Squalene Emulsion Manufacturing Process Scale-Up for Enhanced Global Pandemic Response

por Phan, Tony, Devine, Christian, Laursen, Erik D., Simpson, Adrian, Kahn, Aaron, Khandhar, Amit P., Mesite, Steven, Besse, Brad, Mabery, Ken J., Flanagan, Elizabeth I., Fox, Christopher B.
Publicado 2020

Accelerated prime-and-trap vaccine regimen in mice using repRNA-based CSP malaria vaccine

por MacMillen, Zachary, Hatzakis, Kiara, Simpson, Adrian, Shears, Melanie J., Watson, Felicia, Erasmus, Jesse H., Khandhar, Amit P., Wilder, Brandon, Murphy, Sean C., Reed, Steven G., Davie, James W., Avril, Marion
Publicado 2023

Reprogramming the adjuvant properties of aluminum oxyhydroxide with nanoparticle technology

por Orr, Mark T., Khandhar, Amit P., Seydoux, Emilie, Liang, Hong, Gage, Emily, Mikasa, Traci, Beebe, Elyse L., Rintala, Nicholas D., Persson, Karin H., Ahniyaz, Anwar, Carter, Darrick, Reed, Steven G., Fox, Christopher B.
Publicado 2019

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern

por Hawman, David W., Meade-White, Kimberly, Archer, Jacob, Leventhal, Shanna, Wilson, Drew, Shaia, Carl, Randall, Samantha, Khandhar, Amit P., Hsiang, Tien-Ying, Gale, Michael, Berglund, Peter, Fuller, Deborah Heydenburg, Feldmann, Heinz, Erasmus, Jesse H.
Publicado 2021

SARS-CoV2 variant-specific replicating RNA vaccines protect from disease following challenge with heterologous variants of concern

por Hawman, David W, Meade-White, Kimberly, Archer, Jacob, Leventhal, Shanna S, Wilson, Drew, Shaia, Carl, Randall, Samantha, Khandhar, Amit P, Krieger, Kyle, Hsiang, Tien-Ying, Gale, Michael, Berglund, Peter, Fuller, Deborah Heydenburg, Feldmann, Heinz, Erasmus, Jesse H
Publicado 2022

Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection

por Erasmus, Jesse H., Archer, Jacob, Fuerte-Stone, Jasmine, Khandhar, Amit P., Voigt, Emily, Granger, Brian, Bombardi, Robin G., Govero, Jennifer, Tan, Qing, Durnell, Lorellin A., Coler, Rhea N., Diamond, Michael S., Crowe, James E., Reed, Steven G., Thackray, Larissa B., Carnahan, Robert H., Van Hoeven, Neal
Publicado 2020

Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

por Hawman, David W., Meade-White, Kimberly, Clancy, Chad, Archer, Jacob, Hinkley, Troy, Leventhal, Shanna S., Rao, Deepashri, Stamper, Allie, Lewis, Matthew, Rosenke, Rebecca, Krieger, Kyle, Randall, Samantha, Khandhar, Amit P., Hao, Linhue, Hsiang, Tien-Ying, Greninger, Alexander L., Gale, Michael, Berglund, Peter, Fuller, Deborah Heydenburg, Rosenke, Kyle, Feldmann, Heinz, Erasmus, Jesse H.
Publicado 2022

Single-dose replicating RNA vaccine induces neutralizing antibodies against SARS-CoV-2 in nonhuman primates

por Erasmus, Jesse H., Khandhar, Amit P., Walls, Alexandra C., Hemann, Emily A., O’Connor, Megan A., Murapa, Patience, Archer, Jacob, Leventhal, Shanna, Fuller, Jim, Lewis, Thomas, Draves, Kevin E., Randall, Samantha, Guerriero, Kathryn A., Duthie, Malcolm S., Carter, Darrick, Reed, Steven G., Hawman, David W., Feldmann, Heinz, Gale, Michael, Veesler, David, Berglund, Peter, Fuller, Deborah Heydenburg
Publicado 2020

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

por Erasmus, Jesse H., Khandhar, Amit P., O’Connor, Megan A., Walls, Alexandra C., Hemann, Emily A., Murapa, Patience, Archer, Jacob, Leventhal, Shanna, Fuller, James T., Lewis, Thomas B., Draves, Kevin E., Randall, Samantha, Guerriero, Kathryn A., Duthie, Malcolm S., Carter, Darrick, Reed, Steven G., Hawman, David W., Feldmann, Heinz, Gale, Michael, Veesler, David, Berglund, Peter, Heydenburg Fuller, Deborah
Publicado 2020

A replicon RNA vaccine can induce durable protective immunity from SARS-CoV-2 in nonhuman primates after neutralizing antibodies have waned

por O’Connor, Megan A., Hawman, David W., Meade-White, Kimberly, Leventhal, Shanna, Song, Wenjun, Randall, Samantha, Archer, Jacob, Lewis, Thomas B., Brown, Brieann, Fredericks, Megan N., Sprouse, Kaitlin R., Tunggal, Hillary C., Maughan, Mara, Iwayama, Naoto, Ahrens, Chul, Garrison, William, Wangari, Solomon, Guerriero, Kathryn A., Hanley, Patrick, Lovaglio, Jamie, Saturday, Greg, Veesler, David, Edlefsen, Paul T., Khandhar, Amit P., Feldmann, Heinz, Fuller, Deborah Heydenburg, Erasmus, Jesse H.
Publicado 2023