Revisiting the Clinical Importance of DPYD*9A (c.85T>C) Variant of Dihydropyrimidine Dehydrogenase (DPYD) Gene in Patients Treated with Fluoropyrimidine-Based Chemotherapy

por Patel, Girijesh Kumar, Taylor, William, Singh, Seema, Khushman, Moh’d, Singh, Ajay P
Publicado 2018

Comprehensive Analysis of Expression, Clinicopathological Association and Potential Prognostic Significance of RABs in Pancreatic Cancer

por Anand, Shashi, Khan, Mohammad Aslam, Khushman, Moh’d, Dasgupta, Santanu, Singh, Seema, Singh, Ajay Pratap
Publicado 2020

Comparative analysis of exosome isolation methods using culture supernatant for optimum yield, purity and downstream applications

por Patel, Girijesh Kumar, Khan, Mohammad Aslam, Zubair, Haseeb, Srivastava, Sanjeev Kumar, Khushman, Moh’d, Singh, Seema, Singh, Ajay Pratap
Publicado 2019

Vitamin B12 deficiency presenting as pseudo-thrombotic microangiopathy: a case report and literature review

por Fahmawi, Yazan, Campos, Yesica, Khushman, Moh’d, Alkharabsheh, Omar, Manne, Ashish, Zubair, Haseeb, Haleema, Saadia, Polski, Jacek, Bessette, Sabrina
Publicado 2019

Exosomal Formulation Escalates Cellular Uptake of Honokiol Leading to the Enhancement of Its Antitumor Efficacy

por Kanchanapally, Rajashekhar, Khan, Mohammad Aslam, Deshmukh, Sachin Kumar, Srivastava, Sanjeev Kumar, Khushman, Moh’d, Singh, Seema, Singh, Ajay Pratap
Publicado 2020

Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward

por Khan, Mohammad Aslam, Azim, Shafquat, Zubair, Haseeb, Bhardwaj, Arun, Patel, Girijesh Kumar, Khushman, Moh’d, Singh, Seema, Singh, Ajay Pratap
Publicado 2017

The prevalence and clinical relevance of 2R/2R TYMS genotype in patients with gastrointestinal malignancies treated with fluoropyrimidine-based chemotherapy regimens

por Khushman, Moh’d, Patel, Girijesh Kumar, Maharjan, Anu Singh, McMillin, Gwendolyn A., Nelson, Cindy, Hosein, Peter, Singh, Ajay P.
Publicado 2021

Deep sequencing and in silico analyses identify MYB-regulated gene networks and signaling pathways in pancreatic cancer

por Azim, Shafquat, Zubair, Haseeb, Srivastava, Sanjeev K., Bhardwaj, Arun, Zubair, Asif, Ahmad, Aamir, Singh, Seema, Khushman, Moh’d., Singh, Ajay P.
Publicado 2016

Detection of mitochondrial DNA mutations in circulating mitochondria-originated extracellular vesicles for potential diagnostic applications in pancreatic adenocarcinoma

por Vikramdeo, Kunwar Somesh, Anand, Shashi, Khan, Mohammad Aslam, Khushman, Moh’d, Heslin, Martin J., Singh, Seema, Singh, Ajay Pratap, Dasgupta, Santanu
Publicado 2022

Clinical and Hematological Predictors of High-Grade Immune-Related Adverse Events Associated With Immune Checkpoint Inhibitors

por Manne, Ashish, Mulekar, Madhuri S., Escobar, Daisy E., Alsayed, Alhareth, Sharma, Gaurav, Prodduturvar, Pranitha, Khushman, Moh’d, Howard, John Harrison, Gilbert, Robert, Alkharabsheh, Omar
Publicado 2021

Exosomes confer chemoresistance to pancreatic cancer cells by promoting ROS detoxification and miR-155-mediated suppression of key gemcitabine-metabolising enzyme, DCK

por Patel, Girijesh Kumar, Khan, Mohammad Aslam, Bhardwaj, Arun, Srivastava, Sanjeev K, Zubair, Haseeb, Patton, Mary C, Singh, Seema, Khushman, Moh'd, Singh, Ajay P
Publicado 2017

