Reprogramming of Virus-specific T Cells into Leukemia-reactive T Cells Using T Cell Receptor Gene Transfer

por Heemskerk, Mirjam H.M., Hoogeboom, Manja, Hagedoorn, Renate, Kester, Michel G.D., Willemze, Roel, Falkenburg, J.H. Frederik
Publicado 2004

Accurate prediction of HLA class II antigen presentation across all loci using tailored data acquisition and refined machine learning

por Nilsson, Jonas B., Kaabinejadian, Saghar, Yari, Hooman, Kester, Michel G. D., van Balen, Peter, Hildebrand, William H., Nielsen, Morten
Publicado 2023

Hematopoietic stem cell-derived myeloid and plasmacytoid DC-based vaccines are highly potent inducers of tumor-reactive T cell and NK cell responses ex vivo

por Thordardottir, Soley, Schaap, Nicolaas, Louer, Elja, Kester, Michel G. D., Falkenburg, J. H. Frederik, Jansen, Joop, Radstake, Timothy R. D., Hobo, Willemijn, Dolstra, Harry
Publicado 2017

High-Throughput Identification of Potential Minor Histocompatibility Antigens by MHC Tetramer-Based Screening: Feasibility and Limitations

por Hombrink, Pleun, Hadrup, Sine R., Bakker, Arne, Kester, Michel G. D., Falkenburg, J. H. Frederik, von dem Borne, Peter A., Schumacher, Ton N. M., Heemskerk, Mirjam H. M.
Publicado 2011

HSPVdb—the Human Short Peptide Variation Database for improved mass spectrometry-based detection of polymorphic HLA-ligands

por Nijveen, Harm, Kester, Michel G. D., Hassan, Chopie, Viars, Aurélie, de Ru, Arnoud H., de Jager, Machiel, Falkenburg, J. H. Fred, Leunissen, Jack A. M., van Veelen, Peter A.
Publicado 2010

A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer

por Jahn, Lorenz, Hagedoorn, Renate S., van der Steen, Dirk M., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado 2016

Generation of CD20-specific TCRs for TCR gene therapy of CD20(low) B-cell malignancies insusceptible to CD20-targeting antibodies

por Jahn, Lorenz, van der Steen, Dirk M., Hagedoorn, Renate S., Hombrink, Pleun, Kester, Michel G.D., Schoonakker, Marjolein P., de Ridder, Daniëlle, van Veelen, Peter A., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado 2016

Promiscuous Binding of Invariant Chain-Derived CLIP Peptide to Distinct HLA-I Molecules Revealed in Leukemic Cells

por van Luijn, Marvin M., van de Loosdrecht, Arjan A., Lampen, Margit H., van Veelen, Peter A., Zevenbergen, Adri, Kester, Michel G. D., de Ru, Arnoud H., Ossenkoppele, Gert J., van Hall, Thorbald, van Ham, S. Marieke
Publicado 2012

Promiscuity of Peptides Presented in HLA-DP Molecules from Different Immunogenicity Groups Is Associated With T-Cell Cross-Reactivity

por Laghmouchi, Aicha, Kester, Michel G. D., Hoogstraten, Conny, Hageman, Lois, de Klerk, Wendy, Huisman, Wesley, Koster, Eva A. S., de Ru, Arnoud H., van Balen, Peter, Klobuch, Sebastian, van Veelen, Peter A., Falkenburg, J. H. Frederik, Jedema, Inge
Publicado 2022

Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8(+) T cells for adoptive immunotherapy

por Mousset, Charlotte M., Hobo, Willemijn, Ji, Yun, Fredrix, Hanny, De Giorgi, Valeria, Allison, Robert D., Kester, Michel G. D., Falkenburg, J. H. Frederik, Schaap, Nicolaas P. M., Jansen, Joop H., Gattinoni, Luca, Dolstra, Harry, van der Waart, Anniek B.
Publicado 2018

Islet-Specific CTL Cloned from a Type 1 Diabetes Patient Cause Beta-Cell Destruction after Engraftment into HLA-A2 Transgenic NOD/SCID/IL2RG Null Mice

por Unger, Wendy W. J., Pearson, Todd, Abreu, Joana R. F., Laban, Sandra, van der Slik, Arno R., der Kracht, Sacha Mulder-van, Kester, Michel G. D., Serreze, Dave V., Shultz, Leonard D., Griffioen, Marieke, Drijfhout, Jan Wouter, Greiner, Dale L., Roep, Bart O.
Publicado 2012

