Does the pursuit of scientific excellence serve or hamper translational medical research: an historical perspective from hematological malignancies

por Bunce, Chris M., Khanim, Farhat L., Drayson, Mark T.
Publicado 2022

Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy

por Pearce, Claire, Hayden, Rachel E, Bunce, Christopher M, Khanim, Farhat L
Publicado 2009

Targeting Asparagine and Serine Metabolism in Germinal Centre-Derived B Cells Non-Hodgkin Lymphomas (B-NHL)

por Eraslan, Zuhal, Papatzikas, Grigorios, Cazier, Jean-Baptiste, Khanim, Farhat L., Günther, Ulrich L.
Publicado 2021

Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: Horizon scanning

por Ward, Kelly, Kitchen, Mark O, Mathias, Suresh-Jay, Khanim, Farhat L, Bryan, Richard T.
Publicado 2022

Malonate as a ROS product is associated with pyruvate carboxylase activity in acute myeloid leukaemia cells

por Reed, Michelle A. C., Ludwig, Christian, Bunce, Christopher M., Khanim, Farhat L., Günther, Ulrich L.
Publicado 2016

Metabolomic Profiling of Drug Responses in Acute Myeloid Leukaemia Cell Lines

por Tiziani, Stefano, Lodi, Alessia, Khanim, Farhat L., Viant, Mark R., Bunce, Christopher M., Günther, Ulrich L.
Publicado 2009

Correction: Metabolomic Profiling of Drug Responses in Acute Myeloid Leukaemia Cell Lines

por Tiziani, Stefano, Lodi, Alessia, Khanim, Farhat L., Viant, Mark R., Bunce, Christopher M., Günther, Ulrich L.
Publicado 2009

Hypoxia Triggers Major Metabolic Changes in AML Cells without Altering Indomethacin-Induced TCA Cycle Deregulation

por Lodi, Alessia, Tiziani, Stefano, Khanim, Farhat L., Drayson, Mark T., Günther, Ulrich L., Bunce, Christopher M., Viant, Mark R.
Publicado 2010

Tracer‐Based Metabolic NMR‐Based Flux Analysis in a Leukaemia Cell Line

por Carrigan, John B., Reed, Michelle A. C., Ludwig, Christian, Khanim, Farhat L., Bunce, Christopher M., Günther, Ulrich L.
Publicado 2016

A framework for tracer-based metabolism in mammalian cells by NMR

por Saborano, Raquel, Eraslan, Zuhal, Roberts, Jennie, Khanim, Farhat L., Lalor, Patricia F., Reed, Michelle A. C., Günther, Ulrich L.
Publicado 2019

Proton NMR-Based Metabolite Analyses of Archived Serial Paired Serum and Urine Samples from Myeloma Patients at Different Stages of Disease Activity Identifies Acetylcarnitine as a...

por Lodi, Alessia, Tiziani, Stefano, Khanim, Farhat L., Günther, Ulrich L., Viant, Mark R., Morgan, Gareth J., Bunce, Christopher M., Drayson, Mark T.
Publicado 2013

Combined bezafibrate, medroxyprogesterone acetate and valproic acid treatment inhibits osteosarcoma cell growth without adversely affecting normal mesenchymal stem cells

por Sheard, Jonathan J., Southam, Andrew D., MacKay, Hannah L., Ellington, Max A., Snow, Martyn D., Khanim, Farhat L., Bunce, Christopher M., Johnson, William E.
Publicado 2021

Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing

por Jiang, Yao, Southam, Andrew D., Trova, Sandro, Beke, Flavio, Alhazmi, Bader, Francis, Thomas, Radotra, Anshul, di Maio, Alessandro, Drayson, Mark T., Bunce, Chris M., Khanim, Farhat L.
Publicado 2021

Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques

por Denbigh, Joanna L., Perez-Guaita, David, Vernooij, Robbin R., Tobin, Mark J., Bambery, Keith R., Xu, Yun, Southam, Andrew D., Khanim, Farhat L., Drayson, Mark T., Lockyer, Nicholas P., Goodacre, Royston, Wood, Bayden R.
Publicado 2017

Pathogen and human NDPK-proteins promote AML cell survival via monocyte NLRP3-inflammasome activation

por Trova, Sandro, Lin, Fei, Lomada, Santosh, Fenton, Matthew, Chauhan, Bhavini, Adams, Alexandra, Puri, Avani, Di Maio, Alessandro, Wieland, Thomas, Sewell, Daniel, Dick, Kirstin, Wiseman, Daniel, Wilks, Deepti P., Goodall, Margaret, Drayson, Mark T., Khanim, Farhat L., Bunce, Christopher M.
Publicado 2023

Combined Bezafibrate and Medroxyprogesterone Acetate: Potential Novel Therapy for Acute Myeloid Leukaemia

por Khanim, Farhat L., Hayden, Rachel E., Birtwistle, Jane, Lodi, Alessia, Tiziani, Stefano, Davies, Nicholas J., Ride, Jon P., Viant, Mark R., Gunther, Ulrich L., Mountford, Joanne C., Schrewe, Heinrich, Green, Richard M., Murray, Jim A., Drayson, Mark T., Bunce, Chris M.
Publicado 2009

The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models

por Davies, Scott P., Mycroft-West, Courtney J., Pagani, Isabel, Hill, Harriet J., Chen, Yen-Hsi, Karlsson, Richard, Bagdonaite, Ieva, Guimond, Scott E., Stamataki, Zania, De Lima, Marcelo Andrade, Turnbull, Jeremy E., Yang, Zhang, Vicenzi, Elisa, Skidmore, Mark A., Khanim, Farhat L., Richardson, Alan
Publicado 2021

The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress

por Gleneadie, Hannah J., Baker, Amy H., Batis, Nikolaos, Bryant, Jennifer, Jiang, Yao, Clokie, Samuel J.H., Mehanna, Hisham, Garcia, Paloma, Gendoo, Deena M.A., Roberts, Sally, Burley, Megan, Molinolo, Alfredo A., Gutkind, J. Silvio, Scheven, Ben A., Cooper, Paul R., Parish, Joanna L., Khanim, Farhat L., Wiench, Malgorzata
Publicado 2021