Disruption of diphthamide synthesis genes and resulting toxin resistance as a robust technology for quantifying and optimizing CRISPR/Cas9-mediated gene editing

por Killian, Tobias, Dickopf, Steffen, Haas, Alexander K., Kirstenpfad, Claudia, Mayer, Klaus, Brinkmann, Ulrich
Publicado 2017

Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids

por Killian, Tobias, Buntz, Annette, Herlet, Teresa, Seul, Heike, Mundigl, Olaf, Längst, Gernot, Brinkmann, Ulrich
Publicado 2019

TriFabs—Trivalent IgG-Shaped Bispecific Antibody Derivatives: Design, Generation, Characterization and Application for Targeted Payload Delivery

por Mayer, Klaus, Baumann, Anna-Lena, Grote, Michael, Seeber, Stefan, Kettenberger, Hubert, Breuer, Sebastian, Killian, Tobias, Schäfer, Wolfgang, Brinkmann, Ulrich
Publicado 2015

Quantitative fluorescence imaging determines the absolute number of locked nucleic acid oligonucleotides needed for suppression of target gene expression

por Buntz, Annette, Killian, Tobias, Schmid, Daniela, Seul, Heike, Brinkmann, Ulrich, Ravn, Jacob, Lindholm, Marie, Knoetgen, Hendrik, Haucke, Volker, Mundigl, Olaf
Publicado 2019

A Novel Antibody against Human Properdin Inhibits the Alternative Complement System and Specifically Detects Properdin from Blood Samples

por Pauly, Diana, Nagel, Benedikt M., Reinders, Jörg, Killian, Tobias, Wulf, Matthias, Ackermann, Susanne, Ehrenstein, Boris, Zipfel, Peter F., Skerka, Christine, Weber, Bernhard H. F.
Publicado 2014