RNF168 cooperates with RNF8 to mediate FOXM1 ubiquitination and degradation in breast cancer epirubicin treatment

por Kongsema, M, Zona, S, Karunarathna, U, Cabrera, E, Man, E P S, Yao, S, Shibakawa, A, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F
Publicado 2016

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer

por Gong, C, Fujino, K, Monteiro, L J, Gomes, A R, Drost, R, Davidson-Smith, H, Takeda, S, Khoo, U S, Jonkers, J, Sproul, D, Lam, E W-F
Publicado 2015

Forkhead box K2 modulates epirubicin and paclitaxel sensitivity through FOXO3a in breast cancer

por de Moraes, G Nestal, Khongkow, P, Gong, C, Yao, S, Gomes, A R, Ji, Z, Kandola, N, Delbue, D, Man, E P S, Khoo, U S, Sharrocks, A D, Lam, E W-F
Publicado 2015

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance

por Khongkow, P, Gomes, A R, Gong, C, Man, E P S, Tsang, J W-H, Zhao, F, Monteiro, L J, Coombes, R C, Medema, R H, Khoo, U S, Lam, E W-F
Publicado 2016

OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance

por Karunarathna, U, Kongsema, M, Zona, S, Gong, C, Cabrera, E, Gomes, A R, Man, E P S, Khongkow, P, Tsang, J W-H, Khoo, U-S, Medema, R H, Freire, R, Lam, E W-F
Publicado 2016

BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer

por Gong, C, Yao, S, Gomes, A R, Man, E P S, Lee, H J, Gong, G, Chang, S, Kim, S-B, Fujino, K, Kim, S-W, Park, S K, Lee, J W, Lee, M H, Khoo, U S, Lam, E W-F
Publicado 2016