Synergism Potentiates Oxidative Antiproliferative Effects of Naringenin and Quercetin in MCF-7 Breast Cancer Cells

por Rhman, Mahasin Abdel, Devnarain, Nikita, Khan, Rene, Owira, Peter M. O.
Publicado 2022

Assessing the Potential Contribution of In Silico Studies in Discovering Drug Candidates That Interact with Various SARS-CoV-2 Receptors

por Mushebenge, Aganze Gloire-Aimé, Ugbaja, Samuel Chima, Mbatha, Nonkululeko Avril, B. Khan, Rene, Kumalo, Hezekiel M.
Publicado 2023

Genomic Investigation into the Virulome, Pathogenicity, Stress Response Factors, Clonal Lineages, and Phylogenetic Relationship of Escherichia coli Strains Isolated from Meat Sourc...

por Adzitey, Frederick, Asante, Jonathan, Kumalo, Hezekiel M., Khan, Rene B., Somboro, Anou M., Amoako, Daniel G.
Publicado 2020

Mechanistic Insights into Oxidative Stress and Apoptosis Mediated by Tannic Acid in Human Liver Hepatocellular Carcinoma Cells

por Mhlanga, Priscilla, Perumal, Pearl O., Somboro, Anou M., Amoako, Daniel G., Khumalo, Hezekiel M., Khan, Rene B.
Publicado 2019

Cytoproliferative and Anti-Oxidant Effects Induced by Tannic Acid in Human Embryonic Kidney (Hek-293) Cells

por Perumal, Pearl O., Mhlanga, Priscilla, Somboro, Anou M., Amoako, Daniel G., Khumalo, Hezekiel M., Khan, Rene M.
Publicado 2019

Heat Shock Protein 90 (HSP90) Inhibitors as Anticancer Medicines: A Review on the Computer-Aided Drug Discovery Approaches over the Past Five Years

por Magwenyane, Ayanda M., Ugbaja, Samuel C., Amoako, Daniel G., Somboro, Anou M., Khan, Rene B., Kumalo, Hezekiel M.
Publicado 2022

Super-Cationic Peptide Dendrimers—Synthesis and Evaluation as Antimicrobial Agents

por Ramchuran, Estelle J., Pérez-Guillén, Isabel, Bester, Linda A., Khan, René, Albericio, Fernando, Viñas, Miguel, de la Torre, Beatriz G.
Publicado 2021

Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design

por Mtambo, Sphamadla E., Amoako, Daniel G., Somboro, Anou M., Agoni, Clement, Lawal, Monsurat M., Gumede, Nelisiwe S., Khan, Rene B., Kumalo, Hezekiel M.
Publicado 2021

New Quinoline–Urea–Benzothiazole Hybrids as Promising Antitubercular Agents: Synthesis, In Vitro Antitubercular Activity, Cytotoxicity Studies, and In Silico ADME Profiling

por Moodley, Rashmika, Mashaba, Chakes, Rakodi, Goitsemodimo H., Ncube, Nomagugu B., Maphoru, Mabuatsela V., Balogun, Mohammed O., Jordan, Audrey, Warner, Digby F., Khan, Rene, Tukulula, Matshawandile
Publicado 2022

Understanding the Hsp90 N-Terminal Dynamics: Structural and Molecular Insights into the Therapeutic Activities of Anticancer Inhibitors Radicicol (RD) and Radicicol Derivative (NVP...

por Magwenyane, Ayanda M., Mhlongo, Ndumiso N., Lawal, Monsurat M., Amoako, Daniel G., Somboro, Anou M., Sosibo, Sphelele C., Shunmugam, Letitia, Khan, Rene B., Kumalo, Hezekiel M.
Publicado 2020

Unveiling the Inhibitory Potentials of Peptidomimetic Azanitriles and Pyridyl Esters towards SARS-CoV-2 Main Protease: A Molecular Modelling Investigation

por Mushebenge, Aganze G., Ugbaja, Samuel C., Mtambo, Sphamandla E., Ntombela, Thandokuhle, Metu, Joy I., Babayemi, Oludotun, Chima, Joy I., Appiah-Kubi, Patrick, Odugbemi, Adeshina I., Ntuli, Mthobisi L., Khan, Rene, Kumalo, Hezekiel M.
Publicado 2023