment of Human Primary Acute Myeloid Leukemia Defined by Integrated Genetic Profiling in NOD/SCID/IL2rγnull Mice for Preclinical Ceramide-Based Therapeutic Evaluation

por Barth, Brian M, Keasey, Nichole R, Wang, Xujung, Shanmugavelandy, Sriram S, Rampal, Raajit, Hricik, Todd, Cabot, Myles C, Kester, Mark, Wang, Hong-Gang, Shultz, Leonard D, Tallman, Martin S, Levine, Ross L, Loughran, Thomas P, Claxton, David F
Publicado 2014

DJ4 Targets the Rho-Associated Protein Kinase Pathway and Attenuates Disease Progression in Preclinical Murine Models of Acute Myeloid Leukemia

por Golla, Upendarrao, Ehudin, Melanie A., Annageldiyev, Charyguly, Zeng, Zheng, Bastihalli Tukaramrao, Diwakar, Tarren, Anna, Date, Abhijit A., Elcheva, Irina, Berg, Arthur, Amin, Shantu, Loughran, Thomas P., Kester, Mark, Desai, Dhimant, Dovat, Sinisa, Claxton, David, Sharma, Arati
Publicado 2021

PP2A modulation overcomes multidrug resistance in chronic lymphocytic leukemia via mPTP-dependent apoptosis

por Jayappa, Kallesh D., Tran, Brian, Gordon, Vicki L., Morris, Christopher, Saha, Shekhar, Farrington, Caroline C., O’Connor, Caitlin M., Zawacki, Kaitlin P., Isaac, Krista M., Kester, Mark, Bender, Timothy P., Williams, Michael E., Portell, Craig A., Weber, Michael J., Narla, Goutham
Publicado 2023

C6-Ceramide Nanoliposomes Target the Warburg Effect in Chronic Lymphocytic Leukemia

por Ryland, Lindsay K., Doshi, Ushma A., Shanmugavelandy, Sriram S., Fox, Todd E., Aliaga, Cesar, Broeg, Kathleen, Baab, Kendall Thomas, Young, Megan, Khan, Osman, Haakenson, Jeremy K., Jarbadan, Nancy Ruth, Liao, Jason, Wang, Hong-Gang, Feith, David J., Loughran Jr, Thomas P., Liu, Xin, Kester, Mark
Publicado 2013

Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH

por Zanieri, Francesca, Levi, Ana, Montefusco, David, Longato, Lisa, De Chiara, Francesco, Frenguelli, Luca, Omenetti, Sara, Andreola, Fausto, Luong, Tu Vinh, Massey, Veronica, Caballeria, Juan, Fondevila, Constantino, Shanmugavelandy, Sriram S, Fox, Todd, Mazza, Giuseppe, Argemi, Josepmaria, Bataller, Ramon, Cowart, Lauren Ashley, Kester, Mark, Pinzani, Massimo, Rombouts, Krista
Publicado 2020

Ceramide nanoliposomes augment the efficacy of venetoclax and cytarabine in models of acute myeloid leukemia

por Khokhlatchev, Andrei V., Sharma, Arati, Deering, Tye G., Shaw, Jeremy J. P., Costa‐Pinheiro, Pedro, Golla, Upendarrao, Annageldiyev, Charyguly, Cabot, Myles C., Conaway, Mark R., Tan, Su‐Fern, Ung, Johnson, Feith, David J., Loughran, Thomas P., Claxton, David F., Fox, Todd E., Kester, Mark
Publicado 2022