Using a birth cohort to study brain health and preclinical dementia: recruitment and participation rates in Insight 46

por James, Sarah-Naomi, Lane, Christopher A., Parker, Thomas D., Lu, Kirsty, Collins, Jessica D., Murray-Smith, Heidi, Byford, Michelle, Wong, Andrew, Keshavan, Ashvini, Buchanan, Sarah, Keuss, Sarah E., Kuh, Diana, Fox, Nick C., Schott, Jonathan M., Richards, Marcus
Publicado 2018

Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays

por Keshavan, Ashvini, Wellington, Henrietta, Chen, Zhongbo, Khatun, Ayesha, Chapman, Miles, Hart, Melanie, Cash, David M., Coath, William, Parker, Thomas D., Buchanan, Sarah M., Keuss, Sarah E., Harris, Matthew J., Murray‐Smith, Heidi, Heslegrave, Amanda, Fox, Nick C., Zetterberg, Henrik, Schott, Jonathan M.
Publicado 2020

Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays

por Keshavan, Ashvini, Wellington, Henrietta, Chen, Zhongbo, Khatun, Ayesha, Chapman, Miles, Hart, Melanie, Cash, David M., Coath, William, Parker, Thomas D., Buchanan, Sarah M., Keuss, Sarah E., Harris, Matthew J., Murray‐Smith, Heidi, Heslegrave, Amanda, Fox, Nick C., Zetterberg, Henrik, Schott, Jonathan M
Publicado 2021

Subjective cognitive complaints at age 70: associations with amyloid and mental health

por Pavisic, Ivanna M., Lu, Kirsty, Keuss, Sarah E., James, Sarah-Naomi, Lane, Christopher A., Parker, Thomas D., Keshavan, Ashvini, Buchanan, Sarah M., Murray-Smith, Heidi, Cash, David M., Coath, William, Wong, Andrew, Fox, Nick C., Crutch, Sebastian J., Richards, Marcus, Schott, Jonathan M.
Publicado 2021

Olfactory testing does not predict β-amyloid, MRI measures of neurodegeneration or vascular pathology in the British 1946 birth cohort

por Buchanan, Sarah M., Parker, Thomas D., Lane, Christopher A., Keshavan, Ashvini, Keuss, Sarah E., Lu, Kirsty, James, Sarah-Naomi, Murray-Smith, Heidi, Wong, Andrew, Nicholas, Jennifer, Cash, David M., Malone, Ian B., Coath, William, Thomas, David L., Sudre, Carole, Fox, Nick C., Richards, Marcus, Schott, Jonathan M.
Publicado 2020

Incidental findings on brain imaging and blood tests: results from the first phase of Insight 46, a prospective observational substudy of the 1946 British birth cohort

por Keuss, Sarah E, Parker, Thomas D, Lane, Christopher A, Hoskote, Chandrashekar, Shah, Sachit, Cash, David M, Keshavan, Ashvini, Buchanan, Sarah M, Murray-Smith, Heidi, Wong, Andrew, James, Sarah-Naomi, Lu, Kirsty, Collins, Jessica, Beasley, Daniel G, Malone, Ian B, Thomas, David L, Barnes, Anna, Richards, Marcus, Fox, Nick, Schott, Jonathan M
Publicado 2019

Amyloid β influences the relationship between cortical thickness and vascular load

por Parker, Thomas D., Cash, David M., Lane, Christopher A., Lu, Kirsty, Malone, Ian B., Nicholas, Jennifer M., James, Sarah‐Naomi, Keshavan, Ashvini, Murray‐Smith, Heidi, Wong, Andrew, Buchanan, Sarah M., Keuss, Sarah E., Sudre, Carole H., Thomas, David L., Crutch, Sebastian J., Fox, Nick C., Richards, Marcus, Schott, Jonathan M.
Publicado 2020

Hippocampal subfield volumes and pre-clinical Alzheimer’s disease in 408 cognitively normal adults born in 1946

por Parker, Thomas D., Cash, David M., Lane, Christopher A. S., Lu, Kirsty, Malone, Ian B., Nicholas, Jennifer M., James, Sarah-Naomi, Keshavan, Ashvini, Murray-Smith, Heidi, Wong, Andrew, Buchanan, Sarah M., Keuss, Sarah E., Sudre, Carole H., Modat, Marc, Thomas, David L., Crutch, Sebastian J., Richards, Marcus, Fox, Nick C., Schott, Jonathan M.
Publicado 2019

