Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin

por Kihn, Kyle, Marchiori, Elisa, Spagnolli, Giovanni, Boldrini, Alberto, Terruzzi, Luca, Lawrence, Daniel A., Gershenson, Anne, Faccioli, Pietro, Wintrode, Patrick L.
Publicado 2022

Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding pa...

por Smith, Caroline N., Kihn, Kyle, Williamson, Zachary A., Chow, K. Martin, Hersh, Louis B., Korotkov, Konstantin V., Deredge, Daniel, Blackburn, Jessica S.
Publicado 2023

The conformational landscape of a serpin N-terminal subdomain facilitates folding and in-cell quality control

por Kaur, Upneet, Kihn, Kyle C., Ke, Haiping, Kuo, Weiwei, Gierasch, Lila M., Hebert, Daniel N., Wintrode, Patrick L., Deredge, Daniel, Gershenson, Anne
Publicado 2023

Structure and dynamics of an α-fucosidase reveal a mechanism for highly efficient IgG transfucosylation

por Klontz, Erik H., Li, Chao, Kihn, Kyle, Fields, James K., Beckett, Dorothy, Snyder, Greg A., Wintrode, Patrick L., Deredge, Daniel, Wang, Lai-Xi, Sundberg, Eric J.
Publicado 2020

Molecular Basis of Selective Cytokine Signaling Inhibition by Antibodies Targeting a Shared Receptor

por Fields, James K., Kihn, Kyle, Birkedal, Gabriel S., Klontz, Erik H., Sjöström, Kjell, Günther, Sebastian, Beadenkopf, Robert, Forsberg, Göran, Liberg, David, Snyder, Greg A., Deredge, Daniel, Sundberg, Eric J.
Publicado 2021