Human T cells recognize HLA-DP–bound peptides in two orientations

por Klobuch, Sebastian, Lim, Jia Jia, van Balen, Peter, Kester, Michel G. D., de Klerk, Wendy, de Ru, Arnoud H., Pothast, Cilia R., Jedema, Inge, Drijfhout, Jan W., Rossjohn, Jamie, Reid, Hugh H., van Veelen, Peter A., Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado 2022

Human CD34(+)-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8(+) T cell and NK cell responses in vitro and in vivo

por van Eck van der Sluijs, Jesper, van Ens, Diede, Brummelman, Jolanda, Heister, Daan, Sareen, Aastha, Truijen, Lisa, van Ingen Schenau, Dorette S., Heemskerk, Mirjam H. M., Griffioen, Marieke, Kester, Michel G. D., Schaap, Nicolaas P. M., Jansen, Joop H., van der Waart, Anniek B., Dolstra, Harry, Hobo, Willemijn
Publicado 2023

Efficient Identification of Novel Hla-A*0201–Presented Cytotoxic T Lymphocyte Epitopes in the Widely Expressed Tumor Antigen Prame by Proteasome-Mediated Digestion Analysis

por Kessler, Jan H., Beekman, Nico J., Bres-Vloemans, Sandra A., Verdijk, Pauline, van Veelen, Peter A., Kloosterman-Joosten, Antoinette M., Vissers, Debby C.J., ten Bosch, George J.A., Kester, Michel G.D., Sijts, Alice, Drijfhout, Jan Wouter, Ossendorp, Ferry, Offringa, Rienk, Melief, Cornelis J.M.
Publicado 2001

WT1-specific TCRs directed against newly identified peptides install antitumor reactivity against acute myeloid leukemia and ovarian carcinoma

por van Amerongen, Rosa A, Hagedoorn, Renate S, Remst, Dennis F G, Assendelft, Danique C, van der Steen, Dirk M, Wouters, Anne K, van de Meent, Marian, Kester, Michel G D, de Ru, Arnoud H, Griffioen, Marieke, van Veelen, Peter A, Falkenburg, J H Frederik, Heemskerk, Mirjam H M
Publicado 2022

Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain

por Meeuwsen, Miranda H., Wouters, Anne K., Wachsmann, Tassilo L. A., Hagedoorn, Renate S., Kester, Michel G. D., Remst, Dennis F. G., van der Steen, Dirk M., de Ru, Arnoud H., van Hees, Els P., Kremer, Martijn, Griffioen, Marieke, van Veelen, Peter A., Falkenburg, J. H. Frederik, Heemskerk, Mirjam H. M.
Publicado 2023

A library of cancer testis specific T cell receptors for T cell receptor gene therapy

por de Rooij, Marije A.J., Remst, Dennis F.G., van der Steen, Dirk M., Wouters, Anne K., Hagedoorn, Renate S., Kester, Michel G.D., Meeuwsen, Miranda H., Wachsmann, Tassilo L.A., de Ru, Arnoud H., van Veelen, Peter A., Verdegaal, Els M.E., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado 2023

Clinically applicable CD34(+)-derived blood dendritic cell subsets exhibit key subset-specific features and potently boost anti-tumor T and NK cell responses

por van Eck van der Sluijs, Jesper, van Ens, Diede, Thordardottir, Soley, Vodegel, Denise, Hermens, Inge, van der Waart, Anniek B., Falkenburg, J. H. Frederik, Kester, Michel G. D., de Rink, Iris, Heemskerk, Mirjam H. M., Borst, Jannie, Schaap, Nicolaas P. M., Jansen, Joop H., Xiao, Yanling, Dolstra, Harry, Hobo, Willemijn
Publicado 2021

A library of cancer testis specific T cell receptors for T cell receptor gene therapy

por de Rooij, Marije A.J., Remst, Dennis F.G., van der Steen, Dirk M., Wouters, Anne K., Hagedoorn, Renate S., Kester, Michel G.D., Meeuwsen, Miranda H., Wachsmann, Tassilo L.A., de Ru, Arnoud H., van Veelen, Peter A., Verdegaal, Els M.E., Falkenburg, J.H. Frederik, Heemskerk, Mirjam H.M.
Publicado 2022

An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML

por van der Lee, Dyantha I., Koutsoumpli, Georgia, Reijmers, Rogier M., Honders, M. Willy, de Jong, Rob C. M., Remst, Dennis F. G., Wachsmann, Tassilo L. A., Hagedoorn, Renate S., Franken, Kees L. M. C., Kester, Michel G. D., Harber, Karl J., Roelofsen, Lisanne M., Schouten, Annemiek M., Mulder, Arend, Drijfhout, Jan W., Veelken, Hendrik, van Veelen, Peter A., Heemskerk, Mirjam H. M., Falkenburg, J. H. Frederik, Griffioen, Marieke
Publicado 2021