Increased variability in reaction time is associated with amyloid beta pathology at age 70

por Lu, Kirsty, Nicholas, Jennifer M., James, Sarah‐Naomi, Lane, Christopher A., Parker, Thomas D., Keshavan, Ashvini, Keuss, Sarah E., Buchanan, Sarah M., Murray‐Smith, Heidi, Cash, David M., Sudre, Carole H., Malone, Ian B., Coath, William, Wong, Andrew, Henley, Susie M.D., Fox, Nick C., Richards, Marcus, Schott, Jonathan M., Crutch, Sebastian J.
Publicado 2020

Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort

por Lane, Christopher A., Barnes, Josephine, Nicholas, Jennifer M., Sudre, Carole H., Cash, David M., Malone, Ian B., Parker, Thomas D., Keshavan, Ashvini, Buchanan, Sarah M., Keuss, Sarah E., James, Sarah-Naomi, Lu, Kirsty, Murray-Smith, Heidi, Wong, Andrew, Gordon, Elizabeth, Coath, William, Modat, Marc, Thomas, David, Richards, Marcus, Fox, Nick C., Schott, Jonathan M.
Publicado 2019

Adulthood cognitive trajectories over 26 years and brain health at 70 years of age: findings from the 1946 British Birth Cohort

por James, Sarah-Naomi, Nicholas, Jennifer M., Lu, Kirsty, Keshavan, Ashvini, Lane, Christopher A., Parker, Thomas, Buchanan, Sarah M., Keuss, Sarah E., Murray-Smith, Heidi, Wong, Andrew, Cash, David M., Malone, Ian B., Barnes, Josephine, Sudre, Carole H., Coath, William, Modat, Marc, Ourselin, Sebastien, Crutch, Sebastian J., Kuh, Diana, Fox, Nick C., Schott, Jonathan M., Richards, Marcus
Publicado 2023

Cognition at age 70: Life course predictors and associations with brain pathologies

por Lu, Kirsty, Nicholas, Jennifer M., Collins, Jessica D., James, Sarah-Naomi, Parker, Thomas D., Lane, Christopher A., Keshavan, Ashvini, Keuss, Sarah E., Buchanan, Sarah M., Murray-Smith, Heidi, Cash, David M., Sudre, Carole H., Malone, Ian B., Coath, William, Wong, Andrew, Henley, Susie M.D., Crutch, Sebastian J., Fox, Nick C., Richards, Marcus, Schott, Jonathan M.
Publicado 2019

Operationalizing the centiloid scale for [(18)F]florbetapir PET studies on PET/MRI

por Coath, William, Modat, Marc, Cardoso, M. Jorge, Markiewicz, Pawel J., Lane, Christopher A., Parker, Thomas D., Keshavan, Ashvini, Buchanan, Sarah M., Keuss, Sarah E., Harris, Matthew J., Burgos, Ninon, Dickson, John, Barnes, Anna, Thomas, David L., Beasley, Daniel, Malone, Ian B., Wong, Andrew, Erlandsson, Kjell, Thomas, Benjamin A., Schöll, Michael, Ourselin, Sebastien, Richards, Marcus, Fox, Nick C., Schott, Jonathan M., Cash, David M.
Publicado 2023

Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epid...

por Lane, Christopher A, Barnes, Josephine, Nicholas, Jennifer M, Sudre, Carole H, Cash, David M, Parker, Thomas D, Malone, Ian B, Lu, Kirsty, James, Sarah-Naomi, Keshavan, Ashvini, Murray-Smith, Heidi, Wong, Andrew, Buchanan, Sarah M, Keuss, Sarah E, Gordon, Elizabeth, Coath, William, Barnes, Anna, Dickson, John, Modat, Marc, Thomas, David, Crutch, Sebastian J, Hardy, Rebecca, Richards, Marcus, Fox, Nick C, Schott, Jonathan M
Publicado 2019

Visuomotor integration deficits are common to familial and sporadic preclinical Alzheimer’s disease

por Lu, Kirsty, Nicholas, Jennifer M, Weston, Philip S J, Stout, Julie C, O’Regan, Alison M, James, Sarah-Naomi, Buchanan, Sarah M, Lane, Christopher A, Parker, Thomas D, Keuss, Sarah E, Keshavan, Ashvini, Murray-Smith, Heidi, Cash, David M, Sudre, Carole H, Malone, Ian B, Coath, William, Wong, Andrew, Richards, Marcus, Henley, Susie M D, Fox, Nick C, Schott, Jonathan M, Crutch, Sebastian J
Publicado 2021

