Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response

por Lucas-Hourani, Marianne, Dauzonne, Daniel, Munier-Lehmann, Hélène, Khiar, Samira, Nisole, Sébastien, Dairou, Julien, Helynck, Olivier, Afonso, Philippe V., Tangy, Frédéric, Vidalain, Pierre-Olivier
Publicado 2017

Identification of a small molecule that primes the type I interferon response to cytosolic DNA

por Khiar, Samira, Lucas-Hourani, Marianne, Nisole, Sébastien, Smith, Nikaïa, Helynck, Olivier, Bourgine, Maryline, Ruffié, Claude, Herbeuval, Jean-Philippe, Munier-Lehmann, Hélène, Tangy, Frédéric, Vidalain, Pierre-Olivier
Publicado 2017

Inhibition of Pyrimidine Biosynthesis Pathway Suppresses Viral Growth through Innate Immunity

por Lucas-Hourani, Marianne, Dauzonne, Daniel, Jorda, Pierre, Cousin, Gaëlle, Lupan, Alexandru, Helynck, Olivier, Caignard, Grégory, Janvier, Geneviève, André-Leroux, Gwénaëlle, Khiar, Samira, Escriou, Nicolas, Desprès, Philippe, Jacob, Yves, Munier-Lehmann, Hélène, Tangy, Frédéric, Vidalain, Pierre-Olivier
Publicado 2013

Evaluation of the Antiviral Activity of Sephin1 Treatment and Its Consequences on eIF2α Phosphorylation in Response to Viral Infections

por Fusade-Boyer, Maxime, Dupré, Gabriel, Bessière, Pierre, Khiar, Samira, Quentin-Froignant, Charlotte, Beck, Cécile, Lecollinet, Sylvie, Rameix-Welti, Marie-Anne, Eléouët, Jean-François, Tangy, Frédéric, Lajoie, Barbora, Bertagnoli, Stéphane, Vidalain, Pierre-Olivier, Gallardo, Franck, Volmer, Romain
Publicado 2019