UV damage induces G3BP1-dependent stress granule formation that is not driven by mTOR inhibition-mediated translation arrest

por Ying, Shan, Khaperskyy, Denys A.
Publicado 2020

Fine-tuning a blunt tool: Regulation of viral host shutoff RNases

por Daly, Raecliffe, Khaperskyy, Denys A., Gaglia, Marta Maria
Publicado 2020

Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein

por Khaperskyy, Denys A., Schmaling, Summer, Larkins-Ford, Jonah, McCormick, Craig, Gaglia, Marta M.
Publicado 2016

Stress Granule-Inducing Eukaryotic Translation Initiation Factor 4A Inhibitors Block Influenza A Virus Replication

por Slaine, Patrick D., Kleer, Mariel, Smith, Nathan K., Khaperskyy, Denys A., McCormick, Craig
Publicado 2017

Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest

por Khaperskyy, Denys A., Emara, Mohamed M., Johnston, Benjamin P., Anderson, Paul, Hatchette, Todd F., McCormick, Craig
Publicado 2014

Nsp1 proteins of human coronaviruses HCoV-OC43 and SARS-CoV2 inhibit stress granule formation

por Dolliver, Stacia M., Kleer, Mariel, Bui-Marinos, Maxwell P., Ying, Shan, Corcoran, Jennifer A., Khaperskyy, Denys A.
Publicado 2022

Thiopurines Activate an Antiviral Unfolded Protein Response That Blocks Influenza A Virus Glycoprotein Accumulation

por Slaine, Patrick D., Kleer, Mariel, Duguay, Brett A., Pringle, Eric S., Kadijk, Eileigh, Ying, Shan, Balgi, Aruna, Roberge, Michel, McCormick, Craig, Khaperskyy, Denys A.
Publicado 2021

Adaptive Mutations in Influenza A/California/07/2009 Enhance Polymerase Activity and Infectious Virion Production

por Slaine, Patrick D., MacRae, Cara, Kleer, Mariel, Lamoureux, Emily, McAlpine, Sarah, Warhuus, Michelle, Comeau, André M., McCormick, Craig, Hatchette, Todd, Khaperskyy, Denys A.
Publicado 2018

The Influenza A Virus Endoribonuclease PA-X Usurps Host mRNA Processing Machinery to Limit Host Gene Expression

por Gaucherand, Lea, Porter, Brittany K., Levene, Rachel E., Price, Emma L., Schmaling, Summer K., Rycroft, Chris H., Kevorkian, Yuzo, McCormick, Craig, Khaperskyy, Denys A., Gaglia, Marta M.
Publicado 2019

Thiopurines inhibit coronavirus Spike protein processing and incorporation into progeny virions

por Pringle, Eric S., Duguay, Brett A., Bui-Marinos, Maxwell P., Mulloy, Rory P., Landreth, Shelby L., Desireddy, Krishna Swaroop, Dolliver, Stacia M., Ying, Shan, Caddell, Taylor, Tooley, Trinity H., Slaine, Patrick D., Bearne, Stephen L., Falzarano, Darryl, Corcoran, Jennifer A., Khaperskyy, Denys A., McCormick, Craig
Publicado 2022

Defective Influenza A Virus RNA Products Mediate MAVS-Dependent Upregulation of Human Leukocyte Antigen Class I Proteins

por Rahim, Mir Munir A., Parsons, Brendon D., Price, Emma L., Slaine, Patrick D., Chilvers, Becca L., Seaton, Gregory S., Wight, Andrew, Medina-Luna, Daniel, Dey, Sayanti, Grandy, Shannen L., Anderson, Lauryn E., Zamorano Cuervo, Natalia, Grandvaux, Nathalie, Gaglia, Marta M., Kelvin, Alyson A., Khaperskyy, Denys A., McCormick, Craig, Makrigiannis, Andrew P.
Publicado 2020