Colloidal aggregation confounds cell-based Covid-19 antiviral screens

por Glenn, Isabella S., Hall, Lauren N., Khalid, Mir M., Ott, Melanie, Shoichet, Brian K.
Publicado 2023

SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells

por Kim, Ik-Jung, Lee, Yong-ho, Khalid, Mir M., Chen, Irene P., Zhang, Yini, Ott, Melanie, Verdin, Eric
Publicado 2023

Toll‐like receptor‐4 299Gly allele is associated with Guillain‐Barré syndrome in Bangladesh

por Jahan, Israt, Ahammad, Rijwan U., Khalid, Mir M., Rahman, Mohammad I., Hayat, Shoma, Islam, Badrul, Mohammad, Quazi D., Islam, Zhahirul
Publicado 2019

Association of mannose-binding lectin 2 gene polymorphisms with Guillain-Barré syndrome

por Jahan, Israt, Hayat, Shoma, Khalid, Mir M., Ahammad, Rijwan U., Asad, Asaduzzaman, Islam, Badrul, Mohammad, Quazi D., Jacobs, Bart C., Islam, Zhahirul
Publicado 2022

The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein

por Fontaine, Krystal A., Leon, Kristoffer E., Khalid, Mir M., Tomar, Sakshi, Jimenez-Morales, David, Dunlap, Mariah, Kaye, Julia A., Shah, Priya S., Finkbeiner, Steve, Krogan, Nevan J., Ott, Melanie
Publicado 2018

Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles

por Syed, Abdullah M., Taha, Taha Y., Tabata, Takako, Chen, Irene P., Ciling, Alison, Khalid, Mir M., Sreekumar, Bharath, Chen, Pei-Yi, Hayashi, Jennifer M., Soczek, Katarzyna M., Ott, Melanie, Doudna, Jennifer A.
Publicado 2021

Nuclear accumulation of host transcripts during Zika Virus Infection

por Leon, Kristoffer E., Khalid, Mir M., Flynn, Ryan A., Fontaine, Krystal A., Nguyen, Thong T., Kumar, G. Renuka, Simoneau, Camille R., Tomar, Sakshi, Jimenez-Morales, David, Dunlap, Mariah, Kaye, Julia, Shah, Priya S., Finkbeiner, Steven, Krogan, Nevan J., Bertozzi, Carolyn, Carette, Jan E., Ott, Melanie
Publicado 2023

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

por Syed, Abdullah M., Ciling, Alison, Khalid, Mir M., Sreekumar, Bharath, Chen, Pei-Yi, Kumar, G. Renuka, Silva, Ines, Milbes, Bilal, Kojima, Noah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Spraggon, Lee, Taha, Taha Y., Tabata, Takako, Chen, Irene P., Ott, Melanie, Doudna, Jennifer A.
Publicado 2022

Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles

por Syed, Abdullah M., Ciling, Alison, Taha, Taha Y., Chen, Irene P., Khalid, Mir M., Sreekumar, Bharath, Chen, Pei-Yi, Kumar, G. Renuka, Suryawanshi, Rahul, Silva, Ines, Milbes, Bilal, Kojima, Noah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Spraggon, Lee, Tabata, Takako, Ott, Melanie, Doudna, Jennifer A.
Publicado 2022

Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6

por Taha, Taha Y., Chen, Irene P., Hayashi, Jennifer M., Tabata, Takako, Walcott, Keith, Kimmerly, Gabriella R., Syed, Abdullah M., Ciling, Alison, Suryawanshi, Rahul K., Martin, Hannah S., Bach, Bryan H., Tsou, Chia-Lin, Montano, Mauricio, Khalid, Mir M., Sreekumar, Bharath K., Renuka Kumar, G., Wyman, Stacia, Doudna, Jennifer A., Ott, Melanie
Publicado 2023

Neutralizing immunity in vaccine breakthrough infections from the SARS-CoV-2 Omicron and Delta variants

por Servellita, Venice, Syed, Abdullah M., Morris, Mary Kate, Brazer, Noah, Saldhi, Prachi, Garcia-Knight, Miguel, Sreekumar, Bharath, Khalid, Mir M., Ciling, Alison, Chen, Pei-Yi, Kumar, G. Renuka, Gliwa, Amelia S., Nguyen, Jenny, Sotomayor-Gonzalez, Alicia, Zhang, Yueyuan, Frias, Edwin, Prostko, John, Hackett, John, Andino, Raul, Wadford, Debra A., Hanson, Carl, Doudna, Jennifer, Ott, Melanie, Chiu, Charles Y.
Publicado 2022

Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2

por Chen, Irene P., Longbotham, James E., McMahon, Sarah, Suryawanshi, Rahul K., Khalid, Mir M., Taha, Taha Y., Tabata, Takako, Hayashi, Jennifer M., Soveg, Frank W., Carlson-Stevermer, Jared, Gupta, Meghna, Zhang, Meng Yao, Lam, Victor L., Li, Yang, Yu, Zanlin, Titus, Erron W., Diallo, Amy, Oki, Jennifer, Holden, Kevin, Krogan, Nevan, Fujimori, Danica Galonić, Ott, Melanie
Publicado 2022

