Properties and Therapeutic Implications of an Enigmatic D477G RPE65 Variant Associated with Autosomal Dominant Retinitis Pigmentosa

por Kiang, Anna-Sophia, Kenna, Paul F., Humphries, Marian M., Ozaki, Ema, Koenekoop, Robert K., Campbell, Matthew, Farrar, G. Jane, Humphries, Pete
Publicado 2020

Toward an elucidation of the molecular genetics of inherited retinal degenerations

por Farrar, G. Jane, Carrigan, Matthew, Dockery, Adrian, Millington-Ward, Sophia, Palfi, Arpad, Chadderton, Naomi, Humphries, Marian, Kiang, Anna Sophia, Kenna, Paul F., Humphries, Pete
Publicado 2017

Advanced late-onset retinitis pigmentosa with dominant-acting D477G RPE65 mutation is responsive to oral synthetic retinoid therapy

por Kenna, Paul F, Humphries, Marian M, Kiang, Anna-Sophia, Brabet, Philippe, Guillou, Laurent, Ozaki, Ema, Campbell, Matthew, Farrar, G Jane, Koenekoop, Robert, Humphries, Pete
Publicado 2020

Systemic low-molecular weight drug delivery to pre-selected neuronal regions

por Campbell, Matthew, Humphries, Marian M, Kiang, Anna-Sophia, Nguyen, Anh T H, Gobbo, Oliviero L, Tam, Lawrence C S, Suzuki, Mayu, Hanrahan, Finnian, Ozaki, Ema, Farrar, G-Jane, Kenna, Paul F, Humphries, Peter
Publicado 2011

siRNA targeting Schlemm’s canal endothelial tight junctions enhances outflow facility and reduces IOP in a steroid-induced OHT rodent model

por Cassidy, Paul S., Kelly, Ruth A., Reina-Torres, Ester, Sherwood, Joseph M., Humphries, Marian M., Kiang, Anna-Sophia, Farrar, G. Jane, O’Brien, Colm, Campbell, Matthew, Stamer, W. Daniel, Overby, Darryl R., Humphries, Pete, O’Callaghan, Jeffrey
Publicado 2020

Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma

por O’Callaghan, Jeffrey, Crosbie, Darragh. E., Cassidy, Paul. S., Sherwood, Joseph M., Flügel-Koch, Cassandra, Lütjen-Drecoll, Elke, Humphries, Marian M., Reina-Torres, Ester, Wallace, Deborah, Kiang, Anna-Sophia, Campbell, Matthew, Stamer, W. Daniel, Overby, Darryl R., O’Brien, Colm, Tam, Lawrence C. S., Humphries, Peter
Publicado 2017

Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm’s Canal Endothelia

por Tam, Lawrence C. S., Reina-Torres, Ester, Sherwood, Joseph M., Cassidy, Paul S., Crosbie, Darragh E., Lütjen-Drecoll, Elke, Flügel-Koch, Cassandra, Perkumas, Kristin, Humphries, Marian M., Kiang, Anna-Sophia, O’Callaghan, Jeffrey, Callanan, John J., Read, A. Thomas, Ethier, C. Ross, O’Brien, Colm, Lawrence, Matthew, Campbell, Matthew, Stamer, W. Daniel, Overby, Darryl R., Humphries, Pete
Publicado 2017