The impact of neoadjuvant concurrent chemoradiation on exosomal markers (CD63 and CD9) expression and their prognostic significance in patients with rectal adenocarcinoma

por Khushman, Moh’d, Prodduturvar, Pranitha, Mneimneh, Wadad, Zotto, Valeria Dal, Akbar, Shalla, Grimm, Leander, Rider, Paul, Hunter, John, Alkharabsheh, Omar, Patel, Girijesh Kumar, Fabregas, Jesus C., Singh, Ajay P.
Publicado 2021

DCZ0415, a small‐molecule inhibitor targeting TRIP13, inhibits EMT and metastasis via inactivation of the FGFR4/STAT3 axis and the Wnt/β‐catenin pathway in colorectal cancer

por Agarwal, Sumit, Afaq, Farrukh, Bajpai, Prachi, Kim, Hyung‐Gyoon, Elkholy, Amr, Behring, Michael, Chandrashekar, Darshan Shimoga, Diffalha, Sameer Al, Khushman, Moh’d, Sugandha, Shajan P., Varambally, Sooryanarayana, Manne, Upender
Publicado 2022

Genomic Landscape of Angiosarcoma: A Targeted and Immunotherapy Biomarker Analysis

por Espejo-Freire, Andrea P., Elliott, Andrew, Rosenberg, Andrew, Costa, Philippos Apolinario, Barreto-Coelho, Priscila, Jonczak, Emily, D’Amato, Gina, Subhawong, Ty, Arshad, Junaid, Diaz-Perez, Julio A., Korn, William M., Oberley, Matthew J., Magee, Daniel, Dizon, Don, von Mehren, Margaret, Khushman, Moh’d M., Hussein, Atif Mahmoud, Leu, Kirsten, Trent, Jonathan C.
Publicado 2021

Molecular profile of BRCA-mutated biliary tract cancers

por Spizzo, Gilbert, Puccini, Alberto, Xiu, Joanne, Goldberg, Richard M, Grothey, Axel, Shields, Anthony F, Arora, Sukeshi Patel, Khushman, Moh’d, Salem, Mohamed E, Battaglin, Francesca, Baca, Yasmine, El-Deiry, Wafik S, Philip, Philip A, Nassem, Madiha, Hall, Michael, Marshall, John L, Kocher, Florian, Amann, Arno, Wolf, Dominik, Korn, W Michael, Lenz, Heinz-Josef, Seeber, Andreas
Publicado 2020

Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients

por Puccini, Alberto, Seeber, Andreas, Xiu, Joanne, Goldberg, Richard M., Soldato, Davide, Grothey, Axel, Shields, Anthony F., Salem, Mohamed E., Battaglin, Francesca, Berger, Martin D., El-Deiry, Wafik S., Tokunaga, Ryuma, Naseem, Madiha, Zhang, Wu, Arora, Sukeshi Patel, Khushman, Moh’d M., Hall, Michael J., Philip, Philip A., Marshall, John L., Korn, W. Michael, Lenz, Heinz-Josef
Publicado 2021

PBRM1 mutations might render a subtype of biliary tract cancers sensitive to drugs targeting the DNA damage repair system

por Zimmer, Kai, Kocher, Florian, Untergasser, Gerold, Kircher, Brigitte, Amann, Arno, Baca, Yasmine, Xiu, Joanne, Korn, W. Micheal, Berger, Martin D., Lenz, Heinz-Josef, Puccini, Alberto, Fontana, Elisa, Shields, Anthony F., Marshall, John L., Hall, Michael, El-Deiry, Wafik S., Hsiehchen, David, Macarulla, Teresa, Tabernero, Josep, Pichler, Renate, Khushman, Moh’d, Manne, Upender, Lou, Emil, Wolf, Dominik, Sokolova, Viktorija, Schnaiter, Simon, Zeimet, Alain G., Gulhati, Pat, Widmann, Gerlig, Seeber, Andreas
Publicado 2023