Population-based blood screening for preclinical Alzheimer’s disease in a British birth cohort at age 70

por Keshavan, Ashvini, Pannee, Josef, Karikari, Thomas K, Rodriguez, Juan Lantero, Ashton, Nicholas J, Nicholas, Jennifer M, Cash, David M, Coath, William, Lane, Christopher A, Parker, Thomas D, Lu, Kirsty, Buchanan, Sarah M, Keuss, Sarah E, James, Sarah-Naomi, Murray-Smith, Heidi, Wong, Andrew, Barnes, Anna, Dickson, John C, Heslegrave, Amanda, Portelius, Erik, Richards, Marcus, Fox, Nick C, Zetterberg, Henrik, Blennow, Kaj, Schott, Jonathan M
Publicado 2021

A population‐based study of head injury, cognitive function and pathological markers

por James, Sarah‐Naomi, Nicholas, Jennifer M., Lane, Christopher A., Parker, Thomas D., Lu, Kirsty, Keshavan, Ashvini, Buchanan, Sarah M., Keuss, Sarah E., Murray‐Smith, Heidi, Wong, Andrew, Cash, David M., Malone, Ian B., Barnes, Josephine, Sudre, Carole H., Coath, William, Prosser, Lloyd, Ourselin, Sebastien, Modat, Marc, Thomas, David L., Cardoso, Jorge, Heslegrave, Amanda, Zetterberg, Henrik, Crutch, Sebastian J., Schott, Jonathan M., Richards, Marcus, Fox, Nick C.
Publicado 2021

Neuroimaging, clinical and life course correlates of normal-appearing white matter integrity in 70-year-olds

por James, Sarah-Naomi, Manning, Emily N, Storey, Mathew, Nicholas, Jennifer M, Coath, William, Keuss, Sarah E, Cash, David M, Lane, Christopher A, Parker, Thomas, Keshavan, Ashvini, Buchanan, Sarah M, Wagen, Aaron, Harris, Mathew, Malone, Ian, Lu, Kirsty, Needham, Louisa P, Street, Rebecca, Thomas, David, Dickson, John, Murray-Smith, Heidi, Wong, Andrew, Freiberger, Tamar, Crutch, Sebastian J, Fox, Nick C, Richards, Marcus, Barkhof, Frederik, Sudre, Carole H, Barnes, Josephine, Schott, Jonathan M
Publicado 2023

Associations of β-Amyloid and Vascular Burden With Rates of Neurodegeneration in Cognitively Normal Members of the 1946 British Birth Cohort

por Keuss, Sarah E., Coath, William, Nicholas, Jennifer M., Poole, Teresa, Barnes, Josephine, Cash, David M., Lane, Christopher A., Parker, Thomas D., Keshavan, Ashvini, Buchanan, Sarah M., Wagen, Aaron Z., Storey, Mathew, Harris, Matthew, Malone, Ian B., Sudre, Carole H., Lu, Kirsty, James, Sarah-Naomi, Street, Rebecca, Thomas, David L., Dickson, John C., Murray-Smith, Heidi, Wong, Andrew, Freiberger, Tamar, Crutch, Sebastian, Richards, Marcus, Fox, Nick C., Schott, Jonathan M.
Publicado 2022

Life course, genetic, and neuropathological associations with brain age in the 1946 British Birth Cohort: a population-based study

por Wagen, Aaron Z, Coath, William, Keshavan, Ashvini, James, Sarah-Naomi, Parker, Thomas D, Lane, Christopher A, Buchanan, Sarah M, Keuss, Sarah E, Storey, Mathew, Lu, Kirsty, Macdougall, Amy, Murray-Smith, Heidi, Freiberger, Tamar, Cash, David M, Malone, Ian B, Barnes, Josephine, Sudre, Carole H, Wong, Andrew, Pavisic, Ivanna M, Street, Rebecca, Crutch, Sebastian J, Escott-Price, Valentina, Leonenko, Ganna, Zetterberg, Henrik, Wellington, Henrietta, Heslegrave, Amanda, Barkhof, Frederik, Richards, Marcus, Fox, Nick C, Cole, James H, Schott, Jonathan M
Publicado 2022