Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors

por Delcuve, Geneviève P, Khan, Dilshad H, Davie, James R
Publicado 2012

Mitogen-induced distinct epialleles are phosphorylated at either H3S10 or H3S28, depending on H3K27 acetylation

por Khan, Dilshad H., Healy, Shannon, He, Shihua, Lichtensztejn, Daniel, Klewes, Ludger, Sharma, Kiran L., Lau, Veronica, Mai, Sabine, Delcuve, Geneviève P., Davie, James R.
Publicado 2017

RNA-dependent dynamic histone acetylation regulates MCL1 alternative splicing

por Khan, Dilshad H., Gonzalez, Carolina, Cooper, Charlton, Sun, Jian-Min, Chen, Hou Yu, Healy, Shannon, Xu, Wayne, Smith, Karen T., Workman, Jerry L., Leygue, Etienne, Davie, James R.
Publicado 2014

MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells

por Bahat, Amir, Goldman, Andres, Zaltsman, Yehudit, Khan, Dilshad H., Halperin, Coral, Amzallag, Emmanuel, Krupalnik, Vladislav, Mullokandov, Michael, Silberman, Alon, Erez, Ayelet, Schimmer, Aaron D., Hanna, Jacob H., Gross, Atan
Publicado 2018

Venetoclax enhances T cell–mediated antileukemic activity by increasing ROS production

por Lee, Jong Bok, Khan, Dilshad H., Hurren, Rose, Xu, Mingjing, Na, Yoosu, Kang, Hyeonjeong, Mirali, Sara, Wang, Xiaoming, Gronda, Marcela, Jitkova, Yulia, MacLean, Neil, Arruda, Andrea, Alaniz, Zoe, Konopleva, Marina Y., Andreeff, Michael, Minden, Mark D., Zhang, Li, Schimmer, Aaron D.
Publicado 2021

IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells

por Nachmias, Boaz, Khan, Dilshad H., Voisin, Veronique, Mer, Arvind S., Thomas, Geethu Emily, Segev, Nadav, St-Germain, Jonathan, Hurren, Rose, Gronda, Marcela, Botham, Aaron, Wang, Xiaoming, Maclean, Neil, Seneviratne, Ayesh K., Duong, Nathan, Xu, Changjiang, Arruda, Andrea, Orouji, Elias, Algouneh, Arash, Hakem, Razqallah, Shlush, Liran, Minden, Mark D., Raught, Brian, Bader, Gary D., Schimmer, Aaron D.
Publicado 2022

The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness

por Thomas, Geethu Emily, Egan, Grace, García-Prat, Laura, Botham, Aaron, Voisin, Veronique, Patel, Parasvi S., Hoff, Fieke W., Chin, Jordan, Nachmias, Boaz, Kaufmann, Kerstin B., Khan, Dilshad H., Hurren, Rose, Wang, Xiaoming, Gronda, Marcela, MacLean, Neil, O’Brien, Cristiana, Singh, Rashim P., Jones, Courtney L., Harding, Shane M., Raught, Brian, Arruda, Andrea, Minden, Mark D., Bader, Gary D., Hakem, Razq, Kornblau, Steve, Dick, John E., Schimmer, Aaron D.
Publicado 2022