Drugging the unfolded protein response in acute leukemias

por Kharabi Masouleh, Behzad, Chevet, Eric, Panse, Jens, Jost, Edgar, O’Dwyer, Michael, Bruemmendorf, Tim H., Samali, Afshin
Publicado 2015

Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia

por Wilhelm, Thomas, Bick, Fabian, Peters, Kerstin, Mohta, Vrinda, Tirosh, Boaz, Patterson, John B., Kharabi-Masouleh, Behzad, Huber, Michael
Publicado 2017

XBP1 promotes NRAS(G12D) pre‐B acute lymphoblastic leukaemia through IL‐7 receptor signalling and provides a therapeutic vulnerability for oncogenic RAS

por Salimi, Azam, Schemionek‐Reinders, Mirle, Huber, Michael, Vieri, Margherita, Patterson, John B., Alten, Julia, Brümmendorf, Tim H., Kharabi Masouleh, Behzad, Appelmann, Iris
Publicado 2023

A three-gene expression-based risk score can refine the European LeukemiaNet AML classification

por Wilop, Stefan, Chou, Wen-Chien, Jost, Edgar, Crysandt, Martina, Panse, Jens, Chuang, Ming-Kai, Brümmendorf, Tim H., Wagner, Wolfgang, Tien, Hwei-Fang, Kharabi Masouleh, Behzad
Publicado 2016

Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia

por Schemionek, Mirle, Kharabi Masouleh, Behzad, Klaile, Yvonne, Krug, Utz, Hebestreit, Katja, Schubert, Claudia, Dugas, Martin, Büchner, Thomas, Wörmann, Bernhard, Hiddemann, Wolfgang, Berdel, Wolfgang E., Brümmendorf, Tim H., Müller-Tidow, Carsten, Koschmieder, Steffen
Publicado 2015