Two-pore channels and disease()

por Patel, Sandip, Kilpatrick, Bethan S.
Publicado 2018

Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca(2+) release and Ca(2+) influx

por Kilpatrick, Bethan S., Yates, Elizabeth, Grimm, Christian, Schapira, Anthony H., Patel, Sandip
Publicado 2016

A “mix-and-match” approach to designing Ca(2+) microdomains at membrane-contact sites

por Penny, Christopher J, Kilpatrick, Bethan S, Min Han, Jung, Sneyd, James, Patel, Sandip
Publicado 2014

An Endosomal NAADP-Sensitive Two-Pore Ca(2+) Channel Regulates ER-Endosome Membrane Contact Sites to Control Growth Factor Signaling

por Kilpatrick, Bethan S., Eden, Emily R., Hockey, Leanne N., Yates, Elizabeth, Futter, Clare E., Patel, Sandip
Publicado 2017

The lysosomotrope GPN mobilises Ca(2+) from acidic organelles

por Yuan, Yu, Kilpatrick, Bethan S., Gerndt, Susanne, Bracher, Franz, Grimm, Christian, Schapira, Anthony H., Patel, Sandip
Publicado 2021

Mining of Ebola virus entry inhibitors identifies approved drugs as two-pore channel pore blockers()

por Penny, Christopher J., Vassileva, Kristin, Jha, Archana, Yuan, Yu, Chee, Xavier, Yates, Elizabeth, Mazzon, Michela, Kilpatrick, Bethan S., Muallem, Shmuel, Marsh, Mark, Rahman, Taufiq, Patel, Sandip
Publicado 2019

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition

por Hockey, Leanne N., Kilpatrick, Bethan S., Eden, Emily R., Lin-Moshier, Yaping, Brailoiu, G. Cristina, Brailoiu, Eugen, Futter, Clare E., Schapira, Anthony H., Marchant, Jonathan S., Patel, Sandip
Publicado 2015

Endoplasmic reticulum and lysosomal Ca(2+) stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts

por Kilpatrick, Bethan S., Magalhaes, Joana, Beavan, Michelle S., McNeill, Alisdair, Gegg, Matthew E., Cleeter, Michael W.J., Bloor-Young, Duncan, Churchill, Grant C., Duchen, Michael R., Schapira, Anthony H., Patel, Sandip
Publicado 2016