Biomarkers of autoimmunity and beta cell metabolism in type 1 diabetes

por Yang, Mei-Ling, Kibbey, Richard G., Mamula, Mark J.
Publicado 2022

The LDL Receptor Clustering Motif Interacts with the Clathrin Terminal Domain in a Reverse Turn Conformation

por Kibbey, Richard G., Rizo, Josep, Gierasch, Lila M., Anderson, Richard G.W.
Publicado 1998

UCP2-dependent redox sensing in POMC neurons regulates feeding

por Yoon, Nal Ae, Jin, Sungho, Kim, Jung Dae, Liu, Zhong Wu, Sun, Qiushi, Cardone, Rebecca, Kibbey, Richard, Diano, Sabrina
Publicado 2022

Phosphoenolpyruvate Cycling via Mitochondrial Phosphoenolpyruvate Carboxykinase Links Anaplerosis and Mitochondrial GTP with Insulin Secretion

por Stark, Romana, Pasquel, Francisco, Turcu, Adina, Pongratz, Rebecca L., Roden, Michael, Cline, Gary W., Shulman, Gerald I., Kibbey, Richard G.
Publicado 2009

SGLT2 knockout prevents hyperglycemia and is associated with reduced pancreatic β-cell death in genetically obese mice

por Jurczak, Michael J., Saini, Saumya, Ioja, Simona, Costa, Diana K., Udeh, Nnamdi, Zhao, Xiaojian, Whaley, Jean M., Kibbey, Richard G.
Publicado 2018

Dehydration and insulinopenia are necessary and sufficient for euglycemic ketoacidosis in SGLT2 inhibitor-treated rats

por Perry, Rachel J., Rabin-Court, Aviva, Song, Joongyu D., Cardone, Rebecca L., Wang, Yongliang, Kibbey, Richard G., Shulman, Gerald I.
Publicado 2019

Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells

por Song, Jae-Eun, Alves, Tiago C., Stutz, Bernardo, Šestan-Peša, Matija, Kilian, Nicole, Jin, Sungho, Diano, Sabrina, Kibbey, Richard G., Horvath, Tamas L.
Publicado 2021

Development of a Bioartificial Vascular Pancreas

por Han, Edward X, Wang, Juan, Kural, Mehmet, Jiang, Bo, Leiby, Katherine L, Chowdhury, Nazar, Tellides, George, Kibbey, Richard G, Lawson, Jeffrey H, Niklason, Laura E
Publicado 2021

Glucose Response by Stem Cell-Derived β Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis

por Davis, Jeffrey C., Alves, Tiago C., Helman, Aharon, Chen, Jonathan C., Kenty, Jennifer H., Cardone, Rebecca L., Liu, David R., Kibbey, Richard G., Melton, Douglas A.
Publicado 2020

Propionate Increases Hepatic Pyruvate Cycling and Anaplerosis and Alters Mitochondrial Metabolism

por Perry, Rachel J., Borders, Candace B., Cline, Gary W., Zhang, Xian-Man, Alves, Tiago C., Petersen, Kitt Falk, Rothman, Douglas L., Kibbey, Richard G., Shulman, Gerald I.
Publicado 2016

Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis Throughout the Day

por Malik, Dania M., Rhoades, Seth D., Zhang, Shirley L., Sengupta, Arjun, Barber, Annika, Haynes, Paula, Arnadottir, Erna Sif, Pack, Allan, Kibbey, Richard G., Sehgal, Amita, Weljie, Aalim M.
Publicado 2023

Acetate mediates a microbiome-brain-β cell axis promoting metabolic syndrome

por Perry, Rachel J., Peng, Liang, Barry, Natasha A., Cline, Gary W., Zhang, Dongyan, Cardone, Rebecca L., Petersen, Kitt Falk, Kibbey, Richard G., Goodman, Andrew L., Shulman, Gerald I.
Publicado 2016

Mitochondrial GTP Insensitivity Contributes to Hypoglycemia in Hyperinsulinemia Hyperammonemia by Inhibiting Glucagon Release

por Kibbey, Richard G., Choi, Cheol Soo, Lee, Hui-Young, Cabrera, Over, Pongratz, Rebecca L., Zhao, Xiaojian, Birkenfeld, Andreas L., Li, Changhong, Berggren, Per-Olof, Stanley, Charles, Shulman, Gerald I.
Publicado 2014

NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart

por Zhang, Hong, Xiao, Yang, Nederlof, Rianne, Bakker, Diane, Zhang, Pengbo, Girardin, Stephen E., Hollmann, Markus W., Weber, Nina C., Houten, Sander M., van Weeghel, Michel, Kibbey, Richard G., Zuurbier, Coert J.
Publicado 2020

A Single Virtual Consult Reduces Severe Hyperglycemia in Patients Admitted with COVID19 Infection

por Athonvarangkul, Diana, Gunawan, Felona, Nagel, Kathryn, Bak, Leigh, Herold, Kevan C, Hwang, Janice Jin, Jastreboff, Ania M, Kibbey, Richard, Shulman, Gerald I, Vatner, Daniel, Alausa, Jameel, Subair, Labeebah, Inzucchi, Silvio E
Publicado 2021

Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice

por Bhat, Neha, Narayanan, Anand, Fathzadeh, Mohsen, Kahn, Mario, Zhang, Dongyan, Goedeke, Leigh, Neogi, Arpita, Cardone, Rebecca L., Kibbey, Richard G., Fernandez-Hernando, Carlos, Ginsberg, Henry N., Jain, Dhanpat, Shulman, Gerald I., Mani, Arya
Publicado 2022

SGLT2 Deletion Improves Glucose Homeostasis and Preserves Pancreatic β-Cell Function

por Jurczak, Michael J., Lee, Hui-Young, Birkenfeld, Andreas L., Jornayvaz, Francois R., Frederick, David W., Pongratz, Rebecca L., Zhao, Xiaoxian, Moeckel, Gilbert W., Samuel, Varman T., Whaley, Jean M., Shulman, Gerald I., Kibbey, Richard G.
Publicado 2011

β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the K(ATP) channel

por Foster, Hannah R, Ho, Thuong, Potapenko, Evgeniy, Sdao, Sophia M, Huang, Shih Ming, Lewandowski, Sophie L, VanDeusen, Halena R, Davidson, Shawn M, Cardone, Rebecca L, Prentki, Marc, Kibbey, Richard G, Merrins, Matthew J
Publicado 2022

Citrullination of glucokinase is linked to autoimmune diabetes

por Yang, Mei-Ling, Horstman, Sheryl, Gee, Renelle, Guyer, Perrin, Lam, TuKiet T., Kanyo, Jean, Perdigoto, Ana L., Speake, Cate, Greenbaum, Carla J., Callebaut, Aïsha, Overbergh, Lut, Kibbey, Richard G., Herold, Kevan C., James, Eddie A., Mamula, Mark J.
Publicado 2022

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

por Madiraju, Anila K., Erion, Derek M., Rahimi, Yasmeen, Zhang, Xian-Man, Braddock, Demetrios, Albright, Ronald A., Prigaro, Brett J., Wood, John L., Bhanot, Sanjay, MacDonald, Michael J., Jurczak, Michael, Camporez, Joao-Paulo, Lee, Hui-Young, Cline, Gary W., Samuel, Varman T., Kibbey, Richard G., Shulman, Gerald I.
Publicado 2014