AKT inhibition mitigates terminal differentiation and preserves central memory phenotype of CD8 T cells

por Abu Eid, Rasha, Friedman, Kevin, Mkrtichyan, Mikayel, Khleif, Samir N
Publicado 2014

High-dose treatment with ADXS11-001, a listeria monocytogenes (Lm)-listeriolysin O (LLO) immunotherapy, in women with cervical cancer

por Ghamande, Sharad, Mauro, David, Price, Cheryl, Wheatley, Donna, Janik, John, Khleif, Samir N
Publicado 2015

Functional redundancy of PI3K isoforms in conventional T cells provides a selective Treg-targeting strategy through inhibition of PI3K-delta isoform

por Ahmad, Shamim, Mkrtichyan, Mikayel, Eid, Rasha Abu, Shrimali, Rajeev, Doroodchi, Atbin, Khleif, Samir N
Publicado 2014

Immuno-Oncology biomarkers 2010 and beyond: Perspectives from the iSBTc/SITC biomarker task force

por Butterfield, Lisa H, Disis, Mary L, Khleif, Samir N, Balwit, James M, Marincola, Francesco M
Publicado 2010

Molecular Characterization of Antigen-Peptide Pulsed Dendritic Cells: Immature Dendritic Cells Develop a Distinct Molecular Profile when Pulsed with Antigen Peptide

por Yang, Amy X., Chong, Numju, Jiang, Yufei, Catalano, Jennifer, Puri, Raj K., Khleif, Samir N.
Publicado 2014

Preamble to the 2015 SITC immunotherapy biomarkers taskforce

por Butterfield, Lisa H, Disis, Mary L, Fox, Bernard A, Khleif, Samir N, Marincola, Francesco M
Publicado 2015

Anti-PD-1 antibody significantly increases therapeutic efficacy of Listeria monocytogenes (Lm)-LLO immunotherapy

por Mkrtichyan, Mikayel, Chong, Namju, Abu Eid, Rasha, Wallecha, Anu, Singh, Reshma, Rothman, John, Khleif, Samir N
Publicado 2013

Akt1 and -2 inhibition diminishes terminal differentiation and enhances central memory CD8(+) T-cell proliferation and survival

por Abu Eid, Rasha, Friedman, Kevin M, Mkrtichyan, Mikayel, Walens, Andrea, King, William, Janik, John, Khleif, Samir N
Publicado 2015

SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art

por Butterfield, Lisa H., Disis, Mary L., Fox, Bernard A., Kaufman, David R., Khleif, Samir N., Wang, Ena
Publicado 2018

Focus on the target: the tumor microenvironment, Society for Immunotherapy of Cancer Annual Meeting Workshop, October 24th-25th 2012

por Sunay, Melek Erdinc, Marincola, Francesco, Khleif, Samir N, Silverstein, Samuel C, Fox, Bernard A, Galon, Jerome, Emens, Leisha A
Publicado 2013

The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors

por Rahma, Osama E, Hamilton, J Michael, Wojtowicz, Malgorzata, Dakheel, Omar, Bernstein, Sarah, Liewehr, David J, Steinberg, Seth M, Khleif, Samir N
Publicado 2014

The “Great Debate” at Immunotherapy Bridge 2022, Naples, November 30th–December 1st, 2022

por Ascierto, Paolo A., Brentjens, Renier, Khleif, Samir N., Odunsi, Kunle, Rezvani, Katayoun, Ruella, Marco, Sullivan, Ryan J., Fox, Bernard A., Puzanov, Igor
Publicado 2023

Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation

por Buchwald, Zachary S., Wynne, Jacob, Nasti, Tahseen H., Zhu, Simeng, Mourad, Waleed F., Yan, Weisi, Gupta, Seema, Khleif, Samir N., Khan, Mohammad K.
Publicado 2018

Agonist anti-GITR antibody significantly enhances the therapeutic efficacy of Listeria monocytogenes-based immunotherapy

por Shrimali, Rajeev, Ahmad, Shamim, Berrong, Zuzana, Okoev, Grigori, Matevosyan, Adelaida, Razavi, Ghazaleh Shoja E., Petit, Robert, Gupta, Seema, Mkrtichyan, Mikayel, Khleif, Samir N.
Publicado 2017

Immune combinational therapy targeting OX40 and IDO synergistically enhances efficacy of a cancer vaccine

por Berrong, Zuzana, Ahmad, Shamim, Abu Eid, Rasha, El Andaloussi, Abdeljabar, Sen, Tanusree, Stewart, Ross, Hammond, Scott A, Shrimali, Rajeev, Mkrtichyan, Mikayel, Khleif, Samir N
Publicado 2014

Shifting the Immune-Suppressive to Predominant Immune-Stimulatory Radiation Effects by SBRT-PArtial Tumor Irradiation Targeting HYpoxic Segment (SBRT-PATHY)

por Tubin, Slavisa, Gupta, Seema, Grusch, Michael, Popper, Helmuth H., Brcic, Luka, Ashdown, Martin L., Khleif, Samir N., Peter-Vörösmarty, Barbara, Hyden, Martin, Negrini, Simone, Fossati, Piero, Hug, Eugen
Publicado 2020

Pre-immature dendritic cells (PIDC) pulsed with HPV16 E6 or E7 peptide are capable of eliciting specific immune response in patients with advanced cervical cancer

por Rahma, Osama E, Herrin, Vincent E, Ibrahim, Rami A, Toubaji, Anton, Bernstein, Sarah, Dakheel, Omar, Steinberg, Seth M, Eid, Rasha Abu, Mkrtichyan, Mikayel, Berzofsky, Jay A, Khleif, Samir N
Publicado 2014

IDO Vaccine Ablates Immune-Suppressive Myeloid Populations and Enhances Antitumor Effects Independent of Tumor Cell IDO Status

por Nandre, Rahul, Verma, Vivek, Gaur, Pankaj, Patil, Veerupaxagouda, Yang, Xingdong, Ramlaoui, Zainab, Shobaki, Nour, Andersen, Mads Hald, Pedersen, Ayako Wakatsuki, Zocca, Mai-Britt, Mkrtichyan, Mikayel, Gupta, Seema, Khleif, Samir N.
Publicado 2022

Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule

por Kaufman, Howard L., Butterfield, Lisa H., Coulie, Pierre G., Demaria, Sandra, Ferris, Robert L., Galon, Jérôme, Khleif, Samir N., Mellman, Ira, Ohashi, Pamela S., Overwijk, Willem W., Topalian, Suzanne L., Marincola, Francesco M.
Publicado 2016

A pilot clinical trial testing mutant von Hippel-Lindau peptide as a novel immune therapy in metastatic Renal Cell Carcinoma

por Rahma, Osama E, Ashtar, Ed, Ibrahim, Ramy, Toubaji, Antoun, Gause, Barry, Herrin, Vincent E, Linehan, W Marston, Steinberg, Seth M, Grollman, Frank, Grimes, George, Bernstein, Sarah A, Berzofsky, Jay A, Khleif, Samir N
Publicado 2010