NF-κB inhibitor alpha has a cross-variant role during SARS-CoV-2 infection in ACE2-overexpressing human airway organoids

por Simoneau, Camille R., Chen, Pei-Yi, Xing, Galen K., Khalid, Mir M., Meyers, Nathan L., Hayashi, Jennifer M., Taha, Taha Y., Leon, Kristoffer E., Ashuach, Tal, Fontaine, Krystal A., Rodriguez, Lauren, Joehnk, Bastian, Walcott, Keith, Vasudevan, Sreelakshmi, Fang, Xiaohui, Maishan, Mazharul, Schultz, Shawn, Roose, Jeroen, Matthay, Michael A., Sil, Anita, Arjomandi, Mehrdad, Yosef, Nir, Ott, Melanie
Publicado 2022

Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination

por Suryawanshi, Rahul K., Taha, Taha Y., McCavitt-Malvido, Maria, Silva, Ines, Khalid, Mir M., Syed, Abdullah M., Chen, Irene P., Saldhi, Prachi, Sreekumar, Bharath, Montano, Mauricio, Foresythe, Kafaya, Tabata, Takako, Kumar, G. Renuka, Sotomayor-Gonzalez, Alicia, Servellita, Venice, Gliwa, Amelia, Nguyen, Jenny, Kojima, Noah, Arellanor, Teresa, Bussanich, Aallyah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Wang, Yuzhu, Ghazarian, Sydney, Davis, Gregg, Rodriguez, Diviana, Doudna, Jennifer, Spraggon, Lee, Chiu, Charles Y., Ott, Melanie
Publicado 2023

Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination

por Suryawanshi, Rahul K., Chen, Irene P., Ma, Tongcui, Syed, Abdullah M., Brazer, Noah, Saldhi, Prachi, Simoneau, Camille R., Ciling, Alison, Khalid, Mir M., Sreekumar, Bharath, Chen, Pei-Yi, Kumar, G. Renuka, Montano, Mauricio, Gascon, Ronne, Tsou, Chia-Lin, Garcia-Knight, Miguel A., Sotomayor-Gonzalez, Alicia, Servellita, Venice, Gliwa, Amelia, Nguyen, Jenny, Silva, Ines, Milbes, Bilal, Kojima, Noah, Hess, Victoria, Shacreaw, Maria, Lopez, Lauren, Brobeck, Matthew, Turner, Fred, Soveg, Frank W., George, Ashley F., Fang, Xiaohui, Maishan, Mazharul, Matthay, Michael, Morris, Mary Kate, Wadford, Debra, Hanson, Carl, Greene, Warner C., Andino, Raul, Spraggon, Lee, Roan, Nadia R., Chiu, Charles Y., Doudna, Jennifer A., Ott, Melanie
Publicado 2022

SARS-CoV-2 infection of airway organoids reveals conserved use of Tetraspanin-8 by Ancestral, Delta, and Omicron variants

por Hysenaj, Lisiena, Little, Samantha, Kulhanek, Kayla, Magnen, Melia, Bahl, Kriti, Gbenedio, Oghenekevwe M., Prinz, Morgan, Rodriguez, Lauren, Andersen, Christopher, Rao, Arjun Arkal, Shen, Alan, Lone, Jean-Christophe, Lupin-Jimenez, Leonard C., Bonser, Luke R., Serwas, Nina K., Mick, Eran, Khalid, Mir M., Taha, Taha Y., Kumar, Renuka, Li, Jack Z., Ding, Vivianne W., Matsumoto, Shotaro, Maishan, Mazharul, Sreekumar, Bharath, Simoneau, Camille, Nazarenko, Irina, Tomlinson, Michael G., Khan, Khajida, von Gottberg, Anne, Sigal, Alex, Looney, Mark R., Fragiadakis, Gabriela K., Jablons, David M., Langelier, Charles R., Matthay, Michael, Krummel, Matthew, Erle, David J., Combes, Alexis J., Sil, Anita, Ott, Melanie, Kratz, Johannes R., Roose, Jeroen P.
Publicado 2023

Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

por Deng, Xianding, Garcia-Knight, Miguel A, Khalid, Mir M., Servellita, Venice, Wang, Candace, Morris, Mary Kate, Sotomayor-González, Alicia, Glasner, Dustin R, Reyes, Kevin R, Gliwa, Amelia S., Reddy, Nikitha P., Martin, Claudia Sanchez San, Federman, Scot, Cheng, Jing, Balcerek, Joanna, Taylor, Jordan, Streithorst, Jessica A, Miller, Steve, Kumar, G. Renuka, Sreekumar, Bharath, Chen, Pei-Yi, Schulze-Gahmen, Ursula, Taha, Taha Y., Hayashi, Jennifer, Simoneau, Camille R., McMahon, Sarah, Lidsky, Peter V., Xiao, Yinghong, Hemarajata, Peera, Green, Nicole M., Espinosa, Alex, Kath, Chantha, Haw, Monica, Bell, John, Hacker, Jill K., Hanson, Carl, Wadford, Debra A., Anaya, Carlos, Ferguson, Donna, Lareau, Liana F., Frankino, Phillip A., Shivram, Haridha, Wyman, Stacia K., Ott, Melanie, Andino, Raul, Chiu, Charles Y.
Publicado 2021

Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

por Deng, Xianding, Garcia-Knight, Miguel A., Khalid, Mir M., Servellita, Venice, Wang, Candace, Morris, Mary Kate, Sotomayor-González, Alicia, Glasner, Dustin R., Reyes, Kevin R., Gliwa, Amelia S., Reddy, Nikitha P., Sanchez San Martin, Claudia, Federman, Scot, Cheng, Jing, Balcerek, Joanna, Taylor, Jordan, Streithorst, Jessica A., Miller, Steve, Sreekumar, Bharath, Chen, Pei-Yi, Schulze-Gahmen, Ursula, Taha, Taha Y., Hayashi, Jennifer M., Simoneau, Camille R., Kumar, G. Renuka, McMahon, Sarah, Lidsky, Peter V., Xiao, Yinghong, Hemarajata, Peera, Green, Nicole M., Espinosa, Alex, Kath, Chantha, Haw, Monica, Bell, John, Hacker, Jill K., Hanson, Carl, Wadford, Debra A., Anaya, Carlos, Ferguson, Donna, Frankino, Phillip A., Shivram, Haridha, Lareau, Liana F., Wyman, Stacia K., Ott, Melanie, Andino, Raul, Chiu, Charles Y.
Publicado 2021

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

por Gordon, David E., Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V., Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S., Obernier, Kirsten, Guo, Jeffrey Z., Batra, Jyoti, Kaake, Robyn M., Weckstein, Andrew R., Owens, Tristan W., Gupta, Meghna, Pourmal, Sergei, Titus, Erron W., Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O’Meara, Matthew J., Tummino, Tia A., Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L., Fabius, Jacqueline M., Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M., Naing, Zun Zar Chi, Pulido, Ernst H., Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A., Azumaya, Caleigh M., Billesbølle, Christian, Brilot, Axel F., Campbell, Melody G., Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T., Liu, Yanxin, Merz, Gregory E., Moritz, Michelle, Nguyen, Henry C., Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N., Schulze-Gahmen, Ursula, Smith, Amber M., Sun, Ming, Young, Iris D., Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R., Chen, Jen, Chio, Cynthia M., Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L., Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E., Melo, Arthur A., Moss, Frank R., Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K., Pospiech, Thomas H., Safari, Maliheh, Sangwan, Smriti, Schaefer, Kaitlin, Thomas, Paul V., Thwin, Aye C., Trenker, Raphael, Tse, Eric, Tsui, Tsz Kin Martin, Wang, Feng, Whitis, Natalie, Yu, Zanlin, Zhang, Kaihua, Zhang, Yang, Zhou, Fengbo, Saltzberg, Daniel, Hodder, Anthony J., Shun-Shion, Amber S., Williams, Daniel M., White, Kris M., Rosales, Romel, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Patel, Arvind H., Rihn, Suzannah, Khalid, Mir M., Vallejo-Gracia, Albert, Fozouni, Parinaz, Simoneau, Camille R., Roth, Theodore L., Wu, David, Karim, Mohd Anisul, Ghoussaini, Maya, Dunham, Ian, Berardi, Francesco, Weigang, Sebastian, Chazal, Maxime, Park, Jisoo, Logue, James, McGrath, Marisa, Weston, Stuart, Haupt, Robert, Hastie, C. James, Elliott, Matthew, Brown, Fiona, Burness, Kerry A., Reid, Elaine, Dorward, Mark, Johnson, Clare, Wilkinson, Stuart G., Geyer, Anna, Giesel, Daniel M., Baillie, Carla, Raggett, Samantha, Leech, Hannah, Toth, Rachel, Goodman, Nicola, Keough, Kathleen C., Lind, Abigail L., Klesh, Reyna J., Hemphill, Kafi R., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Maures, Travis, Pollard, Katherine S., Sali, Andrej, Agard, David A., Cheng, Yifan, Fraser, James S., Frost, Adam, Jura, Natalia, Kortemme, Tanja, Manglik, Aashish, Southworth, Daniel R., Stroud, Robert M., Alessi, Dario R., Davies, Paul, Frieman, Matthew B., Ideker, Trey, Abate, Carmen, Jouvenet, Nolwenn, Kochs, Georg, Shoichet, Brian, Ott, Melanie, Palmarini, Massimo, Shokat, Kevan M., García-Sastre, Adolfo, Rassen, Jeremy A., Grosse, Robert, Rosenberg, Oren S., Verba, Kliment A., Basler, Christopher F., Vignuzzi, Marco, Peden, Andrew A., Beltrao, Pedro, Krogan, Nevan J.
Publicado 2020