Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster

por Holzer, Sandro, Yan, Jiangyu, Kilkenny, Mairi L., Bell, Stephen D., Pellegrini, Luca
Publicado 2017

A Conserved Motif in the C-terminal Tail of DNA Polymerase α Tethers Primase to the Eukaryotic Replisome

por Kilkenny, Mairi L., De Piccoli, Giacomo, Perera, Rajika L., Labib, Karim, Pellegrini, Luca
Publicado 2012

The human CTF4-orthologue AND-1 interacts with DNA polymerase α/primase via its unique C-terminal HMG box

por Kilkenny, Mairi L., Simon, Aline C., Mainwaring, Jack, Wirthensohn, David, Holzer, Sandro, Pellegrini, Luca
Publicado 2017

Mechanism for priming DNA synthesis by yeast DNA Polymerase α

por Perera, Rajika L, Torella, Rubben, Klinge, Sebastian, Kilkenny, Mairi L, Maman, Joseph D, Pellegrini, Luca
Publicado 2013

Structural Basis for Inhibition of Human Primase by Arabinofuranosyl Nucleoside Analogues Fludarabine and Vidarabine

por Holzer, Sandro, Rzechorzek, Neil J., Short, Isobel R., Jenkyn-Bedford, Michael, Pellegrini, Luca, Kilkenny, Mairi L.
Publicado 2019

Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin

por Holzer, Sandro, Degliesposti, Gianluca, Kilkenny, Mairi L., Maslen, Sarah L., Matak-Vinkovíc, Dijana, Skehel, Mark, Pellegrini, Luca
Publicado 2017

Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin

por Holzer, Sandro, Degliesposti, Gianluca, Kilkenny, Mairi L, Maslen, Sarah L, Matak-Vinkovíc, Dijana, Skehel, Mark, Pellegrini, Luca
Publicado 2020

Structure of an archaeal PCNA1–PCNA2–FEN1 complex: elucidating PCNA subunit and client enzyme specificity

por Doré, Andrew S., Kilkenny, Mairi L., Jones, Sarah A., Oliver, Antony W., Roe, S. Mark, Bell, Stephen D., Pearl, Laurence H.
Publicado 2006

Structural basis for the interaction of SARS‐CoV‐2 virulence factor nsp1 with DNA polymerase α–primase

por Kilkenny, Mairi L., Veale, Charlotte E., Guppy, Amir, Hardwick, Steven W., Chirgadze, Dimitri Y., Rzechorzek, Neil J., Maman, Joseph D., Pellegrini, Luca
Publicado 2021

Ctf4 Is a Hub in the Eukaryotic Replisome that Links Multiple CIP-Box Proteins to the CMG Helicase

por Villa, Fabrizio, Simon, Aline C., Ortiz Bazan, Maria Angeles, Kilkenny, Mairi L., Wirthensohn, David, Wightman, Mel, Matak-Vinkovíc, Dijana, Pellegrini, Luca, Labib, Karim
Publicado 2016

Threonine 57 is required for the post-translational activation of Escherichia coli aspartate α-decarboxylase

por Webb, Michael E., Yorke, Briony A., Kershaw, Tom, Lovelock, Sarah, Lobley, Carina M. C., Kilkenny, Mairi L., Smith, Alison G., Blundell, Tom L., Pearson, Arwen R., Abell, Chris
Publicado 2014

Timeless couples G‐quadruplex detection with processing by DDX11 helicase during DNA replication

por Lerner, Leticia K, Holzer, Sandro, Kilkenny, Mairi L, Šviković, Saša, Murat, Pierre, Schiavone, Davide, Eldridge, Cara B, Bittleston, Alice, Maman, Joseph D, Branzei, Dana, Stott, Katherine, Pellegrini, Luca, Sale, Julian E
Publicado 2020

A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome

por Simon, Aline C., Zhou, Jin C., Perera, Rajika L., van Deursen, Frederick, Evrin, Cecile, Ivanova, Marina E., Kilkenny, Mairi L., Renault, Ludovic, Kjaer, Svend, Matak-Vinković, Dijana, Labib, Karim, Costa, Alessandro, Pellegrini, Luca
Publicado 2014

Involvement of a eukaryotic-like ubiquitin-related modifier in the proteasome pathway of the archaeon Sulfolobus acidocaldarius

por Anjum, Rana S., Bray, Sian M., Blackwood, John K., Kilkenny, Mairi L., Coelho, Matthew A., Foster, Benjamin M., Li, Shurong, Howard, Julie A., Pellegrini, Luca, Albers, Sonja-Verena, Deery, Michael J., Robinson, Nicholas P.
Publicado 2015