Using Mendelian randomization to understand and develop treatments for neurodegenerative disease

por Storm, Catherine S, Kia, Demis A, Almramhi, Mona, Wood, Nicholas W
Publicado 2020

Genome, transcriptome and proteome: the rise of omics data and their integration in biomedical sciences

por Manzoni, Claudia, Kia, Demis A, Vandrovcova, Jana, Hardy, John, Wood, Nicholas W, Lewis, Patrick A, Ferrari, Raffaele
Publicado 2016

Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome

por Storm, Catherine S., Kia, Demis A., Almramhi, Mona M., Bandres-Ciga, Sara, Finan, Chris, Hingorani, Aroon D., Wood, Nicholas W.
Publicado 2021

Stratification of candidate genes for Parkinson’s disease using weighted protein-protein interaction network analysis

por Ferrari, Raffaele, Kia, Demis A., Tomkins, James E., Hardy, John, Wood, Nicholas W., Lovering, Ruth C., Lewis, Patrick A., Manzoni, Claudia
Publicado 2018

Age‐related telomere attrition in the human putamen

por Schreglmann, Sebastian R., Goncalves, Tomas, Grant‐Peters, Melissa, Kia, Demis A., Soreq, Lilach, Ryten, Mina, Wood, Nicholas W., Bhatia, Kailash P., Tomita, Kazunori
Publicado 2023

Exploring the Role of Plasma Lipids and Statin Interventions on Multiple Sclerosis Risk and Severity: A Mendelian Randomization Study

por Almramhi, Mona M., Finan, Chris, Storm, Catherine S., Schmidt, Amand F., Kia, Demis A., Coneys, Rachel, Chopade, Sandesh, Hingorani, Aroon D., Wood, Nick W.
Publicado 2023

Mendelian Randomization Study Shows No Causal Relationship Between Circulating Urate Levels and Parkinson’s Disease

por Kia, Demis A., Noyce, Alastair J., White, Jon, Speed, Doug, Nicolas, Aude, Burgess, Stephen, Lawlor, Debbie A., Smith, George Davey, Singleton, Andrew, Nalls, Mike A., Sofat, Reecha, Wood, Nicholas W.
Publicado 2018

Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data Sets

por Kia, Demis A., Zhang, David, Guelfi, Sebastian, Manzoni, Claudia, Hubbard, Leon, Reynolds, Regina H., Botía, Juan, Ryten, Mina, Ferrari, Raffaele, Lewis, Patrick A., Williams, Nigel, Trabzuni, Daniah, Hardy, John, Wood, Nicholas W.
Publicado 2021

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study

por Noyce, Alastair J., Kia, Demis A., Hemani, Gibran, Nicolas, Aude, Price, T. Ryan, De Pablo-Fernandez, Eduardo, Haycock, Philip C., Lewis, Patrick A., Foltynie, Thomas, Davey Smith, George, Schrag, Anette, Lees, Andrew J., Hardy, John, Singleton, Andrew, Nalls, Mike A., Pearce, Neil, Lawlor, Debbie A., Wood, Nicholas W.
Publicado 2017

The Parkinson's Disease Mendelian Randomization Research Portal

por Noyce, Alastair J., Bandres‐Ciga, Sara, Kim, Jonggeol, Heilbron, Karl, Kia, Demis, Hemani, Gibran, Xue, Angli, Lawlor, Debbie A., Smith, George Davey, Duran, Raquel, Gan‐Or, Ziv, Blauwendraat, Cornelis, Gibbs, J. Raphael, Hinds, David A., Yang, Jian, Visscher, Peter, Cuzick, Jack, Morris, Huw, Hardy, John, Wood, Nicholas W., Nalls, Mike A., Singleton, Andrew B.
Publicado 2019

Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci

por Soutar, Marc P M, Melandri, Daniela, O’Callaghan, Benjamin, Annuario, Emily, Monaghan, Amy E, Welsh, Natalie J, D’Sa, Karishma, Guelfi, Sebastian, Zhang, David, Pittman, Alan, Trabzuni, Daniah, Verboven, Anouk H A, Pan, Kylie S, Kia, Demis A, Bictash, Magda, Gandhi, Sonia, Houlden, Henry, Cookson, Mark R, Kasri, Nael Nadif, Wood, Nicholas W, Singleton, Andrew B, Hardy, John, Whiting, Paul J, Blauwendraat, Cornelis, Whitworth, Alexander J, Manzoni, Claudia, Ryten, Mina, Lewis, Patrick A, Plun-Favreau, Hélène
Publicado 2022

C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts

por Costa, Beatrice, Manzoni, Claudia, Bernal-Quiros, Manuel, Kia, Demis A., Aguilar, Miquel, Alvarez, Ignacio, Alvarez, Victoria, Andreassen, Ole, Anfossi, Maria, Bagnoli, Silvia, Benussi, Luisa, Bernardi, Livia, Binetti, Giuliano, Blackburn, Daniel, Boada, Mercè, Borroni, Barbara, Bowns, Lucy, Bråthen, Geir, Bruni, Amalia C., Chiang, Huei-Hsin, Clarimon, Jordi, Colville, Shuna, Conidi, Maria E., Cope, Tom E., Cruchaga, Carlos, Cupidi, Chiara, Di Battista, Maria Elena, Diehl-Schmid, Janine, Diez-Fairen, Monica, Dols-Icardo, Oriol, Durante, Elisabetta, Flisar, Dušan, Frangipane, Francesca, Galimberti, Daniela, Gallo, Maura, Gallucci, Maurizio, Ghidoni, Roberta, Graff, Caroline, Grafman, Jordan H., Grossman, Murray, Hardy, John, Hernández, Isabel, Holloway, Guy J.T., Huey, Edward D., Illán-Gala, Ignacio, Karydas, Anna, Khoshnood, Behzad, Kramberger, Milica G., Kristiansen, Mark, Lewis, Patrick A., Lleó, Alberto, Madhan, Gaganjit K., Maletta, Raffaele, Maver, Aleš, Menendez-Gonzalez, Manuel, Milan, Graziella, Miller, Bruce, Mol, Merel O., Momeni, Parastoo, Moreno-Grau, Sonia, Morris, Chris M., Nacmias, Benedetta, Nilsson, Christer, Novelli, Valeria, Öijerstedt, Linn, Padovani, Alessandro, Pal, Suvankar, Panchbhaya, Yasmin, Pastor, Pau, Peterlin, Borut, Piaceri, Irene, Pickering-Brown, Stuart, Pijnenburg, Yolande A.L., Puca, Annibale A., Rainero, Innocenzo, Rendina, Antonella, Richardson, Anna M.T., Rogaeva, Ekaterina, Rogelj, Boris, Rollinson, Sara, Rossi, Giacomina, Rossmeier, Carola, Rowe, James B., Rubino, Elisa, Ruiz, Agustín, Sanchez-Valle, Raquel, Sando, Sigrid B., Santillo, Alexander F., Saxon, Jennifer, Scarpini, Elio, Serpente, Maria, Smirne, Nicoletta, Sorbi, Sandro, Suh, EunRan, Tagliavini, Fabrizio, Thompson, Jennifer C., Trojanowski, John Q., Van Deerlin, Vivianna M., Van der Zee, Julie, Van Broeckhoven, Christine, van Rooij, Jeroen, Van Swieten, John C., Veronesi, Arianna, Vitale, Emilia, Waldö, Maria L., Woodward, Cathy, Yokoyama, Jennifer, Escott-Price, Valentina, Polke, James M., Ferrari, Raffaele
Publicado 2020