Repurposing the anti-epileptic drug sodium valproate as an adjuvant treatment for diffuse intrinsic pontine glioma

por Killick-Cole, Clare L., Singleton, William G. B., Bienemann, Alison S., Asby, Daniel J., Wyatt, Marcella J., Boulter, Lisa J., Barua, Neil U., Gill, Steven S.
Publicado 2017

Combined use of CDK4/6 and mTOR inhibitors induce synergistic growth arrest of diffuse intrinsic pontine glioma cells via mutual downregulation of mTORC1 activity

por Asby, Daniel J, Killick-Cole, Clare L, Boulter, Lisa J, Singleton, William GB, Asby, Claire A, Wyatt, Marcella J, Barua, Neil U, Bienemann, Alison S, Gill, Steven S
Publicado 2018

Childhood Brain Tumors: A Review of Strategies to Translate CNS Drug Delivery to Clinical Trials

por Rahman, Ruman, Janowski, Miroslaw, Killick-Cole, Clare L., Singleton, William G. B., Campbell, Emma, Walczak, Piotr, Khatua, Soumen, Faltings, Lukas, Symons, Marc, Schneider, Julia R., Kwan, Kevin, Boockvar, John A., Gill, Steven S., Oliveira, J. Miguel, Beccaria, Kevin, Carpentier, Alexandre, Canney, Michael, Pearl, Monica, Veal, Gareth J., Meijer, Lisethe, Walker, David A.
Publicado 2023

shRNA‐mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth

por Haynes, Harry R, Scott, Helen L, Killick‐Cole, Clare L, Shaw, Gary, Brend, Tim, Hares, Kelly M, Redondo, Juliana, Kemp, Kevin C, Ballesteros, Lorena S, Herman, Andrew, Cordero‐Llana, Oscar, Singleton, William G, Mills, Francesca, Batstone, Tom, Bulstrode, Harry, Kauppinen, Risto A, Wurdak, Heiko, Uney, James B, Short, Susan C, Wilkins, Alastair, Kurian, Kathreena M
Publicado 2018